Protein Alignment CG3520 and Focad

DIOPT Version :10

• Sequence 1: NP_611792.1
• Gene: CG3520 / 37708
• FlyBaseID: FBgn0034859
• Length: 1204
• Species: Drosophila melanogaster
• Sequence 2: NP_001414624.1
• Gene: Focad / 313346
• RGDID: 1311849
• Length: 1798
• Species: Rattus norvegicus
• Alignment Length: 1193
• Identity: 259/1193 - (21%)
• Similarity: 449/1193 - (37%)
• Gaps: 253/1193 - (21%)

  Fly    11 SSVVKLASCLEKIYNKVVESREKQLPEHQIKEIEFLKAQCKHDHMQLSLMSCQTLVRLVDEGVLE 75
            ::|:|.....|||:...          :|...:..|..:...|::.:.....:.||.||.:|..|
  Rat    26 AAVLKEHGASEKIHQST----------NQTAALNLLWEKSCSDNVVVRTACSEGLVALVAQGHAE 80

  Fly    76 ANGVQNSLLSMLANAGPMHFAIITESILGMQLLSLKRRTSSLKGQESYQCTYGLKTQQHPLISLL 140
            .:.|.|.:|:::.:|..|...|  :::  |:||.::.......|.:..|..|.::....|||::|
  Rat    81 FSYVLNGILNLIPSARNMSGLI--KAL--MKLLQMQASREGQGGAKDLQDLYSIRNPPQPLITVL 141

  Fly   141 QHSSANMHDVANKIIGICQHYDKSIRDYSIEYLRPVFLYVLCNPQTLHDVKPIWTCLLNL----S 201
            :|.......:..::....|...:......::.:.|...|:.|.|..|.:...:...||.:    .
  Rat   142 EHRPDCWPLLLQQLTAFFQQCPERSEASCVQIMAPFLWYLYCEPSQLQEYAKLRLSLLKVLLQPR 206

  Fly   202 GKQPEAR--ALMQELLAWSKFNNANTCLCTSILVIEAIDHFLQREDHAQSIDLGIY--------- 255
            |...||:  .|.|::|.          ||.:::..      ||.:|..|:.::.::
  Rat   207 GVCEEAQPSVLEQQILQ----------LCCNMVPC------LQMKDLMQTTEMTLFVEEVYLSLL 255

  Fly   256 --QACLIKQLANYGIDPRPSLQCLLRV-LHATREQTKDHYHVLLVLLADVLHVLSPFYLADLLRI 317
              .|...:||....:    .|.|:..| |..|.|.:.     |:.||...:.:|...:...|:.|
  Rat   256 RHPAFWKRQLTQLTV----QLLCICEVSLKTTGECSS-----LIQLLERSVELLGEDFPVKLVII 311

  Fly   318 -IVFVVVQERCGHEY-ILNMCL------DG-------------IIQWMSQTAFIPAEGLALAHQI 361
             |..:::|.....:. :||:.|      :|             ::|.:|.||.  .:.||...:
  Rat   312 GIALILLQTPASQQKPVLNLTLKLLSLTEGQRIPKASLLLLVPLLQILSSTAL--EDCLATGEE- 373

  Fly   362 VEKVLDPERSDQEAEVISTKQLKPAHMRNYHP-DIAIAFDLATLVESF-----------DASDNQ 414
                 .|.|......::...| :..|..:.|. ...:||.::::..|.           :||...
  Rat   374 -----GPSRQQLALSLLEVLQ-RECHGDDRHTISCRLAFPVSSMYGSVFTACRILEVMGEASAAS 432

  Fly   415 DVFAFVDALNVKANTVFCQRLHLFLRALFLSKKPPVDCWFKIYEVILQIVKVNEGIAYDFLMTYI 479
            |..|.|::| :.|.||...  |:||....|..:.......:|.:|..|:.:.:.......:...:
  Rat   433 DWLAAVESL-LPATTVIPP--HVFLLLAHLLVEDGGQNLQQILKVTTQLAQADSSQVPHLIPVLM 494

  Fly   480 FKLAHENNPELQLELLRGLASFAVCKDNVPMILNTIRNLSTENGTFCVD--LYVRLWRVERRTYP 542
            |||....:|.....:|..|.:..|.|..|..||..|:.|.|......|.  |...||..:.|.||
  Rat   495 FKLGRPLDPVSYNHILYTLPTLGVHKVCVGQILRVIQLLGTTPRLRAVTLRLLTSLWEKQDRVYP 559

