DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30414 and Mst1

DIOPT Version :9

Sequence 1:	NP_001163264.1	Gene:	CG30414 / 37705	FlyBaseID:	FBgn0050414	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_032269.3	Gene:	Mst1 / 15235	MGIID:	96080	Length:	716	Species:	Mus musculus

Alignment Length:	309	Identity:	77/309 - (24%)
Similarity:	114/309 - (36%)	Gaps:	82/309 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CSIQ-LGEGAPGHLLD-------SSCGTTKPEFIPMITGGADAGLFSNPWMVKV---LGEKLCGG 66
            |::| ..:..|..:||       ..||....:...:...|...|  ::||.|.:   .|:..|||
Mouse   452 CALQRCDDDQPPSILDPPDQVVFEKCGKRVDKSNKLRVVGGHPG--NSPWTVSLRNRQGQHFCGG 514

  Fly    67 SLITSRFVLTAAHCIVSTH-----MRVRLGEYKTRFPGKDCSRCVPKSYKLRRIRLGEYDTRFPG 126
            ||:..::||||..||.|.|     ..|.||...        ....|....|:|:.:        .
Mouse   515 SLVKEQWVLTARQCIWSCHEPLTGYEVWLGTIN--------QNPQPGEANLQRVPV--------A 563

  Fly   127 KDCCVPKSYELAVDRKILHADYNLNLDNDIGLLRMKSFVQYSDYVRPICLLVEGHMA-ESPIFNI 190
            |..|.|...:|.                   ||:::..|..:.:|..|||..|.::. ......|
Mouse   564 KAVCGPAGSQLV-------------------LLKLERPVILNHHVALICLPPEQYVVPPGTKCEI 609

  Fly   191 TGWGVTNDGTPSRRLQRATVYNTDLHF----------CRSKFTKQVDESQICAAG--TNSDACHG 243
            .||| .:.||.:         ||.||.          |.:|:...:.||:||..|  ....||.|
Mouse   610 AGWG-ESIGTSN---------NTVLHVASMNVISNQECNTKYRGHIQESEICTQGLVVPVGACEG 664

  Fly   244 DSGGPLSAQVPFAGSWLTFQYGLVSYGSAACHSF--SVYTNVTHHRDWI 290
            |.||||:...  ...|:.  .||:..........  :::|.|:...|||
Mouse   665 DYGGPLACYT--HDCWVL--QGLIIPNRVCARPRWPAIFTRVSVFVDWI 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30414	NP_001163264.1	Tryp_SPc	41..290	CDD:214473	68/271 (25%)
CG30414	NP_001163264.1	Tryp_SPc	41..290	CDD:238113	68/271 (25%)
Mst1	NP_032269.3	PAN_1	25..96	CDD:278453
		KR	108..188	CDD:214527
		KR	191..269	CDD:214527
		KR	291..372	CDD:214527
		KR	377..459	CDD:214527	2/6 (33%)
		Tryp_SPc	488..709	CDD:214473	68/271 (25%)
		Tryp_SPc	489..712	CDD:238113	70/272 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833174
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930