Protein Alignment Mtmr6 and mtm

DIOPT Version :10

• Sequence 1: NP_726322.1
• Gene: Mtmr6 / 37707
• FlyBaseID: FBgn0028497
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_523489.1
• Gene: mtm / 33845
• FlyBaseID: FBgn0025742
• Length: 619
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 211/560 - (37%)
• Similarity: 323/560 - (57%)
• Gaps: 57/560 - (10%)

  Fly    93 KNPTVGTLYLTATHLIFVE-PDSNKETWI-----LHMHVASIEKLPLSTTGSP----LLIRCKTF 147
            :.|..|.|.:|...|.|.. |..::|..:     |.: :|.:||:..:|:...    :.|.||..
  Fly    69 RGPVFGALTITNYRLYFRSLPLRDQEPPVVVDVPLGV-IARVEKIGGATSRGENSYGIEIFCKDM 132

  Fly   148 LSVTFVIPKDSEC-HDVYTSLLKLFQPVSIN-KLYCFNYQPNKDDFPKNAGWD---YFKLEAEFK 207
            .::.|...:.:.. ..|:..|.....|:|.: :|:.|.:.. .:....|.|||   .::..||.:
  Fly   133 RNLRFAHKQQNHSRRTVFEKLQANAFPLSYSGRLFAFAHAA-ANSVNGNGGWDGWAVYEPLAELR 196

  Fly   208 HMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLH-NNKASI 271
            .:.|||:.|....:||.|.:||:||....|||.|:...|...::|||:.|||||:::: ..:|:|
  Fly   197 RLGVPNDMWRATKLNESYAICDSYPAVWAVPKAASDDFLRRVAQFRSRCRLPVLSWMNPRTQATI 261

  Fly   272 CRCSQPLSGFSA-RCLEDEQMLEAIRKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYENI 335
            .||||||.|.|. |..:||..|..|.:.|:.:|.:.::|.||..||:||:|.|.|||:|..|:|:
  Fly   262 TRCSQPLVGVSGKRNSDDEAYLSFIMEANAQSDKLTIMDARPSANAIANKAKGGGYESEDAYKNV 326

  Fly   336 KFHFLGIENIHVQRASLQKVLEACEQKSPTM--SAFINALESSGWLKHIRSILDTSSFIANAVD- 397
            :.:||.|.||||.|.||:||.|||   .||.  |.:..|::::.||||||.||..:..|.:.|:
  Fly   327 EINFLDIHNIHVMRESLRKVKEAC---FPTTDDSKWQTAIDNTLWLKHIRCILAGAVRIVDKVET 388

  Fly   398 KGVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGH---IQTD 459
            ...|||||||||||||||:.:|:.|:|:|:|||::||:.||||:||:|||||.:|.||   ..:|
  Fly   389 MSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHKFQQRIGHGDNKHSD 453

  Fly   460 AREVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERT 524
            | :.||:|.||:|..||:..|.:.||||||.||:.:.||::||:||||:.|.|.:|:...|..:|
  Fly   454 A-DRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTEAERVAEDLKHKT 517

  Fly   525 FSLWGYMANHLNEYINPLYKPNVDEAIKANLAP----QCIKFWRGMYSRFESGI--------HPR 577
            .|||.::.:.|::|:|||: |:.....:..|.|    :.::.|:|:|.|:..|:        ..|
  Fly   518 TSLWTHINSSLDQYLNPLF-PSFTHGAELVLRPIASVRSVRLWKGLYCRWNPGLCAPQHGCQRTR 581

  Fly   578 EPL----------GDVLLDSKEHCNSLEDHVQHLTKRIAS 607
            |.|          .::.|.|....||::     .|.|:||
  Fly   582 ELLSKQDQLFKLVNELRLKSNNRSNSMQ-----TTTRLAS 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtmr6	NP_726322.1	PH-GRAM_MTMR6-like	78..173	CDD:270030	19/90 (21%)
		PTP-MTMR6-like	202..501	CDD:350380	146/306 (48%)
		FYVE_MTMR_unchar	693..753	CDD:277277
mtm	NP_523489.1	PH-GRAM_MTMR2_insect-like	57..159	CDD:270164	19/90 (21%)
		Myotub-related	184..509	CDD:461958	155/328 (47%)