DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30414 and hgfa

DIOPT Version :9

Sequence 1:	NP_001163264.1	Gene:	CG30414 / 37705	FlyBaseID:	FBgn0050414	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	XP_005164799.1	Gene:	hgfa / 493781	ZFINID:	ZDB-GENE-041014-2	Length:	712	Species:	Danio rerio

Alignment Length:	301	Identity:	72/301 - (23%)
Similarity:	106/301 - (35%)	Gaps:	90/301 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 GTTKPE-FI---PMITGG-----ADAGLFSNPWMVKVL--GEKLCGGSLITSRFVLTAAHCIVST 84
            |..||. ||   ..|.||     |:.|    .|:|.:.  ....||||||...:|||...|.
Zfish   463 GGPKPSCFIHKTTRIVGGMRVQRAEDG----SWVVSIQKGNRHWCGGSLIREEWVLTDQQCF--- 520

  Fly    85 HMRVRLGEYKTRFPGKDCSRCVPKSYKLRRIRLGEYDTRFPGKDCCVPKSYELAVDRKILHADYN 149
                              |.|||.        |.||                 .|...:||.:.:
Zfish   521 ------------------STCVPD--------LSEY-----------------TVQVGLLHLNAS 542

  Fly   150 LNLD-------------NDIGLLRMKSFVQYSDYVRPICLLVEG-HMAESPIFNITGWGVTNDGT 200
            ....             :::.||::.:....|::||.:.|.|.| .:||..:..:.|||.|. ||
Zfish   543 AGTQALRIAHVVCGPEGSNLALLKLTTPAPLSEHVRTVQLPVAGCAVAEGTLCLMYGWGDTK-GT 606

  Fly   201 PSRRLQRATVYNTDLHFCRSKFTKQ-------VDESQICAAG-TNSDACHGDSGGPLSAQVPFAG 257
            .    ...::....|....:|...|       :.|::|||.| .:...|..|.||||..|.  ..
Zfish   607 G----HEGSLKMVGLPIVSNKRCSQSHNGILPITETKICAGGKRDQGVCEKDYGGPLVCQE--GE 665

  Fly   258 SWLTFQYGLVSYGSAACHSFSVYTNVTHHRDWIVNAIEDFS 298
            |.:.....:...|.|.....:|:.||..:.:||....:.:|
Zfish   666 SKVIVGVSINGRGCAVARRPAVFVNVAFYSEWIRKVFKYYS 706

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30414	NP_001163264.1	Tryp_SPc	41..290	CDD:214473	64/277 (23%)
CG30414	NP_001163264.1	Tryp_SPc	41..290	CDD:238113	64/277 (23%)
hgfa	XP_005164799.1	PAN_AP_HGF	<50..107	CDD:238532
		KR	111..192	CDD:238056
		KR	195..275	CDD:214527
		KR	287..367	CDD:214527
		KR	374..451	CDD:214527
		Tryp_SPc	476..698	CDD:214473	64/278 (23%)
		Tryp_SPc	477..701	CDD:238113	66/280 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575861
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930