Protein Alignment CG30414 and PRSS1

DIOPT Version :10

• Sequence 1: NP_611789.2
• Gene: CG30414 / 37705
• FlyBaseID: FBgn0050414
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 79/327 - (24%)
• Similarity: 120/327 - (36%)
• Gaps: 123/327 - (37%)

  Fly     1 MKFIAAGLALLVCSIQLGEGAPGHLLDSSCGTTKPEFIPMITGGADAGLFSNPWMVKV-LGEKLC 64
            :.|:||.||           ||   .|..         ..|.||.:....|.|:.|.: .|...|
Human     7 LTFVAAALA-----------AP---FDDD---------DKIVGGYNCEENSVPYQVSLNSGYHFC 48

  Fly    65 GGSLITSRFVLTAAHCIVSTHMRVRLGEYKTRFPGKDCSRCVPKSYKLRRIRLGEYDTRFPGKDC 129
            |||||..::|::|.||            ||:|.                ::||||::..
Human    49 GGSLINEQWVVSAGHC------------YKSRI----------------QVRLGEHNIE------ 79

  Fly   130 CVPKSYELAVD--RKILHADYN-LNLDNDIGLLRMKSFVQYSDYVRPI------------CLLVE 179
             |.:..|..::  :.|.|..|: ..|:|||.|:::.|....:..|..|            ||
Human    80 -VLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCL--- 140

  Fly   180 GHMAESPIFNITGWGVT-NDGTPSRRLQRATVYNTDLHF----------CRSKFTKQVDESQICA 233
                      |:|||.| :.|..         |..:|..          |.:.:..::..:..|.
Human   141 ----------ISGWGNTASSGAD---------YPDELQCLDAPVLSQAKCEASYPGKITSNMFCV 186

  Fly   234 A--GTNSDACHGDSGGPL--SAQVPFAGSWLTFQYGLVSYGS--AACHSFSVYTNVTHHRDWIVN 292
            .  ....|:|.||||||:  :.|:          .|:||:|.  |..:...|||.|.::..||.|
Human   187 GFLEGGKDSCQGDSGGPVVCNGQL----------QGVVSWGDGCAQKNKPGVYTKVYNYVKWIKN 241

  Fly   293 AI 294
            .|
Human   242 TI 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30414	NP_611789.2	Tryp_SPc	41..290	CDD:238113	67/281 (24%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	67/282 (24%)