Protein Alignment CG30414 and PRSS2

DIOPT Version :10

• Sequence 1: NP_611789.2
• Gene: CG30414 / 37705
• FlyBaseID: FBgn0050414
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 74/272 - (27%)
• Similarity: 111/272 - (40%)
• Gaps: 56/272 - (20%)

  Fly    41 ITGGADAGLFSNPWMVKV-LGEKLCGGSLITSRFVLTAAHCIVSTHMRVRLGEYKTRFPGKDCSR 104
            |.||......|.|:.|.: .|...||||||:.::|::|.||..|.        ..::..|:.|
Human    24 IVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVSAGHCYKSA--------INSKLSGRGC-- 78

  Fly   105 CVPKSYKLRRIRLGEYDTRFPGKDCCVPKSYELAVD--RKILHADYN-LNLDNDIGLLRMKSFVQ 166
                .|...::||||::..       |.:..|..::  :.|.|..|| ..|||||.|:::.|...
Human    79 ----EYHRIQVRLGEHNIE-------VLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAV 132

  Fly   167 YSDYVRPICLLVEGHMAESPIFNITGWGVTNDGTPSRRLQRATVYNTDLHF----------CRSK 221
            .:..|..|.|......|.:... |:|||.|        |.....|..:|..          |.:.
Human   133 INSRVSAISLPTAPPAAGTESL-ISGWGNT--------LSSGADYPDELQCLDAPVLSQAECEAS 188

  Fly   222 FTKQVDESQICAA--GTNSDACHGDSGGPLSAQVPFAG--SWLTFQYGLVSYGSAACHSFSVYTN 282
            :..::..:..|..  ....|:|.||||||:.:.....|  ||        .||.|..:...|||.
Human   189 YPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSW--------GYGCAQKNRPGVYTK 245

  Fly   283 VTHHRDWIVNAI 294
            |.::.|||.:.|
Human   246 VYNYVDWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30414	NP_611789.2	Tryp_SPc	41..290	CDD:238113	71/266 (27%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	73/269 (27%)