  Fly   543 FLLKQIA-QPLPD----NDKRWELQIARNHAMREICQEKPTLHGTELLPHLSNTLNHSS--DEAG 600
            .|.:.:| ...|.    .:.:||..||:..::|:||:::|..||.::|..:|..||..:  |:|.
  Rat   560 ELQRFMAMSDAPSLSVGKELQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQAS 624

  Fly   601 DLATSLALDAIYSLCDSHTVNIASTWQALGSKFRNEMRPQTLKSLYRLFGLVPMLKTPTLEYEKL 665
            ..|  |.|..:::||.:..|.|.|||.||..|...:|||..||:|..||.|||.|...|:|||..
  Rat   625 PAA--LVLQGLHALCQAEVVCIRSTWNALSPKLSCDMRPLILKTLSELFSLVPSLTVNTVEYENF 687

  Fly   666 ADDALEHLWQAISRPGTDAAQVRNALVALRNYEPGVTLNLRHIPAQFRFEI-VGGGVGAGGAGGR 729
            ....|..||  ......|......|..:|.::..| ...:.|:|.:.|.|: |...:..     .
  Rat   688 KVQVLTFLW--THTQNKDPIVASAAYKSLSHFSAG-EHTILHLPEKIRPEMPVPDELDE-----E 744

  Fly   730 EVVDLQQETVPGEVWVQLLQKIRPECGDAAADLISHHIDSEINAFRSGVYRLPEGKPEPRKLVGL 794
            |.|||   ::||..:::||....|....|..:..:..:..|:.....|:|.        ..|.|.
  Rat   745 ESVDL---SIPGSCYLRLLTITAPSILPALEEFFTSLVRQEMVNMPRGIYH--------SALKGG 798

  Fly   795 FATSPLRAVTNYLVSQARFGDYVPEPYAVTFALRSLSKN-FPKPIPPLDWSCLTSFFHLSFDARK 858
            ..:...:.|..           :|     .|.|::...| .|...|.|....|
  Rat   799 VCSDQGKTVAG-----------IP-----NFILKTYETNKQPGLKPGLAGGML------------ 835

  Fly   859 YCIIIAKNQAVNSGTAKRLLENFLIDFEPNCFEEDLLLLFS-------------LLPE------- 903
            :|..:|..|:.:.....||:.:     ....|::..|.|..             .||:
  Rat   836 FCYDVAMYQSKDGKPLNRLMAS-----RGRTFKQTTLALVHEVHVQLSEWHRAIFLPQAWLAYMT 895

  Fly   904 ----------IAN-SVSLQILKNFAEKVAVYCFKESQINDFVEGCLFEKFLESV---KYIFTGNC 954
                      ||. .:.||..|...|:|.   :|.|....:|...|.::..::.   ..:..||.
  Rat   896 RAYHAILQGRIAELELQLQHGKEGPEEVQ---YKRSTAWLWVRDMLTDEITKTAAKESPVVKGNA 957

  Fly   955 DIPEVLDVFTLIVERYMDSMNLDSRLFERYTEVVATLHPNAIDGLTTPANWWETPVGKLKKATII 1019
            .:  .|....::|.::..|::.:|       :.|..:.||.:     |...|.:.|
  Rat   958 LL--ALSSLAVVVSKHEASLSSES-------DGVLEVQPNFL-----PVKEWVSMV--------- 999

  Fly  1020 RCYLVLYNEKLPNPLKWLTPIIDA-YEKRAEERPFFYRHLAATLYAFESDEHSSNWIAE----MF 1079
                          |..:..|:|: |..|.:....||       :...|.|::::.||.    ..
  Rat  1000 --------------LNTVLVIVDSHYHPRGQLFTCFY-------HKSYSGENTASAIARSAAATA 1043

  Fly  1080 LEIQMLLAEASNKEKVNRALYLL 1102
            |.:.:.:...|.||||...|.:|
  Rat  1044 LSLLVPVFIISCKEKVEEILNML 1066

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3520	NP_611792.1	DUF3730	475..694	CDD:463619	74/227 (33%)
Focad	NP_001414624.1	None