Protein Alignment Mtmr6 and Mtmr1

DIOPT Version :10

• Sequence 1: NP_726322.1
• Gene: Mtmr6 / 37707
• FlyBaseID: FBgn0028497
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: XP_063133525.1
• Gene: Mtmr1 / 317296
• RGDID: 1306569
• Length: 689
• Species: Rattus norvegicus
• Alignment Length: 659
• Identity: 228/659 - (34%)
• Similarity: 345/659 - (52%)
• Gaps: 85/659 - (12%)

  Fly    13 IERQLSPTSALRLSFDNIS--------PETEE--------PP---------DGNKRLWGVPVPPF 52
            |..|:|.:    ::.:|:|        |:|.|        |.         ||||.
  Rat    65 ISTQMSGS----VTSENVSRDYKVFRRPDTRELQEEHNGYPSAAEADQALRDGNKL--------- 116

  Fly    53 VSEKVVSWIEEEFNEAPVFYNGNSVLKKVENVRMIDRYNTKNPTVGTLYLTATHLIF--VEPDSN 115
                      .:..|||:| .|.|:...|::|..|..:  .....|||.:|...:.|  ||.|.:
  Rat   117 ----------AQMEEAPLF-PGESIKAIVKDVIYICPF--AGAVSGTLTVTDFKMFFKNVERDPH 168

  Fly   116 KETWILHMH---VASIEKLPLSTTGS---PLLIRCKTFLSVTFVIPKDSECH-DVYTSLLKLFQP 173
               :||.:.   ::.:||:...:.|.   .:.|.||...::.....::.:.. .::.:|.|...|
  Rat   169 ---FILDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRNLRLAYKQEEQRKLGIFENLNKHAFP 230

  Fly   174 VSINK-LYCFNYQPNKDDFPKNAGWDYFKLEAEFKHMLVPNEAWTLCSMNEKYELCDTYPRQIYV 237
            :|..: |:.|||   |:.||.| ||..:...:|:|...:|||:|.:..:|..||.|||||..|.|
  Rat   231 LSNGQALFAFNY---KEKFPVN-GWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAVIVV 291

  Fly   238 PKEATTLMLISSSRFRSKGRLPVLTYLH-NNKASICRCSQPLSG-FSARCLEDEQMLEAIRKTNS 300
            |.......|:..|.||:|||:|||:::| .::|:|.||.|||.| ...||.|||:.|:.|...|:
  Rat   292 PTSVKDDDLLKVSAFRAKGRVPVLSWIHPESQATITRCGQPLVGPNDKRCKEDEKYLQTIMDANA 356

  Fly   301 NTDYMYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLE----ACEQ 361
            .:..:.:.|.|....|..|:|.|.|||.|:.|.|.:..||.|.||||.|.||:|:.|    |.::
  Rat   357 QSHKLTIFDARQNSVADTNKAKGGGYECESAYPNAELIFLEIPNIHVMRESLRKLKEVVYPAIDE 421

  Fly   362 KSPTMSAFINALESSGWLKHIRSILDTSSFIANAVDKG-VSVVVHCSDGWDRTAQVCSLAQLMLN 425
                 |.:::.::.:.||::||.:|..:..||:.::.| .|||||||||||||.|:.|||.|||:
  Rat   422 -----SHWLSNVDGTHWLEYIRVLLAGAVRIADKIESGKTSVVVHCSDGWDRTPQLTSLAMLMLD 481

  Fly   426 PYYRTIKGFQALIEKDWLAFGHKFSERCGH---IQTDAREVSPIFTQFLDCTWQLMSQRSEAFEF 487
            .|||||.||:|||||:|::|||:|:.|.||   ...|| :.||||.||:||.||:..|...||||
  Rat   482 SYYRTIPGFEALIEKEWISFGHRFALRVGHGDDNHADA-DRSPIFLQFIDCVWQMTRQFPSAFEF 545

  Fly   488 NERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPNVDEAIK 552
            ||.||:.:.||::||.||||:.|||:.|:...:..:|.|||.|:.:.|:|:.||.:.......:.
  Rat   546 NELFLIAILDHLYSCLFGTFLCNCEQQRVREDVCAKTLSLWSYINSQLDEFSNPFFVSYDHHVLY 610

  Fly   553 ANLAPQCIKFWRGMYSRFESGIHPREPLGDVLLDSKEHCNSLEDHVQHLTKRIASFKNYISKSAK 617
            ...:...::.|...|.|:...:.|:.|:...|.:.......|...|:.| :|.|:.:...|.|.:
  Rat   611 PVASVSRLELWVNYYVRWNPRMRPQMPIHQNLKELLAVKAELRKRVEDL-QREAAARTVPSSSER 674

  Fly   618 KLQDATSAP 626
            ......|||
  Rat   675 GPSPTHSAP 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtmr6	NP_726322.1	PH-GRAM_MTMR6-like	78..173	CDD:270030	21/103 (20%)
		PTP-MTMR6-like	202..501	CDD:350380	141/308 (46%)
		FYVE_MTMR_unchar	693..753	CDD:277277
Mtmr1	XP_063133525.1	None