DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10097 and CG1441

DIOPT Version :9

Sequence 1:	NP_001027182.1	Gene:	CG10097 / 3771756	FlyBaseID:	FBgn0038033	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_610535.1	Gene:	CG1441 / 36029	FlyBaseID:	FBgn0033464	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	502	Identity:	146/502 - (29%)
Similarity:	267/502 - (53%)	Gaps:	32/502 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IISFYKDKTVFITGGTGLLGKVVVEKLLRAT-DVKRIYFLVRTKRG----EKMEARFESWKKDQV 64
            |...:|.:::|||||||.||||:||||||:. .:||||.|:|.|:|    |:::..|::...|||
  Fly    28 IAECFKGRSLFITGGTGFLGKVLVEKLLRSCGGLKRIYLLIRPKKGKDPQERIKDIFQNVLFDQV 92

  Fly    65 FEVLLNKNPLALEKMTPISGDCCAPDLGISETDRRILAAEVQVLIHGAASVRFEEPLEHAVVINT 129
            .::...::  .|:::..|:||..:|.|||||.|...|..||.::.|.||:|||:|||.:||.:||
  Fly    93 KQMRGEEH--ILQQVVAIAGDVLSPGLGISEKDLETLRQEVSIVYHCAATVRFDEPLRNAVFMNT 155

  Fly   130 RAVRLITQLAKEMRLLESFVHVSTAFSNCVVDQIQERFYPEHLSCPVD--KVLDMHNSVSSETFE 192
            |..:.:.:||..::.|:.|.:.|||:.:..|..:.|:.|..    |.|  ||:.....::.:...
  Fly   156 RGTKYMLELALTLKHLDFFAYCSTAYCHLHVKTLYEKPYDP----PADPHKVMQACEWLTDDEVA 216

  Fly   193 KMAPALIGKFPNTYTYTKALGEQVIQEEAKGLPVGIFRPAIILSTFKEPVQGWVDGLQGLIAMIF 257
            .:...::|..||||.|||:|.|.::.|:.:.||..|.||:|::..:|||:.||.|.:.|...::.
  Fly   217 TIERKVLGAIPNTYAYTKSLAEALVVEKFEELPAVILRPSIVIPIWKEPIPGWTDNINGPTGLLI 281

  Fly   258 ATAYGFVHLLLVNLKVNAPIVPVDYCVN-VAIASAVQI-AKISKQNKNGPPPIYAFTPSESNLVT 320
            ....|.:..:..|.......:|||..|| :.:||...| |...|.|:     :...|.|....|:
  Fly   282 GAGKGVIRTMYCNSSGYGDFLPVDVAVNGILVASWRNITAGTDKTNR-----VAHMTSSNDIKVS 341

  Fly   321 YEDLAGL---CYQNGLEVPNAKMIWYPFTHCTRCPYLYNIGILFYHMLPGYLLDIVLRLKGQKPM 382
            :.::..|   ..:|  :||...:.|||........:::.|.::.:..:|...:|.:|.:....|:
  Fly   342 WAEIIELGRWVIEN--KVPLNGVAWYPGGSMKSNYWVHFICMVLFQWMPALFVDALLWILRYPPV 404

  Fly   383 MIKSYHKVHEGMRSLLPFSRKTFTMDMKNTNEMWQSMSPEEKEMFNFDMSTLNWKEYFT-CLMDG 446
            :.:..:::::|......::...:..|.....::.:.|:.:|:..:..:...|:..:||| |::..
  Fly   405 LCRVQNRIYKGFEVFEYYANNVWNFDNSEAVKLRKLMNNKERRTYVIEKIELDLIDYFTNCVLCA 469

  Fly   447 IRLYLFKDLRTPDSVAEGKRILKRFYVLDRILKTVLVTLFGGFIWLL 493
            .||.|   ..:.:|:...:|.:|..:|:|::.|.:.:.   |.:::|
  Fly   470 RRLIL---KESDESIPAARRHMKVMWVVDKVYKGIWIF---GILYML 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10097	NP_001027182.1	PLN02996	1..453	CDD:215538	138/460 (30%)
		FAR-N_SDR_e	12..330	CDD:187547	113/329 (34%)
		Sterile	363..453	CDD:281068	16/90 (18%)
CG1441	NP_610535.1	PLN02996	24..464	CDD:215538	133/448 (30%)
		FAR-N_SDR_e	35..348	CDD:187547	112/323 (35%)
		Sterile	385..475	CDD:281068	16/92 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466782
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	8.890