Protein Alignment Golgin245 and alm1

DIOPT Version :9

• Sequence 1: NP_611787.2
• Gene: Golgin245 / 37702
• FlyBaseID: FBgn0034854
• Length: 1489
• Species: Drosophila melanogaster
• Sequence 2: NP_594092.1
• Gene: alm1 / 2542883
• PomBaseID: SPAC1486.04c
• Length: 1727
• Species: Schizosaccharomyces pombe
• Alignment Length: 1729
• Identity: 380/1729 - (21%)
• Similarity: 714/1729 - (41%)
• Gaps: 427/1729 - (24%)

  Fly     6 KNKLIEEVKASPSKFQQFANAAQAA---VSSSSSTTPNSETNTSN-NENFFSITEEDTP---QNS 63
            :|.|.:::.....:.|...|.|:.:   :|...:...:.:||..| |:.|.::|.|:..   .||
pombe    65 ENVLTKKINFLEQQLQSSNNQAEESRNLISVLRNENESLKTNLENQNKRFDALTTENQSLRRANS 129

  Fly    64 PYRIQKLPATSASALRGRSTQSLNGATSRTRKLSNSSMASDVSFRLPTYEAPAVYHLQSDLDETS 128
            ..:.|...|:...::.....::|..        .||.:...|.         :.:...||::|..
pombe   130 ELQEQSKIASEQLSIAKDQIEALQN--------ENSHLGEQVQ---------SAHQALSDIEERK 177

  Fly   129 SEFDDSASTARLDVITKDQLYDAYKKSLDRYHKYRCRYTDLAKKYKELERDSSKARSVL------ 187
            .:...::|::|:    |:::....|.:|         .:|||    .|:.|.||....|
pombe   178 KQHMFASSSSRV----KEEILVQEKSAL---------VSDLA----SLQSDHSKVCEKLEVSSRQ 225

  Fly   188 VETQDKAL----RRISELREQCTLEQQAKAHLEE----ALRVEMDDMSCKMQAYQTKLQLLGENP 244
            |:..:|.|    ::.:||.|:..|.:|.:::...    :..:|.|..|.|      :|:...|..
pombe   226 VQDLEKKLAGLAQQNTELNEKIQLFEQKRSNYSSDGNISKILETDPTSIK------ELEEEVETQ 284

  Fly   245 ENITAALERSGQQLESEQLIDLEESIGKSPLSTNGSSGVSDLQRLLKERDEQLKSVTEKYEAVRK 309
            :.:||..|....:|:||.....|:...:..|..|.:..:::.::.|...:..|:.:.|||::|..
pombe   285 KRLTALWESKSSELQSEVAALQEKLTSQQSLYNNVTEELNNNKQQLLISENSLRELQEKYDSVVS 349

  Fly   310 Q-----EEENVLL---------LAQTKQAIHTELELKDTEV----RKLQEKLKQLESQRESHNNE 356
            :     |.:|..:         |||...|:... |...|:|    .|||:|:..|:.|.:...|:
pombe   350 ELQVVKENKNTSVSAGVGLFSPLAQKLSAVQNP-EFSFTKVYSDNMKLQQKVSSLKLQLDRLTNK 413

  Fly   357 VK---EQFK-KLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRVENE------ 411
            ..   ||.| ::...||: .::::.....:|.|.||.......:..::|:|.:.::..|
pombe   414 FSSFCEQVKQRIPVVKQQ-RSEIVRNNIYMNFLSESLETSNNNLTKVQAELLSTKMRQEACYLQL 477

  Fly   412 ----QKVKDLQKQ-----------NE--DRNTQA-------------SDSSEQL--KKLQ--AAV 442
                .:..||.::           ||  .||..|             |.:||.|  |:|.  :::
pombe   478 TASRTQCSDLSREVICLMAELDHLNETKSRNVPATVQVALDEYAQNPSTASETLVNKELANFSSI 542

