Protein Alignment Golgin245 and CIP1

DIOPT Version :9

• Sequence 1: NP_611787.2
• Gene: Golgin245 / 37702
• FlyBaseID: FBgn0034854
• Length: 1489
• Species: Drosophila melanogaster
• Sequence 2: NP_001330520.1
• Gene: CIP1 / 834184
• AraportID: AT5G41790
• Length: 1586
• Species: Arabidopsis thaliana
• Alignment Length: 1569
• Identity: 342/1569 - (21%)
• Similarity: 689/1569 - (43%)
• Gaps: 376/1569 - (23%)

  Fly   160 HKYRCRYTDLAKKYKELERDSSKARSVLVETQDKALRRISELREQCTLEQQAKAHLEEALRVEMD 224
            ||:|    :..|.:.|...|..|. .:|..|:.:...:::::   ..:.:....:.:|:.|..:.
plant     4 HKFR----ETLKSFFEPHFDHEKG-EMLKGTKTEIDEKVNKI---LGMVESGDVNEDESNRQVVA 60

  Fly   225 DMSCKMQAYQTKLQLLGENPENITAALERSGQQLESEQLIDLEESIGKSPLSTNGSSGVSDLQRL 289
            |:   ::.:.::.|.|....:::|.               ::.:.:.....|::.||..||....
plant    61 DL---VKEFYSEYQSLYRQYDDLTG---------------EIRKKVNGKGESSSSSSSDSDSDHS 107

  Fly   290 LKERDEQLKSVTEKYEAVRKQEEENVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQRESHN 354
            .|.:        .|.....|.|::..|:....||    ::|..:.|:..|:.||.....::|:.:
plant   108 SKRK--------VKRNGNGKVEKDVELVTGALKQ----QIEAANLEIADLKGKLTTTVEEKEAVD 160

  Fly   355 NEVKEQFKKLQATKQEVDAKL-MATEHLLNTLKESYAIKEQQVVTLEAQLE-AIRVENE--QKVK 415
            :|::....||:.: :|:.:|| :.||.|.:  ::|.|:.:.:  .|..:|| |.:.|.:  ||::
plant   161 SELELALMKLKES-EEISSKLKLETEKLED--EKSIALSDNR--ELHQKLEVAGKTETDLNQKLE 220

  Fly   416 DLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLE---SLRSEQAAKEQQLKHLKEQL 477
            |::|:.::..|:..:.   :|:.|.|.:.||....:.|||.:   :|:.:..|.||::..|...:
plant   221 DIKKERDELQTERDNG---IKRFQEAEKVAEDWKTTSDQLKDETSNLKQQLEASEQRVSELTSGM 282

  Fly   478 GKLKQENENY------------------------LDKLRENKKSSDSQ-----------TNEAQD 507
            ...::||::.                        |.:::|..|..:|:           ..|:..
plant   283 NSAEEENKSLSLKVSEISDVIQQGQTTIQELISELGEMKEKYKEKESEHSSLVELHKTHERESSS 347

  Fly   508 QQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKE--------------- 557
            |.|:|:|..:.:| ||:|  :...||.|   |:||| .||..|:..||.|
plant   348 QVKELEAHIESSE-KLVA--DFTQSLNN---AEEEK-KLLSQKIAELSNEIQEAQNTMQELMSES 405

  Fly   558 ------NDVNVEKLHHINEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEE 616
                  :.|...:|..:.:..|....||..:.:||       ||:|.|::..::.|.|:|.|.||
plant   406 GQLKESHSVKERELFSLRDIHEIHQRDSSTRASEL-------EAQLESSKQQVSDLSASLKAAEE 463

  Fly   617 QAASLE----QSLNALKTESEHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQSQRE 677
            :..::.    :::|.|: ::::::|:|..   :|.::...|::.  |::|:...|.....|....
plant   464 ENKAISSKNVETMNKLE-QTQNTIQELMA---ELGKLKDSHREK--ESELSSLVEVHETHQRDSS 522

  Fly   678 LHALELEKSLEMERESVAALNSEKASQEEQHRL---KLEQLQREIQILQ---------------- 723
            :|..|||:.:|..::.||.||....:.||:.::   |:.:|..||:..|
plant   523 IHVKELEEQVESSKKLVAELNQTLNNAEEEKKVLSQKIAELSNEIKEAQNTIQELVSESGQLKES 587

  Fly   724 ---------------DQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNK----- 768
                           :.|....|..|:.|:.|||:..|.::.....|...|:|.||..:|
plant   588 HSVKDRDLFSLRDIHETHQRESSTRVSELEAQLESSEQRISDLTVDLKDAEEENKAISSKNLEIM 652

  Fly   769 -------------LNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVTG 820
                         ::::.:..::|:.|.|:.|:.:::...::||........|.||:.|..|:..
plant   653 DKLEQAQNTIKELMDELGELKDRHKEKESELSSLVKSADQQVADMKQSLDNAEEEKKMLSQRILD 717

  Fly   821 ILEEI----GTMQAQM---QQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQ 878
            |..||    .|:|..|   :|:::||...|||...|....|:.|:|          :|.:|.|::
plant   718 ISNEIQEAQKTIQEHMSESEQLKESHGVKERELTGLRDIHETHQRE----------SSTRLSELE 772

