DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment anox and ACBP1

DIOPT Version :9

Sequence 1:	NP_001027085.1	Gene:	anox / 3771728	FlyBaseID:	FBgn0064116	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_200159.1	Gene:	ACBP1 / 835428	AraportID:	AT5G53470	Length:	338	Species:	Arabidopsis thaliana

Alignment Length:	251	Identity:	76/251 - (30%)
Similarity:	115/251 - (45%)	Gaps:	31/251 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SDSD------TDTVDELFHLATEHVA-----KQSNSIGSADLLIFYGYYKQATNGPCKEQSPGLL 55
            ||.|      :..:||.|..||..||     :.|..:.:...|..||.||.||.|||....|..|
plant    81 SDDDDWEGVESTELDEAFSAATAFVAAAASDRLSQKVSNELQLQLYGLYKIATEGPCTAPQPSAL 145

  Fly    56 QLQAKSKWQAWRNLGTMSQSAARQAYVQKLQELQPNW----RSRRN--------PGWVVHSIESV 108
            ::.|::|||||:.||.|....|.:.|:..:.:|.|.|    ..|||        .|.|..|:
plant   146 KMTARAKWQAWQKLGAMPPEEAMEKYIDLVTQLYPAWVEGGSKRRNRSGEAAGPMGPVFSSL--- 207

  Fly   109 PLEDQRLDSE---KTLFDHVKENNLDRLRELLQPSDLVKL-DEHGMALIHWATDRNAVEIIQFLV 169
             :.::..|:|   ..:....:|..::.|.:.::....|.. |..|...:|||.||..:.:.:.||
plant   208 -VYEEESDNELKIDAIHAFAREGEVENLLKCIENGIPVNARDSEGRTPLHWAIDRGHLNVAEALV 271

  Fly   170 RSGASVNQRDAEQQTPLHYAASCGHLEALQCLLELHASLELRDSDGQTCYDVADDE 225
            ...|.||.:|.|.||.||||..|......:.|::..|...::|.||.:..|:.:.|
plant   272 DKNADVNAKDNEGQTSLHYAVVCEREALAEFLVKQKADTTIKDEDGNSPLDLCESE 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
anox	NP_001027085.1	ACBP	10..90	CDD:279259	32/84 (38%)
		ANK	125..231	CDD:238125	31/102 (30%)
		Ank_2	125..212	CDD:289560	26/87 (30%)
		ANK repeat	148..179	CDD:293786	11/30 (37%)
		ANK repeat	181..212	CDD:293786	10/30 (33%)
ACBP1	NP_200159.1	ACBP	113..180	CDD:279259	25/66 (38%)
		ANK	221..324	CDD:238125	30/102 (29%)
		ANK repeat	221..248	CDD:293786	3/26 (12%)
		Ank_2	222..314	CDD:289560	26/91 (29%)
		ANK repeat	250..281	CDD:293786	11/30 (37%)
		ANK repeat	283..314	CDD:293786	10/30 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	60	1.000	Domainoid score	I3848
eggNOG	1	0.900	-	-		E1_COG4281
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12465
Inparanoid	1	1.050	113	1.000	Inparanoid score	I2047
OMA	1	1.010	-	-		QHG54934
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005754
OrthoInspector	1	1.000	-	-		otm3542
orthoMCL	1	0.900	-	-		OOG6_104190
Panther	1	1.100	-	-	LDO	PTHR24119
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1917
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.830