Protein Alignment Hao and HAO2

DIOPT Version :10

• Sequence 1: NP_001027401.1
• Gene: Hao / 3771779
• FlyBaseID: FBgn0061356
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: XP_024303252.1
• Gene: HAO2 / 51179
• HGNCID: 4810
• Length: 420
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 159/353 - (45%)
• Similarity: 219/353 - (62%)
• Gaps: 18/353 - (5%)

  Fly     1 MALVCVEDFEKKAVGQLEKNALDYYRSGAGEQFTLGLNREAFRRLRLRPRCLRDVSRLDISTKIF 65
            |:|||:.||:..|..||.|:..|:...||.:..|...|..||:|:|||||.|||||.:|..|.|.
Human    14 MSLVCLTDFQAHAREQLSKSTRDFIEGGADDSITRDDNIAAFKRIRLRPRYLRDVSEVDTRTTIQ 78

  Fly    66 GEQMQWPLGIAPTAMQKMAHPDGEVGNARAAGKAGSIFILSTLSTTSLEDLAAGAPDTIKWFQLY 130
            ||::..|:.||||....:..||||:..||||..||..:|.||.::.||||:...||:.::|||||
Human    79 GEEISAPICIAPTGFHCLVWPDGEMSTARAAQAAGICYITSTFASCSLEDIVIAAPEGLRWFQLY 143

  Fly   131 IYKDRTITEKLVRRAEKANFKALVLTIDAPIFGHRRADVRNNFSLPSHLSLANFQGVKATGVGNA 195
            ::.|..:.::|::|.|...|||||:|:|.|:.|:||.|:||  .|..:|:|.:.|..|.   |||
Human   144 VHPDLQLNKQLIQRVESLGFKALVITLDTPVCGNRRHDIRN--QLRRNLTLTDLQSPKK---GNA 203

  Fly   196 AMGASGINEYVSSQFDPTITWKDIAWLKGITHLPIVVKGVLTAEDAVLAQEFGCAGLIVSNHGAR 260
                  |..:..:....::.|.|::|.:.||.|||::||:||.|||.||.:....|:||||||.|
Human   204 ------IPYFQMTPISTSLCWNDLSWFQSITRLPIILKGILTKEDAELAVKHNVQGIIVSNHGGR 262

  Fly   261 QIDTVPASIEALPEIVKAVGDNLVVMLDGGIMQGNDIFKALALGAKTVFVGRPAVWGLAYNGQKG 325
            |:|.|.|||:||.|:|.||...:.|.||||:..|||:.||||||||.:|:|||.:||||.   |.
Human   263 QLDEVLASIDALTEVVAAVKGKIEVYLDGGVRTGNDVLKALALGAKCIFLGRPILWGLAC---KA 324

  Fly   326 VEEMLSVLRKDFETTMALIGCQNLGDIT 353
            ....|    :..||..:..||:..|.||
Human   325 AGRSL----RSIETWSSFPGCKKKGPIT 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hao	NP_001027401.1	FMN_dh	16..359	CDD:426029	152/338 (45%)
HAO2	XP_024303252.1	FMN_dh	26..326	CDD:426029	145/313 (46%)