Protein Alignment CG30414 and TMPRSS2

DIOPT Version :10

• Sequence 1: NP_611789.2
• Gene: CG30414 / 37705
• FlyBaseID: FBgn0050414
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_001128571.1
• Gene: TMPRSS2 / 7113
• HGNCID: 11876
• Length: 529
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 82/301 - (27%)
• Similarity: 121/301 - (40%)
• Gaps: 73/301 - (24%)

  Fly     8 LALLVCSIQLGEGAPGHLLDSSCGTTKPEFIPMITGGADAGLFSNPWMVK--VLGEKLCGGSLIT 70
            |..:.|.:.|.......                |.||..|...:.||.|.  |....:||||:||
Human   276 LRCIACGVNLNSSRQSR----------------IVGGESALPGAWPWQVSLHVQNVHVCGGSIIT 324

  Fly    71 SRFVLTAAHCIVST-----HMRVRLGEYKTRFPGKDCSRCVPKSYKLRRIRLGEYDTRFPGKDCC 130
            ..:::|||||:...     |.....|..:..|                         .|.|
Human   325 PEWIVTAAHCVEKPLNNPWHWTAFAGILRQSF-------------------------MFYG---- 360

  Fly   131 VPKSYELAVDRKILHADYNLNL-DNDIGLLRMKSFVQYSDYVRPICLLVEGHMAE-SPIFNITGW 193
              ..|:  |::.|.|.:|:... :|||.|::::..:.::|.|:|:||...|.|.: ..:..|:||
Human   361 --AGYQ--VEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGW 421

  Fly   194 GVTND-GTPSRRLQRATVYNTDLHFCRSKFT--KQVDESQICAA--GTNSDACHGDSGGPLSAQV 253
            |.|.: |..|..|..|.|...:...|.|::.  ..:..:.|||.  ..|.|:|.|||||||   |
Human   422 GATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPL---V 483

  Fly   254 PFAGS--WLTFQYGLVSYGSAACHSF--SVYTNVTHHRDWI 290
            ....:  ||   .|..|:||....::  .||.||....|||
Human   484 TSKNNIWWL---IGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30414	NP_611789.2	Tryp_SPc	41..290	CDD:238113	77/266 (29%)
TMPRSS2	NP_001128571.1	LDLa	150..185	CDD:238060
		SRCR_2	190..283	CDD:464747	2/6 (33%)
		Tryp_SPc	293..524	CDD:238113	79/268 (29%)