Protein Alignment Mtmr6 and mtmr7

DIOPT Version :10

• Sequence 1: NP_726322.1
• Gene: Mtmr6 / 37707
• FlyBaseID: FBgn0028497
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: XP_004911249.1
• Gene: mtmr7 / 100485851
• XenbaseID: XB-GENE-1008662
• Length: 657
• Species: Xenopus tropicalis
• Alignment Length: 682
• Identity: 320/682 - (46%)
• Similarity: 443/682 - (64%)
• Gaps: 57/682 - (8%)

  Fly    78 LKKVENVRMIDRYNTKNPTVGTLYLTATHLIFVE--PDSNKETWILHMHVASIEKLPLSTTGSPL 140
            |.||||||::||.:::...:||||||.||:||||  .::.||||||:..::||||...:|:|.|:
 Frog     6 LPKVENVRLLDRISSRKAALGTLYLTGTHIIFVENISETRKETWILYSQISSIEKQATATSGCPI 70

  Fly   141 LIRCKTFLSVTFVIPKDSECHDVYTSLLKLFQPVSINKLYCFNYQPNKDDFPKNAGWDYFKLEAE 205
            ||.||.|..:..:||::.:|||:|.||::|.:||...:||||:::||.|......||....|..|
 Frog    71 LIHCKNFQVIQLIIPQERDCHDIYLSLVRLSRPVKYEELYCFSFKPNLDKTEHEEGWKLVDLNEE 135

  Fly   206 FKHMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLT-YLHNNKA 269
            :..|.:|...|.:..:|..|.:||:||.::||||.||..:::.||:|||:||.|.|: |..:|.|
 Frog   136 YNRMGLPKSLWQMSDVNRDYRVCDSYPTELYVPKSATVPIIVGSSKFRSRGRFPTLSYYCQDNNA 200

  Fly   270 SICRCSQPLSGFSARCLEDEQMLEAIRKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYEN 334
            ||||.||||||||||||||||||:||||.|..:|::|||||||::|||||||||||||||..|.:
 Frog   201 SICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFLYVVDTRPKLNAMANRAAGKGYENEDNYSD 265

  Fly   335 IKFHFLGIENIHVQRASLQKVLEACEQKSPTMSAFINALESSGWLKHIRSILDTSSFIANAV-DK 398
            |||.|:|||||||.|.||||:||.||.:||:|..|:..||||||||||::|:|...|||.|| ::
 Frog   266 IKFQFIGIENIHVMRNSLQKMLEVCELRSPSMGDFLWGLESSGWLKHIKAIIDAGIFIAKAVSEE 330

  Fly   399 GVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHIQTDAREV 463
            |.||:|||||||||||||||:|.|:::|||||||||..||||||::|||||:.|.|::..|.:||
 Frog   331 GASVLVHCSDGWDRTAQVCSIASLLIDPYYRTIKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEV 395

  Fly   464 SPIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLW 528
            ||:..||::|.||||.|...|||||||||:.:|.||:|||:|.|:.||:|:|.::::.|||:|||
 Frog   396 SPVIDQFIECVWQLMEQFPCAFEFNERFLVHIHHHVYSCQYGNFLCNCQKERREIRVQERTYSLW 460

  Fly   529 GYMANHLNEYINPLYKPNVDE---AIKANLAPQCIKFWRGMYSRFESGIHPREPLGDVLLDSKEH 590
            .|:.....:|:||||:.:..:   .::.|.:|...|||||:|:|||.|:.||:.:.|.|...||.
 Frog   461 SYLWKQRLDYMNPLYRADHSQTQGTLRPNTSPSNFKFWRGLYNRFEKGMQPRQSVTDFLQAVKEE 525

  Fly   591 CNSLEDHVQHLTKRIASFKNYISKSAKKLQDATSAPGKVNKELSSNEINDNKYNYDKK---LSEL 652
            ...||:.::.:.||...|::.                .:|...|.|||:::    ||.   .:..
 Frog   526 TQQLEEELEFMQKRWQKFESQ----------------HLNGTKSFNEIHES----DKLQICATAY 570

  Fly   653 SAADDDHPLKASNMSFASLSLS-AEQSSPPQALPEEINS----VAVDWKPMRNVTTCSCSTPFDQ 712
            ::|:......::..||.|.|.| .|:.|......|.:.|    ::.:......|...||.:|..
 Frog   571 TSANSPQDYSSTLKSFPSRSPSQGEEDSALILTQEHLKSSDPDLSANSDQESGVEDLSCRSPSG- 634

  Fly   713 FSKKTHCWRCGDIFCERCIDKNVALPGHDSGK 744
                      ||           :||..||||
 Frog   635 ----------GD-----------SLPSEDSGK 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtmr6	NP_726322.1	PH-GRAM_MTMR6-like	78..173	CDD:270030	48/96 (50%)
		PTP-MTMR6-like	202..501	CDD:350380	188/300 (63%)
		FYVE_MTMR_unchar	693..753	CDD:277277	12/52 (23%)
mtmr7	XP_004911249.1	PH-GRAM_MTMR7	1..103	CDD:270152	48/96 (50%)
		PTP-MTMR7	132..433	CDD:350431	188/300 (63%)