Protein Alignment CG3502 and Lta4h

DIOPT Version :10

• Sequence 1: NP_611781.3
• Gene: CG3502 / 37695
• FlyBaseID: FBgn0046253
• Length: 912
• Species: Drosophila melanogaster
• Sequence 2: NP_001025202.1
• Gene: Lta4h / 299732
• RGDID: 1311333
• Length: 611
• Species: Rattus norvegicus
• Alignment Length: 672
• Identity: 154/672 - (22%)
• Similarity: 250/672 - (37%)
• Gaps: 158/672 - (23%)

  Fly    31 PRSV-EPLHYNLRILTHLNSTD---QRFEGSVTIDLLARE-TTKNITLHAAYLKIDENRTSVVSG 90
            |.|| ...|.:||.     |.|   :...|:..:.:.::| ..:::||....|.|::   .|::|
  Rat    13 PASVCRTQHLHLRC-----SVDFARRALTGTAALTVQSQEDNLRSLTLDTKDLTIEK---VVING 69

  Fly    91 QE-KFGVNR--------IEVNEVHNFYILHLGRELVKDQIYKLEMHFKAGLNDSQSGYYKSNYTD 146
            || |:.:..        :|::         |...|.|:|...:|:.|:.....|...:.....|
  Rat    70 QEVKYTLGESQGYKGSPMEIS---------LPIALSKNQEVVIEISFETSPKSSALQWLTPEQT- 124

  Fly   147 IVTKEVHHLAVTQFSPTFARQAFPCFDEPSWKATFNITLGYHKKYMGLSGMPVLR---CQDHDSL 208
              :.:.|....:|......|...||.|.||.|.|:...:...|:.:.|  |..:|   ..|.:..
  Rat   125 --SGKQHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVAL--MSAIRDGEAPDPEDP 185

  Fly   209 TNYVWCDHDTLLRTSTYLVAFAVHDLENAATEESKTSNRVIFRNWMQPKLLGQEMISMEIAPKLL 273
            :..:: ..:..:....||:|..|     .|.|..:...|.:.  |.:.:.:.:..........:|
  Rat   186 SRKIY-RFNQRVPIPCYLIALVV-----GALESRQIGPRTLV--WSEKEQVEKSAYEFSETESML 242

  Fly   274 SFYENLFQINFPLAKVDQLTV-PTHRFTAMENWGLVTYNEERLPQNQGDYPQKQKDSTAFTVAHE 337
            ...|:|.. .:...:.|.|.: |:..:..|||..|.......|   .||      .|.:..:|||
  Rat   243 KIAEDLGG-PYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLL---AGD------KSLSNVIAHE 297

  Fly   338 YAHQWFGNLVTMNWWNDLWLKEGPSTYFGYLALDSLQPEWRRGERFISRDLANFFSKDSNATVPA 402
            .:|.|.|||||...|:..||.||.:.|.               ||.|...|  |..|..:.....
  Rat   298 ISHSWTGNLVTNKTWDHFWLNEGHTVYL---------------ERHICGRL--FGEKFRHFHALG 345

  Fly   403 ISKDVKNPAEVLGQ---FTEYV----------------YEKGSLTIRMLHKLV-GEEAFFHGIRS 447
            ...:::|..:..|:   ||:.|                ||||...:..|.:|: |.|.|...:::
  Rat   346 GWGELQNTIKTFGESHPFTKLVVDLKDVDPDVAYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKA 410

  Fly   448 FLERFSFGNVAQADLWNSLQMAALKNQVISSDFNLSRAMD--SWTLQGGYPLVTLIRNYKTGEVT 510
            ::|:||:.:|...| |.|...|..|::|     :|...:|  :|....|.|.|.  .||   :||
  Rat   411 YVEKFSYQSVTTDD-WKSFLYAHFKDKV-----DLLNQVDWNAWLYAPGLPPVK--PNY---DVT 464

  Fly   511 LNQSRFFQEHGIEKASSCWWVPLR------FVRQNLPD-----FNQTTPQFWLECPLNTKVLKLP 564
            |..:..        |.|..||..:      |..::|.|     .|:...|...:.||....:|..
  Rat   465 LTNACI--------ALSQRWVTAKEEDLNSFSIEDLKDLSSHQLNEFLAQVLQKAPLPLGHIKRM 521

  Fly   565 DHLSTDEWVILNPQVATIFRVNYDE--HNW-RLIIES---------LRNDPNSGGIHKLNKAQLL 617
            .            :|.....:|..|  ..| ||.|:|         |:.....|.: |..: .|.
  Rat   522 Q------------EVYNFNAINNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRM-KFTR-PLF 572

  Fly   618 DDLMAL-----AAVRLHKYDKA 634
            .||.|.     .|||.::..||
  Rat   573 KDLAAFDKSHDQAVRTYQEHKA 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3502	NP_611781.3	M1_APN-Q_like	37..491	CDD:341064	111/492 (23%)
		ERAP1_C	572..887	CDD:463368	20/80 (25%)
Lta4h	NP_001025202.1	leuko_A4_hydro	6..608	CDD:274120	154/672 (23%)