  Fly   443 QDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQD 507
            ::|.|:.|   :|.|.:|:.:...|.|.:.::.|:....:||.|   .|.|..|:.:|:.|.::.
pombe   543 KEAVSKTL---ELREKVRALECDVEIQKQTVQYQISNAVKENSN---TLSEQIKNLESELNSSKI 601

  Fly   508 QQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHI--NE 570
            :.:.|.     .|..||  :|:|.:.|:...:.......::||:|::. |:...:||.:.:  ||
pombe   602 KNESLL-----NERNLL--KEMLATSRSSILSHNSSAGNIDDKMKSID-ESTRELEKNYEVYRNE 658

  Fly   571 Q---REAQSTDSQQKINELRAAKDEAE----AKLLSTEHSLNALQAALSAKEEQAASLEQSLNAL 628
            .   :|:.|..:|..::|:.|.:.|.|    .:.|||:...||               ...:.|.
pombe   659 MTAIQESLSKRNQDLLSEMEAIRKELENSKYQQQLSTDRLTNA---------------NNDVEAF 708

  Fly   629 KTESEHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQS-----QRELHALELEKSLE 688
            |.|:    ::||..|..|.:|:.|..|     :.::..|||..:.|     :.||:|.:.||.|.
pombe   709 KKEA----KELRSINQNLQDIISRQDQ-----RASKFAEELLHVNSLAERLKGELNASKGEKDLR 764

  Fly   689 MERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHANSESETVAALKGQLEALSQDLATSQA 753
            ...:......::|...|   |.:|..|..::|...:|...|:    ||.|.:.|:..:.|:.|..
pombe   765 KRTQERLISENDKLLAE---RERLMSLVSDLQTFLNQQQLSD----AARKVKFESEKESLSLSLQ 822

  Fly   754 SLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQAR- 817
            .|  ||...|.| |.|:.::|..|:   ...:.|:|::.|..|.......:|::...::.::.:
pombe   823 KL--KESNEKMS-NDLHSLQKSLEK---SGIEYSSRIKTLMLEKQSLSEDNRKLLDNQQMMEIKL 881

  Fly   818 --VTGILE----EIGTMQAQM-QQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLE 875
              :.|::|    ...|::|:. ||...|:||.|   ..|||.:..||.:.....:|...:...:|
pombe   882 QELNGVIELEKQRFSTLEAKFTQQKNTSYSERE---ALLESSLSDLQSKHTSLESQYNYSLRNIE 943

  Fly   876 EIQSENTKLAERNCLLEE----------------QTNH-----LESQLQAKQDEIGKIQAKLQQV 919
            ::|:. :||||.  ::|.                :.||     ||.::...||||.....:.:.:
pombe   944 QLQAA-SKLAEE--MVERVKTEYDEYRLQTSESLEKNHLKITSLEQRIVILQDEIASSSLRCENI 1005

  Fly   920 -----------LDEHSKLQNAQELMDHDHRTLQ--DKCDAYEKDKLLTKHTLDCLQSASEELHRV 971
                       |:|:..|.|  ||..|.:...|  :|.:.|::..||          .:|:|.:.
pombe  1006 TKDSETRVALLLEENKHLNN--ELSSHRNAEKQHLEKENDYKQQLLL----------VTEDLRKT 1058

  Fly   972 KANLDRE-LKEQDQQ--LSELRERQREQEQQLKDQAERCAKLKAQNSESET-QLQATISNLREQL 1032
            :.:.::| |:..|.:  |.:|||...:..:|::|..:..| |||..:||:. .:......||:::
pombe  1059 REDYEKELLRHADARSTLQKLREDYTKALEQVEDLNKEIA-LKAGINESQPFPISEKEDPLRQEV 1122

