Protein Alignment CG3530 and mtm1

DIOPT Version :9

• Sequence 1: NP_726322.1
• Gene: CG3530 / 37707
• FlyBaseID: FBgn0028497
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001015828.1
• Gene: mtm1 / 548545
• XenbaseID: XB-GENE-1002030
• Length: 602
• Species: Xenopus tropicalis
• Alignment Length: 593
• Identity: 221/593 - (37%)
• Similarity: 333/593 - (56%)
• Gaps: 62/593 - (10%)

  Fly    63 EEFNEAPVFYNGNSVLKKVENVRMIDRYNTKNPTVGTLYLTATHLIF----VEPDSNKETWILHM 123
            |:.:|.|.. .|.:::...:.:.|...|   .|..|.:::|...|.|    :||       ::..
 Frog    29 EQNDEIPCL-PGEALITDKDVIYMCPFY---GPVKGRIHVTNYKLYFKGEEMEP-------LISF 82

  Fly   124 HV-----ASIEKL-PLSTTGS---PLLIRCKTFLSVTFVIPKDSECH---DVYTSLLKLFQPVSI 176
            .|     |.|||: ..|:.|.   .|.|.||...::.|.:.:  |.|   .::..|.|...|:|
 Frog    83 SVPLGVIARIEKMGGASSRGENSYGLDITCKDMRNLRFALKQ--EVHSRKQIFEDLTKYAFPLS- 144

  Fly   177 NKLYCFNYQPNKDDFPKNAGWDYFKLEAEFKHMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEA 241
            :.|..|.:| |::.||:| ||..:....||:...:||..|.:..:|:.||||||||..:.||..|
 Frog   145 HGLLLFAFQ-NEEKFPEN-GWAVYDAMTEFRRQGLPNGQWRITFINKNYELCDTYPPLLVVPYSA 207

  Fly   242 TTLMLISSSRFRSKGRLPVLTYLH-NNKASICRCSQPLSGFSA-RCLEDEQMLEAIRKTNSNTDY 304
            :...|...:.|||:.|:|||::|| .|:::|.||||||.|.|. |..:||:.|:.||.||..|..
 Frog   208 SEEDLKKVAAFRSRNRIPVLSWLHPENQSAIMRCSQPLVGMSGKRNKDDERYLDIIRDTNGQTSK 272

  Fly   305 MYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACEQKSPTMSAF 369
            :.:.|.||.:||:||:|.|.|||:|..|.|.:..||.|.||||.|.||:| |:.....:...|.:
 Frog   273 LTIYDARPNVNAVANKATGGGYESEDAYPNAELVFLDIHNIHVMRESLKK-LKDIVYPNVEESHW 336

  Fly   370 INALESSGWLKHIRSILDTSSFIANAVDKG-VSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKG 433
            :::|||:.||:||:.:|..:..:|:.|..| .|||||||||||||||:.|||.|||:.|||||.|
 Frog   337 LSSLESTHWLEHIKLVLTGAIQVADKVASGKSSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIVG 401

  Fly   434 FQALIEKDWLAFGHKFSERCGH---IQTDAREVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLIL 495
            |:.|::|:|::||||||.|.||   ...|| :.||||.||:||.||:..|...||||||.||:.:
 Frog   402 FEVLVQKEWISFGHKFSSRIGHGDKNHADA-DRSPIFLQFIDCVWQMSKQFPTAFEFNEHFLITV 465

  Fly   496 HDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPNVDEAIKANLAPQCI 560
            .||::||:||||:.|||..|...|:.|:|.|||..:::..::|.||.|...::..:....:.:.:
 Frog   466 LDHLYSCRFGTFLYNCENIRDKEKVREKTQSLWSLISSEKSKYTNPFYTKELNRVLYPVASMRHL 530

  Fly   561 KFWRGMYSRFESGIHPREPLGDVLLDSKEHCNSLEDHVQHLTKRIASFKNYISK-------SAKK 618
            :.|...|.|:...|..::|            |.:|.....|   :|...:|:.:       ::.|
 Frog   531 ELWVNYYIRWNPRIRQQQP------------NPVEQRYMEL---LALRDDYVRRLEELQITNSPK 580

  Fly   619 LQDATSAP 626
            :..:|::|
 Frog   581 MNSSTTSP 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3530	NP_726322.1	PH-GRAM_MTMR6-like	78..173	CDD:270030	25/110 (23%)
		Myotub-related	179..514	CDD:284109	166/340 (49%)
		FYVE_MTMR_unchar	693..753	CDD:277277
mtm1	NP_001015828.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32		1/2 (50%)
		PH-like	43..142	CDD:388408	25/110 (23%)
		Myotub-related	150..485	CDD:368997	165/338 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	574..602		3/15 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D824298at2759
OrthoFinder	1	1.000	-	-		FOG0000303
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1956
SonicParanoid	1	1.000	-	-		X213
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950