Protein Alignment CG3520 and focad

DIOPT Version :9

• Sequence 1: NP_611792.1
• Gene: CG3520 / 37708
• FlyBaseID: FBgn0034859
• Length: 1204
• Species: Drosophila melanogaster
• Sequence 2: NP_001361602.1
• Gene: focad / 549009
• XenbaseID: XB-GENE-6038577
• Length: 1812
• Species: Xenopus tropicalis
• Alignment Length: 1419
• Identity: 287/1419 - (20%)
• Similarity: 509/1419 - (35%)
• Gaps: 372/1419 - (26%)

  Fly    11 SSVVKLASCLEKIYNKVVESREKQLPEHQIKEIEFLKAQCKHDHMQLSLMSCQTLVRLVDEGVLE 75
            :||:|....|.||         || ..:|...:..|..:|..:::.:....|:.||.||::...:
 Frog    43 ASVLKENVSLGKI---------KQ-SSNQTPALNILWEKCCSNNVVVRTACCEALVLLVEQDHAD 97

  Fly    76 ANGVQNSLLSMLANAGPMHFAIITESILGM-----QLLSLKRRTSSLKGQESYQCTYGLKTQQHP 135
            .:.|.|.:|:::.:||         ::.|:     :||..:.|.:...|:......|.:....||
 Frog    98 FDYVLNGILNLIPSAG---------TVQGLLKCVWRLLYTQARNAEKDGEHKDLGIYKIWNPPHP 153

  Fly   136 LISLLQHSSANMHDVANKIIGICQHYDKSIRDYSIEYLRPVFLYVLCNPQTLHDVKP----IWTC 196
            .||:|::.......:..:|..:.|...:|....::.::.....|:.|.|..|.:...    :...
 Frog   154 FISILENRPDCWPALLQQISTLPQLCHESCPSSNVYFMASFLRYLYCEPSQLQEYSALRIGLRKA 218

  Fly   197 LLNLSGK-------QPEARAL--MQELLAWSKFNNANTCLCTSILVIEAIDHFLQREDHAQSIDL 252
            |:.:|||       :||...|  ..:::.:.:|       ..|..|.||.   |..:|..:|:.|
 Frog   219 LVMVSGKSGSNNPSKPEEHILRIFIDMMGYIQF-------LDSTQVTEAT---LYIKDLCRSLHL 273

  Fly   253 ------GIYQACLIKQLANYGIDPRPSLQC--LLRVLHATREQTKDHYHVLLVLLA-DVLHVLSP 308
                  ....|..::.|.......:.:..|  |:.:|....:...:.:....||:. .:|.:.||
 Frog   274 HPDFWRNELSAVCLQALCACEASLKIAGDCSTLIEILEQNSDLLGESFPTEQVLIGLSLLLLQSP 338

  Fly   309 FYLADLLRIIVFVVVQERCGHEY--ILNMCLDGIIQWMSQTAF---IPAEGLALAHQIVEKVLDP 368
            .....|:..:|..::..|..:.:  |:.:.:..::|.:|.:|.   ...:|.:...|:...:|:
 Frog   339 ASQQKLILKLVMKILSFRGENNFPSIVQVLIMPLLQILSTSALGYCFSDDGGSSREQLATSLLE- 402

  Fly   369 ERSDQEAEVISTKQLK----PAHMRNYHPDIAIAFDLATLVESFDASDNQDVFAFVDALNVKANT 429
              ..|.|:....::|.    |..:..:|..:|...::....:. |.|..:|..:.:.:: :..||
 Frog   403 --MVQNADCSGERRLNDVSLPLPVTTWHCSMAATLNILNKFQD-DHSAARDWLSSISSM-LAPNT 463

  Fly   430 VFCQRLHLFLRALFLSKKPPVDCWFK-IYEVILQIVKVNEGIAYDFLMTYIFKLAHENNPELQLE 493
            .....:.|.|..|.:.:.   |...: :.:||..:.|.:.......:...:.:|.|...||...:
 Frog   464 QVPVNVSLLLSFLLIRES---DYGLRNVLKVITDVSKADSSQVPYLVPVLMLRLGHSLAPESSRD 525

  Fly   494 LLRGLASFAVCKDNVPMILNTIRNLSTEN--GTFCVDLYVRLWRVERRTYPFLLKQIA----QPL 552
            :|..|.:....|..|..||...:.|.:.:  ....:.|...||..:.|.||.|.|.:|    |.|
 Frog   526 ILYTLPTLGTHKVCVAQILRVFQMLGSTSKLQPIALRLMTSLWEKQDRIYPELQKMMALCDTQSL 590

  Fly   553 -PDNDKRWELQIARNHAMREICQEKPTLHGTELLPHLSNTLNHSSDEAGDLAT--SLALDAIYSL 614
             ...|..||..:|:...:|:||:::|..||.::|..::..| |...:| |.||  :|||..:::|
 Frog   591 ATGKDTLWEKMLAKAATVRDICRQRPYQHGADMLAAITQVL-HECTKA-DQATPAALALQGLHAL 653

