Protein Alignment CG10097 and Far1

DIOPT Version :10

• Sequence 1: NP_731699.2
• Gene: CG10097 / 3771756
• FlyBaseID: FBgn0038033
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_081655.2
• Gene: Far1 / 67420
• MGIID: 1914670
• Length: 515
• Species: Mus musculus
• Alignment Length: 499
• Identity: 166/499 - (33%)
• Similarity: 253/499 - (50%)
• Gaps: 35/499 - (7%)

  Fly     5 IISFYKDKTVFITGGTGLLGKVVVEKLLRATD-VKRIYFLVRTKRGEKMEARFESWKKDQVFEVL 68
            |..:|:.|.:.:||.||.||||::|||||:.. |..:|.|||.|.|:..:.|.|.....::|:.|
Mouse     4 IPEYYEGKNILLTGATGFLGKVLLEKLLRSCPRVNSVYVLVRQKAGQTPQERVEEILSSKLFDRL 68

  Fly    69 LNKNPLALEKMTPISGDCCAPDLGISETDRRILAAEVQVLIHGAASVRFEEPLEHAVVINTRAVR 133
            .::||...||:..|:.:...|.|.:||.|:.|:.....|:.|.||:|||.|.|..||.:|..|.|
Mouse    69 RDENPDFREKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATR 133

  Fly   134 LITQLAKEMRLLESFVHVSTAFSNCVVDQIQERFYPEHLSCPVD--KVLDMHNSVSSETFEKMAP 196
            .:..||::|:.||.|:|||||::.|....|.|..||.    |||  |::|....:.......:.|
Mouse   134 QLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPP----PVDPKKLIDSLEWMDDGLVNDITP 194

  Fly   197 ALIGKFPNTYTYTKALGEQVIQEEAKGLPVGIFRPAIILSTFKEPVQGWVDGLQGLIAMIFATAY 261
            .|||..||||.|||||.|.|:|:|...|.|.|.||:|:.:::|||..||:|...|...:..|...
Mouse   195 KLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGK 259

  Fly   262 GFVHLLLVNLKVNAPIVPVDYCVNVAIASAVQIAKISKQNKNGPPPIYAFTPSESN-----LVTY 321
            |.:..:..:....|.:||||..||.::|:    |..|..|:.....:|..|...:|     .|.|
Mouse   260 GILRTMRASNNALADLVPVDVVVNTSLAA----AWYSGVNRPRNIMVYNCTTGSTNPFHWGEVEY 320

  Fly   322 EDLAGLCYQNGLEV----PNAKMIWYPFTHCTRCPYLYNIGILFYHMLPGYLLDIVLRLKGQKPM 382
            ..::.. .:|.||.    ||..:        |....||:..|...|..|.:|.||.||:.|:.|.
Mouse   321 HVISTF-KRNPLEQAFRRPNVNL--------TSNHLLYHYWIAVSHKAPAFLYDIYLRMTGRSPR 376

  Fly   383 MIKSYHKVHEGMRSLLPFSRKTFTMDMKNTNEMWQSMSPEEKEMFNFDMSTLNWKEYFTCLMDGI 447
            |:|:..::|:.|..|..|:..::..:..|.|.:...::||:|:.||.|:..|:|.||......|.
Mouse   377 MMKTITRLHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGT 441

  Fly   448 RLYLFKDLRTPDSVAEGKRILKRFYVLDRILKTVLVTLFGGFIW 491
            :.|:..:  ....:...::.|.:...:.....|:||.|    ||
Mouse   442 KKYVLNE--EMSGLPAARKHLNKLRNIRYGFNTILVIL----IW 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10097	NP_731699.2	FAR-N_SDR_e	12..330	CDD:187547	119/325 (37%)
		Sterile	362..453	CDD:460779	29/90 (32%)
Far1	NP_081655.2	FAR-N_SDR_e	11..330	CDD:187547	119/327 (36%)
		Sterile	357..447	CDD:460779	29/89 (33%)
		Necessary and sufficient for PEX19-mediated localization into peroxisome membrane. /evidence=ECO:0000250|UniProtKB:Q8WVX9	451..507		7/33 (21%)