Protein Alignment CG30414 and TMPRSS11A

DIOPT Version :10

• Sequence 1: NP_611789.2
• Gene: CG30414 / 37705
• FlyBaseID: FBgn0050414
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_872412.3
• Gene: TMPRSS11A / 339967
• HGNCID: 27954
• Length: 421
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 80/303 - (26%)
• Similarity: 131/303 - (43%)
• Gaps: 56/303 - (18%)

  Fly     8 LALLVCSIQLG--EGAPGHL-LDSSCG-TTKPEFIPMITGGADAGLFSNPWMVKVLGEKL--CGG 66
            |.:...|:|:.  ..:.|.| :.:||| ...|..:..|..|..|...:.||...:..:.:  ||.
Human   153 LPINASSVQVNAMSSSTGELTVQASCGKRVVPLNVNRIASGVIAPKAAWPWQASLQYDNIHQCGA 217

  Fly    67 SLITSRFVLTAAHCIVSTHMRVRLGEYKTRFPGKDCSRCVPKSYKLRRIRLGEYDTRFPGKDCCV 131
            :||::.:::|||||         ..:||.           |..:.:      .:.|:..
Human   218 TLISNTWLVTAAHC---------FQKYKN-----------PHQWTV------SFGTKIN------ 250

  Fly   132 PKSYELAVDRKILHADY-NLNLDNDIGLLRMKSFVQYSDYVRPICLLVEGHMAESP--IFNITGW 193
            |...:..|.|.|:|..| :...:.||.::::.|.|.:||.:|.|| |.|...:..|  ..:|||:
Human   251 PPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQIC-LPEASASFQPNLTVHITGF 314

  Fly   194 GVTNDGTPSR---RLQRATVYNTDLHFCRSK--FTKQVDESQICAAGTNS--DACHGDSGGPLSA 251
            |....|..|:   |..|..:.:.|:  |:..  :...:.....||.....  |||.|||||||..
Human   315 GALYYGGESQNDLREARVKIISDDV--CKQPQVYGNDIKPGMFCAGYMEGIYDACRGDSGGPLVT 377

  Fly   252 QVPFAGSWLTFQYGLVSYGSAACHSF--SVYTNVTHHRDWIVN 292
            : ....:|  :..|:||:|.......  .|||.||::|:||.:
Human   378 R-DLKDTW--YLIGIVSWGDNCGQKDKPGVYTQVTYYRNWIAS 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30414	NP_611789.2	Tryp_SPc	41..290	CDD:238113	69/262 (26%)
TMPRSS11A	NP_872412.3	SEA	49..149	CDD:460188
		Tryp_SPc	190..418	CDD:238113	71/266 (27%)