Protein Alignment Mtmr6 and mtmr1b

DIOPT Version :10

• Sequence 1: NP_726322.1
• Gene: Mtmr6 / 37707
• FlyBaseID: FBgn0028497
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: XP_073790617.1
• Gene: mtmr1b / 541517
• ZFINID: ZDB-GENE-050327-48
• Length: 659
• Species: Danio rerio
• Alignment Length: 663
• Identity: 222/663 - (33%)
• Similarity: 349/663 - (52%)
• Gaps: 95/663 - (14%)

  Fly     1 MDITRFMNKFNEIERQLSPTSALRLSFDNISPETEEPPDGNKRLWGVPVPPFVSEKVVSWIEEEF 65
            |::..|:  .:...:|.:|:||||              :|||                   :.:.
Zfish    56 MEVKGFL--LDSDPQQTAPSSALR--------------EGNK-------------------QAQM 85

  Fly    66 NEAPVFYNGNSVLKKVENVRMIDRYNTKNPTVGTLYLTATHLIF---------VEPDSNKETWIL 121
            .|||.. .|.::...|::|..|..::  ....|||.:|...|.|         ::..|....::|
Zfish    86 EEAPRI-PGETIKAIVKDVMYICPFS--GVIRGTLTITDFKLYFKSLTRVNSLLKLSSGDSPFVL 147

  Fly   122 HMH---VASIEKLPLSTTGSP---LLIRCKTFLSVTFVIPKDSECH-DVYTSLLKLFQPVSIN-K 178
            .::   |:.:|.:.:.:.|..   |.|.||...:..|...|:.:.: :::..|.|...|:|.| .
Zfish   148 DVNLGAVSRLESIAVQSHGDDTQGLEIVCKDLRTPRFAYKKEGQSNLEMFKILSKYAFPLSHNLP 212

  Fly   179 LYCFNYQPNKDDFPKNAGWDYFKLEAEFKHMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATT 243
            |:.|.|   ::.||:: ||..:...||:|...:|||:|.:..:|..||:|:|||..:.:|...|.
Zfish   213 LFAFKY---RETFPED-GWKIYDPVAEYKRQGLPNESWIISKVNSGYEVCETYPALLVLPSNVTE 273

  Fly   244 LMLISSSRFRSKGRLPVLTYLH-NNKASICRCSQPLSGFS-ARCLEDEQMLEAIRKTNSNTDYMY 306
            ..|...:.||:|.|.|||:::| .::|:|.||.||..|.| .||.|||:.|:.|...|:.:..:.
Zfish   274 DELKRVAAFRAKRRFPVLSWIHPESQAAIVRCGQPQVGPSDRRCREDERYLQTILDANAQSHKLC 338

  Fly   307 VVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACEQKSPTMSAFIN 371
            :.|.|....|..|:|...|||||:||.|::.:||.|.||||.|.||:|:.|...........|.|
Zfish   339 IFDARQSTVADTNKAKDGGYENESFYINVELNFLEIPNIHVMRESLRKLKEVVYPAIDQQHWFSN 403

  Fly   372 ALESSGWLKHIRSILDTSSFIANAVDKG-VSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQ 435
             ::::.||:::|.:|..:..||:.::.| .|||||||||||||||:.|||.|||:.:||::||||
Zfish   404 -VDATHWLEYVRLLLAGAVRIADRIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDAHYRSLKGFQ 467

  Fly   436 ALIEKDWLAFGHKFSERCGHIQTDAR----EVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLILH 496
            .|:||:||:|||:|:.|.||  .|..    |.||:|.||:||.||:..|...||||||.||:.:.
Zfish   468 VLLEKEWLSFGHRFASRVGH--GDGNHANSERSPLFVQFIDCVWQMTRQFPSAFEFNELFLITVL 530

  Fly   497 DHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPNVDEAIKANLAP-QCI 560
            ||:.||.||||:.|.|::|:..::..:|.|||.|:.:.:.|:.|||| .|.:..:...:|. :.:
Zfish   531 DHLFSCLFGTFLYNSEQERVSKEVYNKTVSLWSYVNSQIEEFTNPLY-VNYEHHVLYPIASLRHL 594

  Fly   561 KFWRGMYSRFESGIHPREPLGDVLLDSKEHCNSLEDHVQHLTKRIASFKNYISKSAKKL-QDATS 624
            :.|...|.|:...:.|:.|:...|                  |.:...|:.:.|..:.| |||.|
Zfish   595 ELWVSYYVRWNPRMRPQVPIHQSL------------------KELLVLKSELQKRVEDLKQDAAS 641

  Fly   625 APGKVNKELSSNE 637
                 :..|||:|
Zfish   642 -----SNSLSSSE 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtmr6	NP_726322.1	PH-GRAM_MTMR6-like	78..173	CDD:270030	22/110 (20%)
		PTP-MTMR6-like	202..501	CDD:350380	136/305 (45%)
		FYVE_MTMR_unchar	693..753	CDD:277277
mtmr1b	XP_073790617.1	None