Protein Alignment eIF2Bdelta and Eif2b1

DIOPT Version :10

• Sequence 1: NP_611790.1
• Gene: eIF2Bdelta / 37706
• FlyBaseID: FBgn0034858
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_742026.1
• Gene: Eif2b1 / 64514
• RGDID: 620819
• Length: 305
• Species: Rattus norvegicus
• Alignment Length: 307
• Identity: 76/307 - (24%)
• Similarity: 147/307 - (47%)
• Gaps: 25/307 - (8%)

  Fly   316 VQYAKRTVVG--SNARCIAFLHALRQVVHDFETPAKKEFGRSLDAAVKHHVDHLHKCRPL--AVS 376
            ::|.|..:.|  :.|..:|.:..|.:.:       |::.|.::.....|....:.....:  :|:
  Rat     7 IKYFKSQMKGDPNMASAVAAIQTLLEFL-------KRDKGETIQGLRAHLTKAIETLCAVDSSVA 64

  Fly   377 VSNAYKQFKN--QLTQLP-ADVPETESKELLVHFIDTYIENQIGKAAQAISGFLQEKITDGDVLL 438
            ||:..:.|..  .||.|. :|.  ::.|::::...:.:: ::|..:...|:......|.||..:|
  Rat    65 VSSGGELFLRFISLTSLEYSDY--SKCKKIMIERGELFL-SRISLSRTKIASLCHAFIKDGARIL 126

  Fly   439 TFACSSLIQFICEEAKRRQVAFRVIVVDSRPGCEGQELLRRLHATGIPCTYVLINAVGYVMAEAT 503
            |.|.|.::..:.|||...:..|.|.:.:|:|...|:::.:.|....:|.|.||..||||:|.:..
  Rat   127 THAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKVD 191

  Fly   504 KVLLGAHALLANGYVMARTGTAQVALVANAHNVPVLVCCETHKFSERFQTDAIVYNELSDPNQL- 567
            .|::||..::.||.::.:.||.|:|:.|.|.|.|..|..|:.||...|.     .|:...|::.
  Rat   192 LVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFP-----LNQQDVPDKFK 251

  Fly   568 VRGDKCQLSNWAAKGKLLPLNLSYDITPPELVSAVVTEVAILPCTSV 614
            .:.|  .|.:..|...|...:...|.|.|.|::.:.|::.:|..::|
  Rat   252 YKAD--TLKSVQAGQDLKEEHPWVDYTSPSLITLLFTDLGVLTPSAV 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bdelta	NP_611790.1	IF-2B	323..611	CDD:395798	73/295 (25%)
Eif2b1	NP_742026.1	IF-2B	17..293	CDD:395798	72/292 (25%)