Protein Alignment CG30414 and TMPRSS3

DIOPT Version :10

• Sequence 1: NP_611789.2
• Gene: CG30414 / 37705
• FlyBaseID: FBgn0050414
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_076927.1
• Gene: TMPRSS3 / 64699
• HGNCID: 11877
• Length: 454
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 83/298 - (27%)
• Similarity: 130/298 - (43%)
• Gaps: 51/298 - (17%)

  Fly    14 SIQLGEG-APGHLLD---SSCGTTKPEFIPMITGGADAGLFSNPWM--VKVLGEKLCGGSLITSR 72
            |:.:.|| |.||::.   ::||..: .:...|.||..:.|...||.  ::..|..|||||:||..
Human   187 SVYVREGCASGHVVTLQCTACGHRR-GYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPL 250

  Fly    73 FVLTAAHCIVSTHMRVRLGEYKTRFPGKDCSRCVPKSYKLRRIRLGEYDTRFPGKDCCVPKSYEL 137
            :::|||||:...::                    |||:.::...:...|...|..
Human   251 WIITAAHCVYDLYL--------------------PKSWTIQVGLVSLLDNPAPSH---------- 285

  Fly   138 AVDRKILHADYN-LNLDNDIGLLRMKSFVQYSDYVRPICL-LVEGHMAESPIFNITGWGVTNDGT 200
            .|::.:.|:.|. ..|.|||.|:::...:.:::.::|:|| ..|.:..:..:...:|||.|.||.
Human   286 LVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGA 350

  Fly   201 --PSRRLQRATVYNTDLHFC--RSKFTKQVDESQICAAGTNS--DACHGDSGGPLSAQVPFAGSW 259
              .|..|..|.|.......|  |..:...:..|.:||.....  |:|.|||||||..|.  ...|
Human   351 GDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQE--RRLW 413

  Fly   260 LTFQYGLVSY--GSAACHSFSVYTNVTHHRDWIVNAIE 295
            ..  .|..|:  |.|..:...|||.||...|||...:|
Human   414 KL--VGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQME 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30414	NP_611789.2	Tryp_SPc	41..290	CDD:238113	72/260 (28%)
TMPRSS3	NP_076927.1	LDLa	74..107	CDD:238060
		SRCR_2	112..210	CDD:464747	8/22 (36%)
		Tryp_SPc	216..444	CDD:214473	72/261 (28%)