Protein Alignment CG3502 and LOC11175889

DIOPT Version :10

• Sequence 1: NP_611781.3
• Gene: CG3502 / 37695
• FlyBaseID: FBgn0046253
• Length: 912
• Species: Drosophila melanogaster
• Sequence 2: XP_003436573.2
• Gene: LOC11175889 / 11175889
• VectorBaseID: AGAMI1_012506
• Length: 935
• Species: Anopheles gambiae
• Alignment Length: 944
• Identity: 250/944 - (26%)
• Similarity: 414/944 - (43%)
• Gaps: 117/944 - (12%)

  Fly    14 FLILVPSIRAVYEDYRLPRSVEPLHYNLRILTHL----NSTDQRFEGSVTIDL-LARETTKNITL 73
            :.::.|..||..|||||...|.|.||::.|..:|    |.....|:||..|.: ..::....|.|
Mosquito    31 YFLVEPEPRAQPEDYRLNDDVWPTHYDIEIKPYLEQEGNKAQFTFDGSAKITVSTQKQNVMQIKL 95

  Fly    74 HAAYLKIDENRTSVVSGQEKFGVNRI--EVNEVHNFYILHLGRELVKDQIYKLEMHFKAGLNDSQ 136
            |.|  ::|....||....:...:..:  ..::......|.|...|..:..|.|...:...::|..
Mosquito    96 HMA--RMDITAWSVTRKSDNTIIPTLPQTYDQETQILTLPLSSALQANVEYVLSFTYVGNMDDDM 158

  Fly   137 SGYYKSNYTDIVTKEVHHLAVTQFSPTFARQAFPCFDEPSWKATFNITLGYHKKYMGLSGMPVLR 201
            .|:|:|.|.:...|.  .:..|||..|.||:||||||||.:||||.:.:.:..:|...|...::.
Mosquito   159 HGFYRSYYWEDGVKV--WMGSTQFQQTHARRAFPCFDEPRFKATFQLKINHKTQYNVYSNTAIVG 221

  Fly   202 ---CQDHDSLTNYVWCDHDTLLRTSTYLVAFAVHDLENAATEESKTSNRVIFRNWM----QPKLL 259
               .:...:||.:     ......|:||:||.|            ...::..|:.|    :|:..
Mosquito   222 TAVAEVGRTLTTF-----GVTPSMSSYLIAFIV------------APYQINDRDGMGILARPQAQ 269

  Fly   260 GQEMISMEIAPKLLSFYENLFQINFPLAKVDQLT------VPTHRFTAMENWGLVTYNEERLPQN 318
            .|...|:::..|||...|.  .|::|.|.|..:|      ||.....|||||||:||.|..:...
Mosquito   270 NQTQYSLDVGIKLLKALEE--WIDYPYASVAGMTRMYMAAVPDFSAGAMENWGLLTYRETNILYR 332

  Fly   319 QGDYPQKQKDSTAFTVAHEYAHQWFGNLVTMNWWNDLWLKEGPSTYFGYLALDSLQPEWRRGERF 383
            ..|....|:...|..::||.||||||:|||..||:..||.||.:.|:.|.....::.||....:|
Mosquito   333 SDDSTSMQQHRIAAVISHEIAHQWFGDLVTCEWWDVTWLNEGFARYYQYYGTALVETEWNLDHQF 397

  Fly   384 ISRDLANFFSKDSNATVPAISKDVKNPAEVLGQFTEYVYEKGSLTIRMLHKLVGEEAFFHGIRSF 448
            :...|......||..:...::..|...|:..|.|....|.||::.:||:...:..|.|...:|::
Mosquito   398 VVEQLQGVMQMDSLRSTHPMTHPVYTQAQASGIFDNISYNKGAVMLRMMEHYLTTETFKTALRAY 462

  Fly   449 LERFSFGNVAQADLWNSLQMAALKNQVISSDFNLSRAMDSWTLQGGYPLVTLIRNYKTGEVTLNQ 513
            ::..:|......||:::|.         ..|.|....|:.||:|.|||||| :.::.|| .|:.|
Mosquito   463 IKDRAFKTTRPEDLFSALN---------RYDPNARSYMEPWTIQSGYPLVT-VTSHDTG-FTITQ 516

  Fly   514 SRFFQEHGIEKASSCWWVPLRFVRQNLPDFNQTTPQFWLECPLNTKVLKLPDHLSTD-EWVILNP 577
            .||............|.:|:.|..: ..:|:.|.|.|:     .....::|...::| |:.|||.
Mosquito   517 KRFLVNEPDHNEQIAWPLPITFATK-ASEFSITRPAFY-----TGMTFEIPMQGASDVEYFILNN 575

  Fly   578 QVATIFRVNYDEHNWRLIIESLRNDPNSGGIHKLNKAQLLDDLMALAAVRLHKYDKAFDLLEYLK 642
            |....:|||||...|..|.::|.:: ..||||.||:||::|||..||...:..|..|.::|||||
Mosquito   576 QQVGYYRVNYDAILWGKISKALHSE-GFGGIHVLNRAQIVDDLFNLARGDVVPYGTALEILEYLK 639

  Fly   643 KEQDFLPWQRAIGILNRLGALLNVAEANKFKNYMQKLLLPLYN--RFPKLSGIREAKPAIKDIPF 705
            :|.::.||..|:..|..|...::..:...|..::..:....|:  :|       :|..|.:...|
Mosquito   640 EETEYAPWLAAVNGLTTLSRRIHADDEKLFAAHILDIFSKAYDIVKF-------QAPTATERRIF 697

  Fly   706 AHF---AYSQACRYHVADCTDQAKILAITHR--TEGQLELPSDFQKVAYCSLLDEGGDAEFLEVF 765
            .:.   ....||.|...:|:..|  :|..||  ....:::..|.::|.||..:.:|...||..::
Mosquito   698 TYMRQNVLQWACNYGHEECSKAA--VAEFHRYHQNPSVKVHPDLRQVVYCEGIRKGSTEEFEFLW 760

  Fly   766 GLFQNSTNGSQRRILASALGCVRNFGNFEQFLNYT----LESDEKLLGDCYMLAVKSALNREPLV 826
            ..:..:...:::.::...||||.:.......||..    :.|.:|.....|::       ..|..
Mosquito   761 NQYLTTNVATEQILILQGLGCVSSSELITDMLNGIASPHVRSQDKNNAFTYVI-------NNPYT 818

  Fly   827 SP---------TANYIISHAK--KLGEKFKKKELTGLLLSLAQNLRSTEEIDRLKAQLEDLKEF- 879
            .|         .||:..||..  .:...|.         ::...|:|..|.|.:.|.:|..|..
Mosquito   819 LPHVSRYLQQNHANWAASHGSYTNVASAFN---------NVLARLKSDSERDAISAFIESNKNIL 874

  Fly   880 ----EEPLKKALYQGKMNQKW---QKDCSSDFIE 906
                .:.:|..|...:.|:::   .:|...:|::
Mosquito   875 GQAAYDSIKSGLEDYETNKQFTLRNRDEIHEFLD 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3502	NP_611781.3	M1_APN-Q_like	37..491	CDD:341064	129/473 (27%)
		ERAP1_C	572..887	CDD:463368	83/341 (24%)
LOC11175889	XP_003436573.2	None