DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18003 and CARNS1

DIOPT Version :9

Sequence 1:	NP_001027401.1	Gene:	CG18003 / 3771779	FlyBaseID:	FBgn0061356	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	XP_016873543.1	Gene:	CARNS1 / 57571	HGNCID:	29268	Length:	966	Species:	Homo sapiens

Alignment Length:	285	Identity:	59/285 - (20%)
Similarity:	92/285 - (32%)	Gaps:	89/285 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SGAGEQFTLGLNR-EAFRRLRLRPRCLRDVSRLDISTKIFG----EQMQWPLGIAPTAMQKMAHP 86
            ||...|.||.... |||    ||...|.|:  |.::.|:.|    .:..|.|           ||
Human   273 SGKEGQETLVKEEVEAF----LRSEALGDI--LQVAVKLSGWRWRGRQAWRL-----------HP 320

  Fly    87 DGEVGNA--------RAAGKAGSIFILSTLSTTSL--EDLAAGAPDTIKWFQLYIYK---DRTIT 138
            ..|:|..        ....:..|:.:.:......|  .|..:..|.........:.:   ||.:.
Human   321 RAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDGPSPGPGLAVRICAVVCRTQGDRPLL 385

  Fly   139 EKLVRRAEKANFKALVLTIDAPIFGHRRAD--VRNNFSLPSHLSLANFQGVKATGVGNAAMGASG 201
            .|:|                   .|..|.|  :|::.|||..|.:|..|    .|:|..|..|:
Human   386 SKVV-------------------CGVGRGDRPLRHHNSLPRTLEVALAQ----CGLGEEAQVAA- 426

  Fly   202 INEYVSSQFDPTITWKDIAWLKGITHLPIVVKGVLTAEDAVLAQEFGCAGLIVSNHGARQIDTVP 266
            :.:.|.:..:..:.                         ||||.|   |||.....|.|:..|..
Human   427 VRQRVKAAAEAALA-------------------------AVLALE---AGLSAEQRGGRRAHTDF 463

  Fly   267 ASIEALPEIVKAVGDNLVVMLDGGI 291
            ..::........|...:.:.|:||:
Human   464 LGVDFALTAAGGVLTPVALELNGGL 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18003	NP_001027401.1	alpha_hydroxyacid_oxid_FMN	7..353	CDD:239203	59/285 (21%)
CG18003	NP_001027401.1	FMN_dh	17..359	CDD:279418	59/285 (21%)
CARNS1	XP_016873543.1	ATP-grasp_4	663..838	CDD:290269
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140697
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930