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Protein Alignment CG3530 and MTMR8

DIOPT Version :9

Sequence 1:	NP_726322.1	Gene:	CG3530 / 37707	FlyBaseID:	FBgn0028497	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	NP_060147.2	Gene:	MTMR8 / 55613	HGNCID:	16825	Length:	704	Species:	Homo sapiens

Alignment Length:	531	Identity:	291/531 - (54%)
Similarity:	381/531 - (71%)	Gaps:	5/531 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 KVENVRMIDRYNTKNPTVGTLYLTATHLIFVEPD--SNKETWILHMHVASIEKLPLSTTGSPLLI 142
            |||||:::|||.:|.|..|.|||||||||:||..  :.|||||...|:|::||||:::.|.||.:
Human     8 KVENVKLVDRYVSKKPANGILYLTATHLIYVEASGAARKETWIALHHIATVEKLPITSLGCPLTL 72

  Fly   143 RCKTFLSVTFVIPKDSECHDVYTSLLKLFQPVSINKLYCFNYQPNKDDFPKNAGWDYFKLEAEFK 207
            |||.|....||:..|..||:||.|||||.||.....||.|:|.|......:.:||......::|.
Human    73 RCKNFRVAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSSKEMRESGWKLIDPISDFG 137

  Fly   208 HMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLH-NNKASI 271
            .|.:||..||:...|..||:|.|||.:|.|||..|...::.||:||||.|:|||:||: .|.|:|
Human   138 RMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAI 202

  Fly   272 CRCSQPLSGFSARCLEDEQMLEAIRKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYENIK 336
            ||||||||||..||::||.:||||.:||..:.:||||||||::|||||||||||||||..|.||:
Human   203 CRCSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVVDTRPKLNAMANRAAGKGYENEDNYANIR 267

  Fly   337 FHFLGIENIHVQRASLQKVLEACEQKSPTMSAFINALESSGWLKHIRSILDTSSFIANAVD-KGV 400
            |.|:|||||||.|:||||:||.||.|:||||.|::.|||||||:||::|:|...||..||. :..
Human   268 FRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWLRHIKAIMDAGIFITKAVKVEKA 332

  Fly   401 SVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHIQTDAREVSP 465
            ||:|||||||||||||||:|.::|:|:|||.||...||||:|::.|||||:||||:..|::||||
Human   333 SVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSP 397

  Fly   466 IFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGY 530
            ||||||||.||||.|...||||||.|||.:||||.|||||.|:|||:|||.||::.|:|.|:|.:
Human   398 IFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPF 462

  Fly   531 MANHLNEYINPLYKP-NVDEAIKANLAPQCIKFWRGMYSRFESGIHPREPLGDVLLDSKEHCNSL 594
            :.....::.|||||. .:...:..:..|..|:||.|||:||:.|:.|::.:.:.||:.|:....|
Human   463 LVQRKPDFRNPLYKGFTMYGVLNPSTVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAML 527

  Fly   595 EDHVQHLTKRI 605
            |..|..|.|::
Human   528 ETDVHELEKKL 538

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.