  Fly   615 CDSHTVNIASTWQALGSKFRNEMRPQTLKSLYRLFGLVPMLKTPTLEYEKLADDALEHLWQAISR 679
            |.:..|:|.|.|.||.||...|.||..||.|:.||.|||.|...|.||:|...:.:..||:  ..
 Frog   654 CQAEVVDIRSAWNALSSKLSCETRPLVLKVLHELFALVPSLTVDTEEYQKFKTEIIGILWR--HT 716

  Fly   680 PGTDAAQVRNALVALRNYEPGVTLNLRHIPAQFRFEIVGGGVGAGGAGGREVVDLQQE------- 737
            ...|...:.:|..:|..:|.. ..::.|||.|.|.|:          ..::..||..|
 Frog   717 QSKDLNVMVSAYKSLCEFEAD-EHSILHIPEQARPEV----------APKDESDLASEEEEKETD 770

  Fly   738 -TVPGEVWVQLLQKIRPECGDAAADLISHHIDSEINAFRSGVY---------RLPEGKP------ 786
             ::||..:::|:.........|....:|..:..|::....|:|         |..:||.
 Frog   771 ISIPGSSYIKLMALTPVSVLPALEAFLSSLVKQEMSRMPRGIYHTALRGGNIRSDQGKTIAGVPN 835

  Fly   787 ------EPRKLVGL---FATSPL-------------RAVTNYLVSQARFGDY------------- 816
                  |..|..||   .|...|             |.:..:|.|:.|  .|
 Frog   836 FMLKMYEKNKQPGLKPGLAAGMLLCYDLPIQTDKDGRPINRFLASRGR--SYQQMLTALINEVNI 898

  Fly   817 ----------VPEPY----------------------------------------------AVTF 825
                      :|:.:                                              |:|.
 Frog   899 QSSEWHRSILLPQSWLGFMTRTYHAVLQGRQAELEMQLKHGKDDPQELQYKTFTAWLWVRDALTD 963

  Fly   826 ALRSLSKNFP----------------------------------KP--IPPLDWSCLTS------ 848
            .:|...|:.|                                  :|  :|...|..:..
 Frog   964 VIRCAVKDSPVVKGNSLLALTGLAVAVSKYESSLPSETEGAPEIEPDILPTSAWITMVLDTLLST 1028

  Fly   849 --------------FFHLSFDARKYCIIIAKNQAVNSGTAKRLLENFLIDFEPNCFEEDLLLLFS 899
                          |.|.|:.......:||::.|   .||..||...|:.......|:.|.:|.:
 Frog  1029 VDNHYQPKGRIFPWFQHKSYSGENTASVIARSCA---ATALSLLVPVLVVSNKEKVEDILNILTA 1090

  Fly   900 LLP-------------EIANSVSLQILKNFAEKVAVYCFKESQIN-------DFVEGCLFEKFLE 944
            .||             .:..:|.:.|.:.|.|||:....:  |:|       |.:|.|.|::.||
 Frog  1091 RLPGKPLADDSQSLQIHMGLAVGMFISRLFEEKVSDVSGR--QMNLLMMRSLDALESCCFDQSLE 1153

  Fly   945 -------SVKYIFTGNCDIPEV---LDVFTLIVERYMDSMNLDSRLFER----YTEVVATL---- 991
                   .|..:.:..|...:.   :.|.|.:.:.|| :::.|....|:    |:....|:
 Frog  1154 YNMGCILGVGLVLSFMCQSSQTDSQVHVSTTLRKFYM-ALSEDKSRTEQEGLSYSLACGTVSAFS 1217

  Fly   992 -----------HPNAIDGLTTPANWWETPVGKLKKATIIRCYLV--------LYNEKLPNPLKWL 1037
                       |.|.: .|.|..| .:||...|...:|:....:        |.|..||   .|:
 Frog  1218 AGILSAEEAEEHMNKL-RLMTEQN-QQTPGLALALGSIVHGLSICGHGKAEDLNNRLLP---AWM 1277

  Fly  1038 TPIIDAYEKRAEERPFFYRHLAAT--LYAFESDE-----------HSSNWIAEMFLEIQMLLAEA 1089
            ..::      ||..|...| |||.  |.|....|           |||.:              .
 Frog  1278 KILL------AEGCPTMQR-LAAINGLVALVGSESALIQLKSEVIHSSQF--------------Q 1321

  Fly  1090 SNKEKVNRALYLLDIFILAVDVLSGCAVLLGSVDVVATDDKQRLALFPESLQYL 1143
            |...:|.||:..:..|..|:.:.:..|.:||.:.:.:....|.....|....||
 Frog  1322 SKLNEVIRAITQIVSFSGAIGLQTNAAWILGHLHLSSISSSQSRTSIPPDFSYL 1375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3520	NP_611792.1	DUF3730	475..694	CDD:289307	72/227 (32%)
		DUF3028	<798..1201	CDD:288127	95/554 (17%)
focad	NP_001361602.1	DUF3730	507..731	CDD:372168	72/227 (32%)
		Focadhesin	1230..1812	CDD:371426	39/172 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I6537
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	196	1.000	Inparanoid score	I3708
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D104158at33208
OrthoFinder	1	1.000	-	-		FOG0007517
OrthoInspector	1	1.000	-	-		oto103511
Panther	1	1.100	-	-	LDO	PTHR16212
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.070