Protein Alignment eIF2Bdelta and Eif2b2

DIOPT Version :10

• Sequence 1: NP_611790.1
• Gene: eIF2Bdelta / 37706
• FlyBaseID: FBgn0034858
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_114447.2
• Gene: Eif2b2 / 84005
• RGDID: 620820
• Length: 351
• Species: Rattus norvegicus
• Alignment Length: 308
• Identity: 79/308 - (25%)
• Similarity: 135/308 - (43%)
• Gaps: 60/308 - (19%)

  Fly   313 RLGVQYAKRTVVGSNARCIAFLHALRQVVHDFETPAKKEFGR---SLDAAVKHHVDHLHKCRPLA 374
            |:.......|.||:..|.:  |..:|:           |:||   ..|.:.:.  :.|||    .
  Rat    67 RMTAAQPSETTVGNMVRRV--LKIIRE-----------EYGRLHGRSDESDQQ--ESLHK----L 112

  Fly   375 VSVSNAYKQFKNQLTQLPADVPETESKELLVHFIDTYIENQIGKAAQAISGFLQEKITDGDVLLT 439
            ::.....:.|......|.:::.|. ..||||....| .||   .||||:     |.|...:|::|
  Rat   113 LTSGGLSEDFSFHYAPLKSNIIEA-INELLVELEGT-TEN---IAAQAL-----EHIHSNEVIMT 167

  Fly   440 FACSSLIQ-FICEEAKRRQVAFRVIVVDSRPGCEGQELLRRLHATGIPCTYVLINAVGYVMAEAT 503
            ...|..:: |:.|.|::|:  |.||..:..|.|:|.|:...|...||..|.:...|:..||:...
  Rat   168 IGFSRTVEAFLREAAQKRK--FHVIAAECAPFCQGHEMAVNLSEAGIETTVMTDAAIFAVMSRVN 230

  Fly   504 KVLLGAHALLANGYVMARTGTAQVALVANAHNVPVLVCCETHKFSERFQTDAIVYNELSDPNQLV 568
            ||::|...:||||.:.|..||..:||.|..|:.|::||....|.|.:|.::...:::...|.:::
  Rat   231 KVIIGTKTILANGSLRAVAGTHTLALAAKHHSTPLIVCAPMFKLSPQFPSEEDSFHKFVAPEEVL 295

  Fly   569 ---RGD-------KCQLSNWAAKGKLLPLNLSYDITPPELVSAVVTEV 606
               .||       .|.:               :|..||:|::..::.:
  Rat   296 PFTEGDILEKVSVHCPV---------------FDYVPPDLITLFISNI 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bdelta	NP_611790.1	IF-2B	323..611	CDD:395798	77/298 (26%)
Eif2b2	NP_114447.2	IF-2B	29..333	CDD:395798	79/308 (26%)