DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10097 and Far2

DIOPT Version :9

Sequence 1:	NP_001027182.1	Gene:	CG10097 / 3771756	FlyBaseID:	FBgn0038033	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001334445.1	Gene:	Far2 / 330450	MGIID:	2687035	Length:	515	Species:	Mus musculus

Alignment Length:	511	Identity:	179/511 - (35%)
Similarity:	266/511 - (52%)	Gaps:	49/511 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SEIISFYKDKTVFITGGTGLLGKVVVEKLLRAT-DVKRIYFLVRTKRGEKMEARFESWKKDQVFE 66
            |.|.:||.:|::.|||.||.||||::|||.|.: .:|.||.|||.|.|:.::.|.......::||
Mouse     2 SMIAAFYSNKSILITGATGFLGKVLMEKLFRTSPHLKVIYILVRPKSGQTLQERVFQILNSKLFE 66

  Fly    67 VLLNKNPLALEKMTPISGDCCAPDLGISETDRRILAAEVQVLIHGAASVRFEEPLEHAVVINTRA 131
            .:....|...||:.|||.|....|..||:.|.:.|.:...::.|.||:|||:..|..||.:|..|
Mouse    67 KVKEVCPNVHEKIRPISADLNQRDFAISKEDVQELLSCTNIIFHCAATVRFDAHLREAVQLNVTA 131

  Fly   132 VRLITQLAKEMRLLESFVHVSTAFSNCVVDQIQERFYPEHLSCPVD--KVLDMHNSVSSETFEKM 194
            .:.:..:|.:|..||:|:|:|||||||.:..|.|..||    |||:  |::|....:.....|::
Mouse   132 TQQLLLMASQMPKLEAFIHISTAFSNCNLSHIDEVIYP----CPVEPRKIIDSMEWLDDSIIEEI 192

  Fly   195 APALIGKFPNTYTYTKALGEQVIQEEAKGLPVGIFRPAIILSTFKEPVQGWVDGLQGLIAMIFAT 259
            .|.|||..||||||||||||.|:|:|:..|.|.|.||:|:.:|::||..||||.|.|...:|.||
Mouse   193 TPKLIGDRPNTYTYTKALGEIVVQQESGNLNVAIVRPSIVGATWQEPFPGWVDNLNGPSGLIIAT 257

  Fly   260 AYGFVHLLLVNLKVNAPIVPVDYCVNVAIA----SAVQIAKISKQNKNGPPPIYAFTPSESN--- 317
            ..||:..:.......|.::|||..||:.||    :||...|.:.        ||..|....|
Mouse   258 GKGFLRSIKATPMAVADVIPVDTVVNLTIAVGWYTAVHRPKSTL--------IYHSTSGNLNPCN 314

  Fly   318 --------LVTYEDLAGLCYQNGLEVPNAKMIWYPFTHCTRCPYLYNIGILFYHMLPGYLLDIVL 374
                    |.|.|.:.   :::....|||     .||......:.:|   ...|.:|..:.|..|
Mouse   315 WYKMGLQVLATIEKIP---FESAFRRPNA-----DFTTSNFTTHYWN---TVSHRVPAIIYDFYL 368

  Fly   375 RLKGQKPMMIKSYHKVHEGMRSLLPFSRKTFTMDMKNTNEMWQSMSPEEKEMFNFDMSTLNWKEY 439
            ||.|:||.|:|..:::.:.:..|..|...::.....||..:...:|||::.:||||:..|||.||
Mouse   369 RLTGRKPRMLKLMNRLLKTISMLEYFINHSWEWSTNNTEMLLSELSPEDQRVFNFDVRQLNWLEY 433

  Fly   440 FTCLMDGIRLYLFK-DLRTPDSVAEGKRILKRFYVLDRILKTVLVTLFGGFIWLLI 494
            ....:.|::.||.| ||.   .:.:.|:.|:|...:..:..|.|..:    ||.|:
Mouse   434 IENYVLGVKKYLLKEDLA---GIPKAKQHLRRLRNIHYLFNTALFLI----IWRLL 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10097	NP_001027182.1	PLN02996	1..453	CDD:215538	168/467 (36%)
		FAR-N_SDR_e	12..330	CDD:187547	128/335 (38%)
		Sterile	363..453	CDD:281068	30/89 (34%)
Far2	NP_001334445.1	FAR-N_SDR_e	11..315	CDD:187547	125/315 (40%)
Far2	NP_001334445.1	Sterile	357..447	CDD:397244	30/89 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847938
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840