Protein Alignment CG3530 and Mtmr2

DIOPT Version :9

• Sequence 1: NP_726322.1
• Gene: CG3530 / 37707
• FlyBaseID: FBgn0028497
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: XP_036011299.1
• Gene: Mtmr2 / 77116
• MGIID: 1924366
• Length: 718
• Species: Mus musculus
• Alignment Length: 644
• Identity: 229/644 - (35%)
• Similarity: 352/644 - (54%)
• Gaps: 82/644 - (12%)

  Fly    20 TSALRLSFDNISPETEEPPDGNKRLWGVPVPPFVSEKVVSWIEEEFNEAPVFYNGNSVLKKVENV 84
            :.::..|.||.||:.....:.||          ::|.          |.|....|.::....::|
Mouse   115 SDSISTSADNFSPDLRVLREANK----------LAEM----------EEPALLPGENIKDMAKDV 159

  Fly    85 RMIDRYNTKNPTVGTLYLTATHLIF--VEPDSNKETWILHMH---VASIEKL-PLSTTGS---PL 140
            ..|..:.  ....|||.:|:..|.|  :|.|   ..::|...   ::.:||: ..|:.|.   .|
Mouse   160 TYICPFT--GAVRGTLTVTSYRLYFKSMERD---PPFVLDASLGVISRVEKIGGASSRGENSYGL 219

  Fly   141 LIRCKTFLSVTFV-IPKDSECHDVYTSLLKLFQPVSIN-KLYCFNYQPNKDDFPKNAGWDYFKLE 203
            ...||...::.|. .|:......::.:|:|...|||.. .|:.|.|   |:.||:| ||..:...
Mouse   220 ETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNGLPLFAFEY---KEVFPEN-GWKLYDPL 280

  Fly   204 AEFKHMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLH-NN 267
            .|::...:|||:|.:..:||:||||||||..:.||.......|...:.|||:||:|||:::| .:
Mouse   281 LEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPES 345

  Fly   268 KASICRCSQPLSGFSA-RCLEDEQMLEAIRKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAF 331
            :|::.|||||:.|.|. |..|||:.|:||..:|:.:..:::.|.||.:||:||:|.|.|||:|..
Mouse   346 QATVTRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDA 410

  Fly   332 YENIKFHFLGIENIHVQRASLQKVLEACEQKSPTM--SAFINALESSGWLKHIRSILDTSSFIAN 394
            |:|.:..||.|.||||.|.||:|:.|..   .||:  :.:::.|||:.||:||:.||..:..||:
Mouse   411 YQNAELVFLDIHNIHVMRESLRKLKEIV---YPTIEETHWLSNLESTHWLEHIKLILAGALRIAD 472

  Fly   395 AVDKG-VSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGH--- 455
            .|:.| .|||||||||||||||:.|||.|||:.|||||:||:.|:||:||:|||:|..|.||
Mouse   473 KVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDK 537

  Fly   456 IQTDAREVSPIFTQFLDCTWQ-------LMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEK 513
            ...|| :.||:|.||:||.||       |..|...||||||.||:.:.||::||.||||:.|.|:
Mouse   538 NHADA-DRSPVFLQFIDCVWQMTRQFVVLNLQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQ 601

  Fly   514 DRLDLKLAERTFSLWGYMANHLNEYINPLYKPNVDEAIKANLAPQCIKFWRGMYSRFESGIHPRE 578
            .|....|.::|.|||.|:.:.|.::.||||....:..:....:.:.::.|.|.|.|:...:.|:|
Mouse   602 QRGKENLPKKTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQE 666

  Fly   579 PLGDVLLDSKEHCNSLEDHVQHLTKRIASFKNYISKSAKKLQDATSAPGKVNKELSSNE 637
            |:                |.::  |.:.:.:..:.:..::||...|     |:..||:|
Mouse   667 PI----------------HSRY--KELLAKRAELQRKVEELQREIS-----NRSTSSSE 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3530	NP_726322.1	PH-GRAM_MTMR6-like	78..173	CDD:270030	22/104 (21%)
		Myotub-related	179..514	CDD:284109	165/349 (47%)
		FYVE_MTMR_unchar	693..753	CDD:277277
Mtmr2	XP_036011299.1	PH-like	141..255	CDD:418428	26/128 (20%)
		Myotub-related	270..603	CDD:399535	160/337 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846031
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D824298at2759
OrthoFinder	1	1.000	-	-		FOG0000303
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1956
SonicParanoid	1	1.000	-	-		X213
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.880