Protein Alignment Prosbeta5R1 and PSMB5

DIOPT Version :10

• Sequence 1: NP_611776.1
• Gene: Prosbeta5R1 / 37690
• FlyBaseID: FBgn0034842
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_002788.1
• Gene: PSMB5 / 5693
• HGNCID: 9542
• Length: 263
• Species: Homo sapiens
• Alignment Length: 231
• Identity: 126/231 - (54%)
• Similarity: 168/231 - (72%)
• Gaps: 10/231 - (4%)

  Fly    43 LMAPPFERPAENLPKILSHCGIRMDFDHGTTTLGFKYRGGVILCADSRATSGQYIGSQTMRKIVE 107
            |.||.:..|.|.        ||.|  .||||||.||:|.|||:.||||||:|.||.|||::|::|
Human    41 LAAPGWGVPEEP--------GIEM--LHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIE 95

  Fly   108 LNDYMLGTLAGGAADCVYWDRVLAKECRLHQLRYRKRMTVDTAARIICNISTEYKGMGLVMGMML 172
            :|.|:|||:|||||||.:|:|:||::||:::||.::|::|..|::::.|:..:||||||.||.|:
Human    96 INPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMI 160

  Fly   173 AGFDDEGPKLIYVDSEGMRSHGQVFSVGSGSPYALGVLDTGYRYDLSDQEAYDLARRAIYHATSK 237
            .|:|..||.|.||||||.|..|..|||||||.||.||:|.||.|||..::||||||||||.||.:
Human   161 CGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYR 225

  Fly   238 DAYSGGIVRLYHIHSEGWRNICNTDCSDLHDSYCAS 273
            ||||||.|.|||:..:||..:.:.:.:|||:.|..|
Human   226 DAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGS 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5R1	NP_611776.1	proteasome_beta_type_5	72..259	CDD:239730	111/186 (60%)
PSMB5	NP_002788.1	proteasome_beta_type_5	60..247	CDD:239730	111/186 (60%)