  Fly  1033 DAYKQTEQGIQEKLQATNSSY---TTQIATLEARWSAANSD----VERLHEANDALQLEMEQLKI 1090
            ...|:....:..:||::|.::   |:....|::......||    |:|:.:..:.:..:.:.|.:
pombe  1123 YVLKKQNAMLLTQLQSSNLNFAEITSPSPDLDSVMKLGLSDLQNHVKRISKEMEIISCQRQLLFL 1187

  Fly  1091 KHGQEREEVKESIAQKNRQVVELQEAMATRDRQLQEKIEASEKLAKFDEILIENEYLNKHTKQLE 1155
                |.:::|.::...||.:.:||..:..:|..     ..||.:.:....|.....||:..|.|.
pombe  1188 ----ENKKLKRTVESSNRVIADLQRGITEKDVS-----STSESVGERSNYLNMVALLNESNKSLR 1243

  Fly  1156 AELAES----AELKEKLKSLQCELYVLQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVE 1216
            ..|..:    .||:||:::|:.:|...:...||       .|:|..|..|.|.:|:.:.||
pombe  1244 ENLERNEEVITELREKIETLKTDLANFRLNKEQ-------LESQLQTEKAAVKKLENSNEE---- 1297

  Fly  1217 LTRQKEHASFVTEQSDAVQKDLLQAQQQLHDKQIELAMSRDEQALLQAEADGLRQEVICLKEHLS 1281
               .|.|..                         |:.:|.:......::|..|:.|::. ||:|
pombe  1298 ---YKRHNQ-------------------------EILLSLNSSTSTSSDASRLKNELVS-KENL- 1332

  Fly  1282 PSTDSDSLRSLNE---RLQRELEDLKHKSAGAESNM---QQEIEELQANN--------------- 1325
                   :..||:   .|:.|||.:|.||...|:..   |.:||:|:..|
pombe  1333 -------IEELNQEIGHLKSELETVKSKSEDLENERAQNQSKIEQLELKNTKLAAAWRTKYEQVV 1390

  Fly  1326 -----------QQMAERINELETLRAGIQAQQLLASM-APKNVQEAAAAGE------------KA 1366
                       ||::::.:|||...|  :..||...: .|.....|....|            |.
pombe  1391 NKSLEKHNQIRQQLSQKTSELEAKVA--ECHQLNEQLNKPSATPTATTQSEPSTVSLEEFNSTKE 1453

  Fly  1367 ELES---KLKEIMN-------EVQDV---------TNRNLFL--EQKCENFLILE---------- 1400
            ||.|   ||.|||:       |::.|         |:::..:  |::.|...:::
pombe  1454 ELSSTQRKLSEIMDILNTTKEELEKVRQNSNKSEGTSKDTEIPNEEEMERKKVMQQEVLRLRSRI 1518

  Fly  1401 ----QSNERLKLQNAKLSRQ---LDETLVSMQHSEAVPANTEFEYLRN---------IMFQYLTG 1449
                |.||.|:.||..|..|   |.||:||.:.:|:...:.:.:.|.|         :.||.:.
pombe  1519 AKELQKNELLRKQNQVLQDQVKALQETVVSSEEAESASVHADTKDLENLKKTEEMLSVTFQVIF- 1582

  Fly  1450 NTNNETLVKVISAVLKFSPQQAQVALEKE-HQRRSLLNK 1487
               ||::....::...|:     ..::|| .:||.:|.|
pombe  1583 ---NESISDFSTSTADFT-----TFVQKEWEKRREILQK 1613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Golgin245	NP_611787.2	Smc	286..1089	CDD:224117	211/931 (23%)
		Phage_GPO	<306..421	CDD:301727	31/157 (20%)
		Smc	737..1442	CDD:224117	188/853 (22%)
		MIT_CorA-like	<1244..>1333	CDD:294313	25/120 (21%)
		Grip	1433..1477	CDD:197860	7/52 (13%)
alm1	NP_594092.1	Smc	84..885	CDD:224117	196/893 (22%)
		SMC_prok_B	764..1567	CDD:274008	197/893 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100282
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900