Protein Alignment eIF2Bdelta and eif-2Balpha

DIOPT Version :10

• Sequence 1: NP_611790.1
• Gene: eIF2Bdelta / 37706
• FlyBaseID: FBgn0034858
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_499106.1
• Gene: eif-2Balpha / 176348
• WormBaseID: WBGene00014221
• Length: 305
• Species: Caenorhabditis elegans
• Alignment Length: 304
• Identity: 73/304 - (24%)
• Similarity: 130/304 - (42%)
• Gaps: 52/304 - (17%)

  Fly   340 VVHDFETPAKKEFGRSLD-AAVKHHVDHLHKCRPLAVSVSNAYKQFKNQLTQLPADVPETE---- 399
            ::..|....:.:..:|.. |.|:..::.|.:.|...|:      :|:|:|.|:.|.:.:|:
 Worm     6 IISSFRGKLENDPSKSTSLATVETLLEVLDRSRATTVA------EFQNELNQVVAALEKTDYSST 64

  Fly   400 ----SKELLVHF-----------------IDTY-------IENQIGKAAQAISGFLQEKITDGDV 436
                :.:|...|                 :|.|       |:|..|..|: ||...:...|....
 Worm    65 SIRSAADLFTRFTSLAPAALLDQEDFSQVLDLYRQRARSFIKNVRGSRAK-ISKCARLFFTHHMN 128

  Fly   437 LLTFACSSLIQFICEEAKRRQVAFRVIVVDSRPGCEGQELLRRLHATGIPCTYVLINAVGYVMAE 501
            :||.:.|.::.....:|.:......|.|.:|:|...|:.:...|...|:|.|.||.:.|||||..
 Worm   129 ILTHSYSKVVLETILDAHKSGYHLHVWVTESQPDASGKLVFEELKKNGVPTTLVLDSCVGYVMER 193

  Fly   502 ATKVLLGAHALLANGYVMARTGTAQVALVANAHNVPVLVCCETHKFSERFQ-TDAIVYNELSDPN 565
            ...||:||..::..|.::.:.||..|.::|.:.:|||.||.||.||...|. ..|.:..|.....
 Worm   194 IQAVLVGAEGVMETGGIINKIGTVNVCIIAKSRHVPVYVCAETIKFVREFPLNQADIPQEFKYRT 258

  Fly   566 QLVRGDKCQLSNWAAKGKLLPLNLSYDITPPELVSAVVTEVAIL 609
            .::..:..:|.:        |   ..|.|.||.::.::|:|..:
 Worm   259 SVIERNNLELEH--------P---DVDYTAPEFLTLIITDVGAM 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bdelta	NP_611790.1	IF-2B	323..611	CDD:395798	73/304 (24%)
eif-2Balpha	NP_499106.1	IF-2B	15..293	CDD:395798	72/295 (24%)