DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30414 and Hgf

DIOPT Version :9

Sequence 1:	NP_001163264.1	Gene:	CG30414 / 37705	FlyBaseID:	FBgn0050414	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_001276387.1	Gene:	Hgf / 15234	MGIID:	96079	Length:	728	Species:	Mus musculus

Alignment Length:	302	Identity:	75/302 - (24%)
Similarity:	108/302 - (35%)	Gaps:	101/302 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SCGTTKP----EFIPMITGGADAGLFSNPWMV--KVLGEKLCGGSLITSRFVLTAAHCIVSTHMR 87
            ||..||.    ..||..|        :..|||  |...:.:||||||...:||||..|
Mouse   487 SCAKTKQLRVVNGIPTQT--------TVGWMVSLKYRNKHICGGSLIKESWVLTARQC------- 536

  Fly    88 VRLGEYKTRFPGKDCSRCVPKSYKLRRIRLGEYDTRFPGKDCCVPKSYELAVDRKILHADYNLNL 152
                     ||.::      |..|.....||.:|....|::           .||.:     ||:
Mouse   537 ---------FPARN------KDLKDYEAWLGIHDVHERGEE-----------KRKQI-----LNI 570

  Fly   153 D--------NDIGLLRMKSFVQYSDYVRPICLLVEG-HMAESPIFNITGWGVTN----DGTPSRR 204
            .        :|:.||::.......::|..|.|...| .:.|....:|.|||.|.    ||.
Mouse   571 SQLVYGPEGSDLVLLKLARPAILDNFVSTIDLPSYGCTIPEKTTCSIYGWGYTGLINADGL---- 631

  Fly   205 LQRATVYNTDLHFC----RSKFTKQVDESQICAAG--TNSDACHGDSGGPLSAQ----------- 252
            |:.|.:|......|    :.|.|  ::||::||..  ..|..|.||.||||..:
Mouse   632 LRVAHLYIMGNEKCSQHHQGKVT--LNESELCAGAEKIGSGPCEGDYGGPLICEQHKMRMVLGVI 694

  Fly   253 VPFAGSWLTFQYGLVSYGSAACHSFSVYTNVTHHRDWIVNAI 294
            ||..|..:..:.|             ::..|.::..||...|
Mouse   695 VPGRGCAIPNRPG-------------IFVRVAYYAKWIHKVI 723

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30414	NP_001163264.1	Tryp_SPc	41..290	CDD:214473	66/280 (24%)
CG30414	NP_001163264.1	Tryp_SPc	41..290	CDD:238113	66/280 (24%)
Hgf	NP_001276387.1	PAN_APPLE	41..123	CDD:238074
		KR	127..209	CDD:214527
		KR	211..289	CDD:214527
		KR	305..385	CDD:214527
		KR	389..471	CDD:238056
		Tryp_SPc	495..719	CDD:214473	68/288 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833152
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930