Protein Alignment Mthfs and Mthfsl

DIOPT Version :10

• Sequence 1: NP_001097432.1
• Gene: Mthfs / 37699
• FlyBaseID: FBgn0085453
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_001122073.1
• Gene: Mthfsl / 100039707
• MGIID: 3780550
• Length: 203
• Species: Mus musculus
• Alignment Length: 206
• Identity: 79/206 - (38%)
• Similarity: 123/206 - (59%)
• Gaps: 12/206 - (5%)

  Fly     1 MAATIQNTLKVALRKRMKDALKGIDAEAIARQSQAVTAKVLQSEIFRQAQRVSIYLSTASELDTT 65
            |||...|:.|..||..:|..|:.:.||...|||..:|.||:....::.::|:||:||...|::|.
Mouse     1 MAAVTVNSAKRGLRAELKQRLRALSAEERLRQSLLLTQKVIAHNQYQNSKRISIFLSMQDEVETE 65

  Fly    66 ALLSEMFRLEKMVFVPTY--EGSRMKMVRLRGMEEYESLPLTKWNIKQPDFKEAREDAMTNGHGI 128
            .::.::|:..|:.|:|.|  :.:.|.||||...||...||.|.|||.||...:.||:|::.| |:
Mouse    66 VIIKDIFKQGKICFIPQYQFQSNHMDMVRLTSPEEIALLPKTSWNIHQPGEGDVREEALSTG-GL 129

  Fly   129 DLFIVPGVAFTRCGARMGHGMGYYDKFLK---QHAEKYPHKKISLMALSLNEQIVSNEELPMESH 190
            ||..:||:.|.:.|.|:|.|.||||.:||   ||.|..|:    .|||:..|||.  .::|::.|
Mouse   130 DLIFLPGLGFDKDGNRLGRGKGYYDTYLKRCVQHQEVKPY----TMALAFKEQIC--PQIPVDEH 188

  Fly   191 DVRLHSVITEN 201
            |:::..|:.|:
Mouse   189 DMKVDEVLYED 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mthfs	NP_001097432.1	FAU1	10..201	CDD:439982	74/195 (38%)
Mthfsl	NP_001122073.1	5-FTHF_cyc-lig	10..198	CDD:396398	74/194 (38%)