Protein Alignment eIF2Bdelta and eif2b2

DIOPT Version :10

• Sequence 1: NP_611790.1
• Gene: eIF2Bdelta / 37706
• FlyBaseID: FBgn0034858
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001164986.1
• Gene: eif2b2 / 496931
• XenbaseID: XB-GENE-974089
• Length: 351
• Species: Xenopus tropicalis
• Alignment Length: 299
• Identity: 78/299 - (26%)
• Similarity: 136/299 - (45%)
• Gaps: 42/299 - (14%)

  Fly   313 RLGVQYAKRTVVGSNARCIAFLHALRQVVHDFETPAKKEFGRSLDAAVKH-HVDHLHKCRPLAVS 376
            |:.......|.||:..|.:..|             .::|:||....:.:: ..:.||:    .::
 Frog    67 RMTAAQPSETTVGNMVRRVLKL-------------IREEYGRLRGCSEENDQQESLHR----LIT 114

  Fly   377 VSNAYKQFKNQLTQLPADVPETESKELLVHFIDTYIENQIGKAAQAISGFLQEKITDGDVLLTFA 441
            .......|...|..|.|:|.|..: |||:....| .:|   .|.||     :|.|...:|::|..
 Frog   115 AERLSDDFNTPLPLLKANVIEAVN-ELLIELEGT-TDN---IAIQA-----KEHIHSNEVIMTIG 169

  Fly   442 CSSLIQFICEEAKRRQVAFRVIVVDSRPGCEGQELLRRLHATGIPCTYVLINAVGYVMAEATKVL 506
            .|..:|...|||.|:: .|.|||.:..|.|:|.::...|...||..|.:...|:..||:...||:
 Frog   170 RSRTVQLFLEEAARKR-TFHVIVAECAPFCQGHDMAASLSKAGIETTVIPDAAIFAVMSRVNKVI 233

  Fly   507 LGAHALLANGYVMARTGTAQVALVANAHNVPVLVCCETHKFSERFQTDAIVYNELSDPNQLVRGD 571
            :|...:||||.:.|.:||..:||.|..|:.|::||....|.|.:|..:...:::...|.:::.
 Frog   234 IGTKTILANGSLRAVSGTHTLALAARHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVSPQEVLP-- 296

  Fly   572 KCQLSNWAAKGKLLPLNLSY----DITPPELVSAVVTEV 606
                   .::|::|....:|    |..||||::..::.:
 Frog   297 -------FSEGEILSQVSAYCPIFDHVPPELITLFISNI 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bdelta	NP_611790.1	IF-2B	323..611	CDD:395798	76/289 (26%)
eif2b2	NP_001164986.1	IF-2B	31..333	CDD:395798	78/299 (26%)