DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30414 and Habp2

DIOPT Version :9

Sequence 1:	NP_001163264.1	Gene:	CG30414 / 37705	FlyBaseID:	FBgn0050414	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_001316864.1	Gene:	Habp2 / 226243	MGIID:	1196378	Length:	554	Species:	Mus musculus

Alignment Length:	297	Identity:	88/297 - (29%)
Similarity:	131/297 - (44%)	Gaps:	70/297 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 PGHLLDSSCGTTK--PEFIPMITGGADAGLFSNPWMVKVLGE----------KLCGGSLITSRFV 74
            ||.   .|||.|:  ...:..|.||..:....:||.|.:...          ..|||:||...:|
Mouse   290 PGF---ESCGKTEVAEHAVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGALIHPCWV 351

  Fly    75 LTAAHC--IVSTHMRVRLGEYKTRFPGKDCSRCVPKSYKLRRIRLGEYDTRFPGKDCCVPKSYE- 136
            ||||||  |.:.|::|.||:                                  :|....:|:|
Mouse   352 LTAAHCTDINTKHLKVVLGD----------------------------------QDLKKTESHEQ 382

  Fly   137 -LAVDRKILHADYNLNLD---NDIGLLRMKSFVQY----SDYVRPICLLVEGHMAESPIFNITGW 193
             ..|::.:.::.||...:   |||.||::|....:    |.||:.:||..:...:.:.. :|:||
Mouse   383 TFRVEKILKYSQYNERDEIPHNDIALLKLKPVGGHCALESRYVKTVCLPSDPFPSGTEC-HISGW 446

  Fly   194 GVTNDGTPSRRLQRATVYNTDLHFCRSK--FTKQVDESQICAAG---TNSDACHGDSGGPLSAQV 253
            |||..|..||:|..|.|.......|.|:  :...:|:|.|||..   ..||.|.|||||||:.:.
Mouse   447 GVTETGEGSRQLLDAKVKLIANPLCNSRQLYDHTIDDSMICAGNLQKPGSDTCQGDSGGPLTCEK 511

  Fly   254 PFAGSWLTFQYGLVSYGSAACHSFSVYTNVTHHRDWI 290
            .  |::  :.||:||:|........|||.||...:||
Mouse   512 D--GTY--YVYGIVSWGQECGKKPGVYTQVTKFLNWI 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30414	NP_001163264.1	Tryp_SPc	41..290	CDD:214473	80/274 (29%)
CG30414	NP_001163264.1	Tryp_SPc	41..290	CDD:238113	80/274 (29%)
Habp2	NP_001316864.1	EGF_CA	67..103	CDD:238011
		EGF_CA	150..182	CDD:238011
		KR	187..271	CDD:238056
		Tryp_SPc	308..547	CDD:238113	82/276 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833194
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840