DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10097 and Far2

DIOPT Version :9

Sequence 1:	NP_001027182.1	Gene:	CG10097 / 3771756	FlyBaseID:	FBgn0038033	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	XP_006237759.1	Gene:	Far2 / 500368	RGDID:	1565966	Length:	515	Species:	Rattus norvegicus

Alignment Length:	515	Identity:	182/515 - (35%)
Similarity:	264/515 - (51%)	Gaps:	57/515 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SEIISFYKDKTVFITGGTGLLGKVVVEKLLRAT-DVKRIYFLVRTKRGEKMEARFESWKKDQVFE 66
            |.|.:||.:|::.|||.||.||||::|||.|.: .:|.||.|||.|.|:.::.|.......::||
  Rat     2 SMIAAFYSNKSILITGATGFLGKVLMEKLFRTSPHLKVIYILVRPKSGQTLQERVFQILNSKLFE 66

  Fly    67 VLLNKNPLALEKMTPISGDCCAPDLGISETDRRILAAEVQVLIHGAASVRFEEPLEHAVVINTRA 131
            .:....|...||:.|||.|....|..||:.|.:.|.:...::.|.||:|||:..|..||.:|..|
  Rat    67 RVKEVCPNVHEKIRPISADLNQRDFAISKEDMQELLSCTNIVFHCAATVRFDAHLREAVQLNVTA 131

  Fly   132 VRLITQLAKEMRLLESFVHVSTAFSNCVVDQIQERFYPEHLSCPVD--KVLDMHNSVSSETFEKM 194
            .:.:..:|.||..||:|:|:|||||||.:..|.|..||    |||:  |::|....:.....|::
  Rat   132 TQQLLLMASEMPKLEAFIHISTAFSNCNLSHIDEVIYP----CPVEPRKIIDSMEWLDDSIIEEI 192

  Fly   195 APALIGKFPNTYTYTKALGEQVIQEEAKGLPVGIFRPAIILSTFKEPVQGWVDGLQGLIAMIFAT 259
            .|.|||..||||||||||||.|:|:|:..|.|.|.||:|:.:|::||..||||.|.|...:|.||
  Rat   193 TPKLIGDRPNTYTYTKALGEVVVQQESGNLNVAIVRPSIVGATWQEPFPGWVDNLNGPSGLIIAT 257

  Fly   260 AYGFVHLLLVNLKVNAPIVPVDYCVNVAIA----SAVQIAKISKQNKNGPPPIYAFTPSESNLVT 320
            ..||:..:.......|.::|||..||:.||    :||...|.:.        ||..|....|...
  Rat   258 GKGFLRSIKATPMAVADLIPVDTVVNLTIAVGWYTAVHRPKSTL--------IYHSTSGNLNPCN 314

  Fly   321 YEDLAGLCYQNGLEV---------------PNAKMIWYPFTHCTRCPYLYNIGILFYHMLPGYLL 370
            :       |:.||:|               |||......||    ..|...:.    |..|..:.
  Rat   315 W-------YEMGLQVLATVEKIPFESAFRRPNADFTTNNFT----TQYWNTVS----HWAPAIIY 364

  Fly   371 DIVLRLKGQKPMMIKSYHKVHEGMRSLLPFSRKTFTMDMKNTNEMWQSMSPEEKEMFNFDMSTLN 435
            |..|||.|:||.|:|..:::.:.:..|..|...::.....||..:...:|||::.:||||:..||
  Rat   365 DFYLRLTGRKPRMLKLMNRLLKTISMLEYFINHSWEWSTNNTEMLLSELSPEDQRVFNFDVRQLN 429

  Fly   436 WKEYFTCLMDGIRLYLFK-DLRTPDSVAEGKRILKRFYVLDRILKTVLVTLFGGFIWLLI 494
            |.||....:.|::.||.| ||.   .:.:.|:.|||...:..:..|.|..:    ||.|:
  Rat   430 WLEYIENYVLGVKKYLLKEDLA---GIPKAKQHLKRLRNIHYLFNTALFLI----IWRLL 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10097	NP_001027182.1	PLN02996	1..453	CDD:215538	170/471 (36%)
		FAR-N_SDR_e	12..330	CDD:187547	126/324 (39%)
		Sterile	363..453	CDD:281068	30/89 (34%)
Far2	XP_006237759.1	FAR-N_SDR_e	11..318	CDD:187547	127/325 (39%)
Far2	XP_006237759.1	Sterile	357..447	CDD:397244	30/89 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351515
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.840