Protein Alignment eIF2Bdelta and Eif2b1

DIOPT Version :9

• Sequence 1: NP_611790.1
• Gene: eIF2Bdelta / 37706
• FlyBaseID: FBgn0034858
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_663346.1
• Gene: Eif2b1 / 209354
• MGIID: 2384802
• Length: 305
• Species: Mus musculus
• Alignment Length: 326
• Identity: 79/326 - (24%)
• Similarity: 135/326 - (41%)
• Gaps: 63/326 - (19%)

  Fly   316 VQYAKRTVVG--SNARCIAFLHALRQVVHDFETPAKKEFGRSLDAAVKHHVDHLHKCRPLAVSVS 378
            ::|.|..:.|  ..|..:|.:..|.:.:       |::.|.:|..              |..:::
Mouse     7 IEYFKSQMKGDPKMASAVAAIQTLLEFL-------KRDKGETLQG--------------LRANLT 50

  Fly   379 NAYKQFKNQLTQLPADVPETESKELLVHFID-TYIE-------------------NQIGKAAQAI 423
            .|.|    .|..:.:.|..:...||.:.||. |.:|                   .:|..:...|
Mouse    51 YAIK----TLCGVDSSVAVSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLRRISLSRNKI 111

  Fly   424 SGFLQEKITDGDVLLTFACSSLIQFICEEAKRRQVAFRVIVVDSRPGCEGQELLRRLHATGIPCT 488
            :......|.||..:||.|.|.::..:.|||...:..|.|.:.:|:|...|:::.:.|....:|.|
Mouse   112 ANLCHTFIKDGARILTHAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALSHLNVPVT 176

  Fly   489 YVLINAVGYVMAEATKVLLGAHALLANGYVMARTGTAQVALVANAHNVPVLVCCETHKFSERFQT 553
            .||..||||:|.:|..|::||..::.||.::.:.||.|:|:.|.|.|.|..|..|:.||...|..
Mouse   177 VVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPL 241

  Fly   554 DAIVYNELSDPNQLVRGDKCQLSNWAAKGKLLPLNLS-----YDITPPELVSAVVTEVAILPCTS 613
                       ||....||.:......|......:|.     .|.|.|.|::.:.|::.:|..::
Mouse   242 -----------NQEDVPDKFKYKADTLKSVQTGQDLKEEHPWVDYTSPSLITLLFTDLGVLTPSA 295

  Fly   614 V 614
            |
Mouse   296 V 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bdelta	NP_611790.1	GCD2	306..619	CDD:224105	79/326 (24%)
		IF-2B	323..611	CDD:279362	76/314 (24%)
Eif2b1	NP_663346.1	GCD2	5..305	CDD:224105	79/326 (24%)
		IF-2B	17..293	CDD:279362	75/311 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810