DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10097 and fard-1

DIOPT Version :9

Sequence 1:	NP_001027182.1	Gene:	CG10097 / 3771756	FlyBaseID:	FBgn0038033	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001370741.1	Gene:	fard-1 / 180582	WormBaseID:	WBGene00022200	Length:	536	Species:	Caenorhabditis elegans

Alignment Length:	491	Identity:	146/491 - (29%)
Similarity:	256/491 - (52%)	Gaps:	12/491 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTSEIISFYKDKTVFITGGTGLLGKVVVEKLL-RATDVKRIYFLVRTKRGEKMEARFESWKKDQV 64
            |...:...|...:|.:|||||.||||:||||| ...|::.||.::||::|:..:.|......|.:
Worm     1 MAFSVRDVYAGSSVLLTGGTGFLGKVIVEKLLWTIDDIQNIYLMIRTRKGKNPQERLSGLLHDPL 65

  Fly    65 FEVLLNKNPLALEKMTPISGDCCAPDLGISETDRRILAAEVQVLIHGAASVRFEEPLEHAVVINT 129
            |..:..:.|.|.:|:..|.||....:||:...|..::...|.|:||.||:|:|:|.|..||.:|.
Worm    66 FNRIRQEKPEAFDKLKAIGGDMMVENLGMDPEDVMLIRDNVNVVIHSAATVKFDEHLRAAVTMNV 130

  Fly   130 RAVRLITQLAKEMRLLESFVHVSTAFSNCVVDQIQERFYPEHLSCPVDKVLDMHNSVSSETFEKM 194
            ...:.|..|..:::.|:..||||||::||...:..|:.|...::  ..|::|..:.:..||..|:
Worm   131 IGTKRIIDLCHQIKDLKVLVHVSTAYANCDRFETTEKIYKSPMA--PQKLVDALSWMDDETLTKI 193

  Fly   195 APALIGKFPNTYTYTKALGEQVIQEEAKGLPVGIFRPAIILSTFKEPVQGWVDGLQGLIAMIFAT 259
            .|.::|..|||||.||||.|..|:.|||.:||.|.||:|:.:.::.|:.||.|.:.|...:..|.
Worm   194 TPKILGLRPNTYTLTKALAESTIETEAKDIPVIIIRPSIVGAMWQGPLPGWTDNINGPTGIFAAV 258

  Fly   260 AYGFVHLLLVNLKVNAPIVPVDYCVNVAIASAVQIAKISKQNKNGPPPIYAFTPSESNLVTYEDL 324
            ..|.:..:..:.:..|.|:|||...|:.||||.....|   |....|.|:. :..|.|.:.:..:
Worm   259 GRGVLTNMCGSSESKADIIPVDIVANMIIASASYRTSI---NTTEIPVIHC-SSGELNPLYWGHI 319

  Fly   325 AGLCYQNGLEVPNAKMIWYPFTHCTRCPYLYNIGILFYHMLPGYLLDIVLRLKGQKPMMIKSYHK 389
            .....|...:.|..:....|.|:..:...|:.|.....|.:|..:.||..||.|::...:|.|.|
Worm   320 VLFLEQFYKKYPMEQCFAVPSTYFHKSRSLFLINYYIKHHIPAAISDISARLIGKRKNNVKLYSK 384

  Fly   390 VHEGMRSLLPFSRKTFTMDMKNTNEMWQSMSPEEKEMFNFDMSTLNWKEYFTCLMDGIRLYLFKD 454
            |.:.:.:|..|:.:.::.:.:...|.::.|:|.:::.:|||:..::|..|....:.||:.:|.|:
Worm   385 VWKMIETLHFFTTRGWSFNARGLPEFFEKMTPADQKEYNFDVRQVDWNSYLFDYVMGIKKFLLKE 449

  Fly   455 LRTPDSVAEGKRILKRFYVLDRILKTVLVTLFGGFI 490
              ..:::...:..|.:..:..:::..:   ::.|||
Worm   450 --NLENLNRSRAHLLKMRIRRQVIAAI---VYAGFI 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10097	NP_001027182.1	PLN02996	1..453	CDD:215538	141/452 (31%)
		FAR-N_SDR_e	12..330	CDD:187547	109/318 (34%)
		Sterile	363..453	CDD:281068	24/89 (27%)
fard-1	NP_001370741.1	FAR-N_SDR_e	13..331	CDD:187547	110/323 (34%)
fard-1	NP_001370741.1	Sterile	358..448	CDD:397244	24/89 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165465
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740