Protein Alignment Mthfs and Mthfs

DIOPT Version :10

• Sequence 1: NP_001097432.1
• Gene: Mthfs / 37699
• FlyBaseID: FBgn0085453
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_001009349.1
• Gene: Mthfs / 300886
• RGDID: 1306876
• Length: 203
• Species: Rattus norvegicus
• Alignment Length: 205
• Identity: 76/205 - (37%)
• Similarity: 124/205 - (60%)
• Gaps: 10/205 - (4%)

  Fly     1 MAATIQNTLKVALRKRMKDALKGIDAEAIARQSQAVTAKVLQSEIFRQAQRVSIYLSTASELDTT 65
            |||...|:.|..||..:|..|:.:.||...|||..:|.||:....::.::|:||:||...|::|.
  Rat     1 MAAVTVNSAKRGLRAELKQRLRALGAEERLRQSHLLTQKVIAHSQYQNSKRISIFLSMQDEIETE 65

  Fly    66 ALLSEMFRLEKMVFVPTYE--GSRMKMVRLRGMEEYESLPLTKWNIKQPDFKEAREDAMTNGHGI 128
            .::.::|:..|:.|:|.|:  .:.|.||||...||...||.|.|||.||...:.||:|::.| |:
  Rat    66 EIIKDIFKQGKICFIPRYQFHSNHMDMVRLTAPEEVALLPKTSWNIHQPGEGDVREEALSTG-GL 129

  Fly   129 DLFIVPGVAFTRCGARMGHGMGYYDKFLKQHAEKYPHKKIS--LMALSLNEQIVSNEELPMESHD 191
            ||..:||:.|.:.|.|:|.|.||||.:||:..:   |:|:.  .:||:..|||.  .::|::.||
  Rat   130 DLIFLPGLGFDKDGNRLGRGKGYYDTYLKRCVQ---HQKVKPYTLALAFREQIC--PQIPVDEHD 189

  Fly   192 VRLHSVITEN 201
            :::..|:.|:
  Rat   190 MKVDEVLYED 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mthfs	NP_001097432.1	FAU1	10..201	CDD:439982	71/194 (37%)
Mthfs	NP_001009349.1	5-FTHF_cyc-lig	10..198	CDD:396398	70/191 (37%)