  Fly   879 SENTKLAERNCL--------LEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQNAQELMDH 935
            :: .||.|:..:        .||:...|.|.:....||:.:.|:|:|:::.|.::.::.....::
plant   773 TQ-LKLLEQRVVDLSASLNAAEEEKKSLSSMILEITDELKQAQSKVQELVTELAESKDTLTQKEN 836

  Fly   936 DHRTLQDKCDAYEKDKLLTKHTLDC-LQSASEELHRVKANL---DRELKEQDQQLSELRERQREQ 996
            :..:..:..:|:::|.......|:. ::||.|::..:..||   :.|.|...||:||:..:.:..
plant   837 ELSSFVEVHEAHKRDSSSQVKELEARVESAEEQVKELNQNLNSSEEEKKILSQQISEMSIKIKRA 901

  Fly   997 EQQLKDQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQATNSSYTTQIATLE 1061
            |..:::.:....:||..::|.:.:|    .:||:..:.:::              ..:||:..||
plant   902 ESTIQELSSESERLKGSHAEKDNEL----FSLRDIHETHQR--------------ELSTQLRGLE 948

  Fly  1062 ARWSAANSDVERLHEANDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVELQEAMATRDRQLQE 1126
            |:..::...|..|.|:..|.:.|...:..|..:..:|::       |..:.:||..|...:..::
plant   949 AQLESSEHRVLELSESLKAAEEESRTMSTKISETSDELE-------RTQIMVQELTADSSKLKEQ 1006

  Fly  1127 KIEASEKLAKFDEILIENEYLNK-HTKQLEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMA 1190
            ..|...||.    :|.|.:..:: ..|:|||.:   |.|:.:|:|::..:..|:.:.......:.
plant  1007 LAEKESKLF----LLTEKDSKSQVQIKELEATV---ATLELELESVRARIIDLETEIASKTTVVE 1064

  Fly  1191 EKETQSATATAEVSELKKAIEEQAVELT--------RQKEHASFV---TEQSDAVQKDL--LQAQ 1242
            :.|.|:....|.:|||:|.:||:..||:        ..|:.:|.:   |.:.|.::.:|  :..|
plant  1065 QLEAQNREMVARISELEKTMEERGTELSALTQKLEDNDKQSSSSIETLTAEIDGLRAELDSMSVQ 1129

  Fly  1243 QQLHDKQIELAMSRDEQA-----LLQAEADGLRQEVICLKEHLSPSTDSDSLRS-LNERLQRELE 1301
            ::..:||:   :.:.|:|     .|..|.:||||:|..|          ||.|: |..:|:::.|
plant  1130 KEEVEKQM---VCKSEEASVKIKRLDDEVNGLRQQVASL----------DSQRAELEIQLEKKSE 1181

  Fly  1302 DLKHKSAGAESNMQQEI-----------EELQANNQQMAERINELETLRAGIQAQQL---LASMA 1352
            ::. :.....:|:::||           ||:...::::..|..|||||  |.|..:|   |.:..
plant  1182 EIS-EYLSQITNLKEEIINKVKVHESILEEINGLSEKIKGRELELETL--GKQRSELDEELRTKK 1243

  Fly  1353 PKNVQ----------EAAAAGE---------------KAELESKLK-------EIMNEVQDVTNR 1385
            .:|||          |..|..|               |:|.|::|:       |:.|::.||  :
plant  1244 EENVQMHDKINVASSEIMALTELINNLKNELDSLQVQKSETEAELEREKQEKSELSNQITDV--Q 1306

  Fly  1386 NLFLEQKCENFLILEQSNERLKLQNAKLSRQLDETL--VSMQHSEA-----------------VP 1431
            ...:||:.. :..||:.::::.    :|.::.:.||  |::.:.||                 :.
plant  1307 KALVEQEAA-YNTLEEEHKQIN----ELFKETEATLNKVTVDYKEAQRLLEERGKEVTSRDSTIG 1366

  Fly  1432 ANTE-FEYLRNIMFQYLTGNTNNETLVKVISAV---LKFSPQQ----AQVALEKEH--------- 1479
            .:.| .|.|||.:  .:.|: ..|||::.||.:   |:.|.|:    .||..|||.
plant  1367 VHEETMESLRNEL--EMKGD-EIETLMEKISNIEVKLRLSNQKLRVTEQVLTEKEEAFRKEEAKH 1428

  Fly  1480 -QRRSLLNK 1487
             :.::||.|
plant  1429 LEEQALLEK 1437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Golgin245	NP_611787.2	Smc	286..1089	CDD:224117	206/940 (22%)
		Phage_GPO	<306..421	CDD:301727	31/118 (26%)
		Smc	737..1442	CDD:224117	183/827 (22%)
		MIT_CorA-like	<1244..>1333	CDD:294313	24/105 (23%)
		Grip	1433..1477	CDD:197860	16/51 (31%)
CIP1	NP_001330520.1	KIP1	14..78	CDD:311624	10/70 (14%)
		SMC_N	134..913	CDD:330553	183/817 (22%)
		SMC_N	656..1434	CDD:330553	187/846 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100282
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900