DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10097 and far1

DIOPT Version :9

Sequence 1:	NP_001027182.1	Gene:	CG10097 / 3771756	FlyBaseID:	FBgn0038033	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	XP_017948360.1	Gene:	far1 / 100038270	XenbaseID:	XB-GENE-973776	Length:	518	Species:	Xenopus tropicalis

Alignment Length:	502	Identity:	165/502 - (32%)
Similarity:	261/502 - (51%)	Gaps:	38/502 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IISFYKDKTVFITGGTGLLGKVVVEKLLRA-TDVKRIYFLVRTKRGEKMEARFESWKKDQVFEVL 68
            |..||:.|.|.|||.||.:|||::|||||: .:||.:|.|||.|..:|...|.......::|:.|
Frog     4 IPEFYRGKNVLITGATGFMGKVLLEKLLRSCPNVKAVYVLVRPKASQKPRERVAEMMSCKLFDRL 68

  Fly    69 LNKNPLALEKMTPISGDCCAPDLGISETDRRILAAEVQVLIHGAASVRFEEPLEHAVVINTRAVR 133
            .::.|...:|:..||.:...|:|.:|:.|:.:|...:.::.|.||:|||.|.|..|:.:|..|.|
Frog    69 RDEQPECAQKVIAISSELTQPELDLSKEDQDMLIDCIDIVFHCAATVRFNESLRDAMQLNVIATR 133

  Fly   134 LITQLAKEMRLLESFVHVSTAFSNCVVDQIQERFYPEHLSCPVD--KVLDMHNSVSSETFEKMAP 196
            .:..||::::.||.|:|||||::||...||:|..||.    |||  |:::....:.......:.|
Frog   134 QLLYLAQKIKKLEVFIHVSTAYANCNRKQIEEMVYPP----PVDPKKLIESLEWMDDGLVNDITP 194

  Fly   197 ALIGKFPNTYTYTKALGEQVIQEEAKGLPVGIFRPAIILSTFKEPVQGWVDGLQGLIAMIFATAY 261
            .|||..||||||||||.|.|:|:|...|.:.|.||:|:.:::|||..||:|...|...:..|...
Frog   195 KLIGDRPNTYTYTKALAEYVVQQEGSKLNIAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGK 259

  Fly   262 GFVHLLLVNLKVNAPIVPVDYCVNVAIASAVQIAKISKQNKNGPPP---IYAFTPSESN-----L 318
            |.:..:..:....|.::|||..||..:|:    |..|..|:...|.   :|..|...:|     .
Frog   260 GILRTMRASNNAVADLIPVDVVVNTTLAA----AWYSGVNRYSRPRNILVYNCTTGGTNPFHWGE 320

  Fly   319 VTYEDLAGLCYQNGLEV----PNAKMIWYPFTHCTRCPYLYNIGILFYHMLPGYLLDIVLRLKGQ 379
            |.|..::.. .:|.||.    ||..:        |....||:..|...|..|.:|.|:.||:.|:
Frog   321 VEYHVISTF-KRNPLEQAFRRPNVNL--------TSNHLLYHYWIAVSHKAPAFLYDVYLRITGR 376

  Fly   380 KPMMIKSYHKVHEGMRSLLPFSRKTFTMDMKNTNEMWQSMSPEEKEMFNFDMSTLNWKEYFTCLM 444
            .|.|:|:..::|:.|..|..|:..::..:.:|||.:...:||::|:.||||:..|:|.||.....
Frog   377 SPRMMKTITRLHKAMMLLEYFTSNSWVWNNENTNMLMSQLSPDDKKAFNFDVRQLHWAEYMENYC 441

  Fly   445 DGIRLYLFKDLRTPDSVAEGKRILKRFYVLDRILKTVLVTLFGGFIW 491
            .|.:.|:..:  ....:...::.|.:...:.....|:||.|    ||
Frog   442 MGTKKYVLNE--EMSGLPAARKHLNKLRNIRYGFNTILVVL----IW 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10097	NP_001027182.1	PLN02996	1..453	CDD:215538	158/462 (34%)
		FAR-N_SDR_e	12..330	CDD:187547	116/328 (35%)
		Sterile	363..453	CDD:281068	30/89 (34%)
far1	XP_017948360.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	83	1.000	Domainoid score	I8217
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910