Protein Alignment Mthfs and FAU1

DIOPT Version :10

• Sequence 1: NP_001097432.1
• Gene: Mthfs / 37699
• FlyBaseID: FBgn0085453
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_011110.1
• Gene: FAU1 / 856932
• SGDID: S000000985
• Length: 211
• Species: Saccharomyces cerevisiae
• Alignment Length: 213
• Identity: 60/213 - (28%)
• Similarity: 102/213 - (47%)
• Gaps: 39/213 - (18%)

  Fly    10 KVALRKRMKDALKGIDAEAIARQSQAVTAKVLQSEIFRQAQRVSIYLS-TASELDTTALLSEMFR 73
            |..||:::|..:..:|.:.||.:|..::..|........::||:.|:| ...|:.|..::..:|:
Yeast     4 KQLLRRQIKRVINALDYDIIAAESHTISQAVRSLIASANSRRVACYMSMDKGEVTTGEIIKNLFQ 68

  Fly    74 LEKMVFVP----TYEG------------------SRMKMVRLRGMEEYESLPLTKWNIKQPDFKE 116
            ..:.||:|    |.|.                  |.:||||       :..|...:.:|:|:...
Yeast    69 DGQEVFLPRCTHTSESKHFKLREDHHPHLIFHRMSSLKMVR-------DLKPQGPYQLKEPEPHI 126

  Fly   117 AREDAMTNGHGIDLFIVPGVAF-TRCGARMGHGMGYYDKFLKQHAEKYPHKKISLMALSLNEQIV 180
            ...|.      :|:.:|||||| .:.|||||||.||||.|.:::...:..:|..|:.|.|.||:.
Yeast   127 EESDI------LDVVLVPGVAFDIKTGARMGHGAGYYDDFFQRYKILHEGQKPLLVGLCLMEQVA 185

  Fly   181 SNEELPMESHDVRLHSVI 198
            |  .:|:|.||..:..::
Yeast   186 S--PIPLEKHDYSMDCIV 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mthfs	NP_001097432.1	FAU1	10..201	CDD:439982	60/213 (28%)
FAU1	NP_011110.1	5-FTHF_cyc-lig	4..203	CDD:396398	60/213 (28%)