Protein Alignment CG3502 and AAP1

DIOPT Version :10

• Sequence 1: NP_611781.3
• Gene: CG3502 / 37695
• FlyBaseID: FBgn0046253
• Length: 912
• Species: Drosophila melanogaster
• Sequence 2: NP_011913.1
• Gene: AAP1 / 856443
• SGDID: S000001089
• Length: 856
• Species: Saccharomyces cerevisiae
• Alignment Length: 911
• Identity: 255/911 - (27%)
• Similarity: 419/911 - (45%)
• Gaps: 123/911 - (13%)

  Fly    30 LPRSVEPLHY------NLRILTHLNSTDQRFEGSVTIDLLARETTKNITLHAAYLKIDENRTSVV 88
            ||.:|.||||      |.|..|        ||||:.|||...:.:.| ::...||:||.:...:.
Yeast     6 LPNNVTPLHYDITLEPNFRAFT--------FEGSLKIDLQINDHSIN-SVQINYLEIDFHSARIE 61

  Fly    89 SGQEKFGVNRIEVNEVHNFY----------ILHLGRELVKDQIYKLEMHFKAGLNDSQSGYYKSN 143
                  |||.||||:..|..          ..:||...      |||:.|...|||..:|:|::.
Yeast    62 ------GVNAIEVNKNENQQKATLVFPNGTFENLGPSA------KLEIIFSGILNDQMAGFYRAK 114

  Fly   144 YTDIVTKEVHHLAVTQFSPTFARQAFPCFDEPSWKATFNITLGYHKKYMGLSGMPVLR--CQDHD 206
            |||.||.|..::|.||...|.||:||||||||:.||||.:||........||.|.|..  .::..
Yeast   115 YTDKVTGETKYMATTQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRNETIKEGK 179

  Fly   207 SLTNYVWCDHDTLLRTSTYLVAFAVHDLENAATEESKTSN-RVIFRNWMQPKLLGQE---MISME 267
            ..|.:     :|..:.|||||||.|.||...     :::| |:..|.:..|   |.|   ..:..
Yeast   180 KYTTF-----NTTPKMSTYLVAFIVADLRYV-----ESNNFRIPVRVYSTP---GDEKFGQFAAN 231

  Fly   268 IAPKLLSFYENLFQINFPLAKVDQLTVPTHRFT--AMENWGLVTYNEERLPQNQGDYPQKQKDST 330
            :|.:.|.|:|:.|.|.:||.|:|.:.|  |.|:  ||||||||||....|..:..:....:....
Yeast   232 LAARTLRFFEDTFNIEYPLPKMDMVAV--HEFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRV 294

  Fly   331 AFTVAHEYAHQWFGNLVTMNWWNDLWLKEGPSTYFGYLALDSLQPEWRRGERFISRDLANFFSKD 395
            |..:.||.|||||||||||:||..|||.||.:|:..:.:.:..||||:..|::::.:|....:.|
Yeast   295 AEVIQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRALNLD 359

  Fly   396 SNATVPAISKDVKNPAEVLGQFTEYVYEKGSLTIRMLHKLVGEEAFFHGIRSFLERFSFGNVAQA 460
            |..:...|...|.|..|:...|....|.|||..:||:.|.:|||.|..|:..:|.:|.:||....
Yeast   360 SLRSSHPIEVPVNNADEINQIFDAISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTG 424

  Fly   461 DLWNSLQMAALKNQVISSDFNLSRAMDSWTLQGGYPLVTLIRNYKTGEVTLNQSRFFQEHGIEKA 525
            |||::|..|:.|        ::...|:.||.:.|:|::: ::.:| .::||.|.|:.....:::.
Yeast   425 DLWDALADASGK--------DVCSVMNIWTKRVGFPVLS-VKEHK-NKITLTQHRYLSTGDVKEE 479

  Fly   526 SSCWWVPLRFVRQNLPDFNQTTPQFWLECPLNTKVLKLPDHLSTDEWVILNPQVATIFRVNYDEH 590
            ......|:....::....:.|       ..||.|....  .|..:|:..:|...:.||..:|.:.
Yeast   480 EDTTIYPILLALKDSTGIDNT-------LVLNEKSATF--ELKNEEFFKINGDQSGIFITSYSDE 535

  Fly   591 NWRLIIESLRNDPNSGGIHKLNKAQLLDDLMALAAVRLHKYDKAFDLLEYLKKEQDFLPWQRAIG 655
            .|    ..|....|...:.  ::..|:.|..||:|..........:|:...|.|..|:.|::
Yeast   536 RW----AKLSKQANLLSVE--DRVGLVADAKALSASGYTSTTNFLNLISNWKNEDSFVVWEQ--- 591

  Fly   656 ILNRLGALLN--VAEANKFKNYMQKLLLPL-YNRFPKLS---------GIREAKPAIKDIPFAHF 708
            |:|.|.||.:  |.|.....|.:.|..|.| .|:..:|.         .|:..|..:
Yeast   592 IINSLSALKSTWVFEPEDILNALDKFTLDLVLNKLSELGWNIGEDDSFAIQRLKVTL-------- 648

  Fly   709 AYSQACRYHVADCTDQAKILAI----THRTEGQLELPSDFQKVAYCSLLDEGGDAEFLEVFGLFQ 769
             :|.||    ....::.:.:|:    .:....:..:|:.|:.|.:.::...||:..:.::|.::|
Yeast   649 -FSAAC----TSGNEKMQSIAVEMFEEYANGNKQAIPALFKAVVFNTVARLGGENNYEKIFNIYQ 708

  Fly   770 NSTNGSQRRILASALGCVRNFGNFEQFLNYTLESDEKLLGDCYMLAVKSALNREPLVSPTANYII 834
            |..:..::.|...|||...:....|:.|:|.|  |..:|...:.:.::.....:..:.....::.
Yeast   709 NPVSSEEKIIALRALGRFEDKELLERTLSYLL--DGTVLNQDFYIPMQGIRVHKKGIERLWAWMQ 771

  Fly   835 SHAKKLGEKFK--KKELTGLLLSLAQNLRSTEEIDRLKA--QLEDLKEFEEPLKKALYQGKMNQK 895
            .|..::.::.:  ...|.|:|.....|..|.|.::::.|  ..:..|.|::.|.:||...:...:
Yeast   772 EHWDEIAKRLQPGSPVLGGVLTLGLTNFTSFEALEKISAFYSRKVTKGFDQTLAQALDTIRSKAQ 836

  Fly   896 W 896
            |
Yeast   837 W 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3502	NP_611781.3	M1_APN-Q_like	37..491	CDD:341064	168/477 (35%)
		ERAP1_C	572..887	CDD:463368	65/334 (19%)
AAP1	NP_011913.1	M1_APN-Q_like	13..447	CDD:341064	168/477 (35%)
		ERAP1_C	517..833	CDD:463368	67/339 (20%)