Protein Alignment CG12782 and bub-3

DIOPT Version :10

• Sequence 1: NP_611772.2
• Gene: CG12782 / 37685
• FlyBaseID: FBgn0034838
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_496879.1
• Gene: bub-3 / 175018
• WormBaseID: WBGene00013209
• Length: 343
• Species: Caenorhabditis elegans
• Alignment Length: 322
• Identity: 87/322 - (27%)
• Similarity: 141/322 - (43%)
• Gaps: 41/322 - (12%)

  Fly    14 DYELPNPPNDTISALEFSPRSSSWNAICAGSWDNTVRIWEVQADRLVPKVMNSLEGTPFDVTWND 78
            ::.:|.||...||.::|. |.:....:.|..||.|.|::||.....:.:.:....|.|. :|...
 Worm    15 EFRVPFPPFVQISKVQFQ-REAGSRLLAASGWDGTCRVYEVGKLGDISEKLVFTHGKPL-LTCTF 77

  Fly    79 SG-NKVYLSDSSGQVTEWDLESNQLRKVGLHARAARTCHWVGP---YLATTSWDKSIRFWDPRA- 138
            :| |||........|...|:|:....::|.||.|.| |....|   .:.:..||.|::.||.|:
 Worm    78 AGYNKVAFGGVDHNVKLADIETGNGTQLGSHALAVR-CMEFNPMSSLIVSGGWDSSVKLWDARSY 141

  Fly   139 ---AIELTRMELPDRSYAADVLNDVAVVACGDRSILAYTLRGGPVEQGRMKSPGESNTQVRSVAL 200
               |||  .:.:....||.|||....:|...||.|..|..|       :::.|    .|||...|
 Worm   142 GNGAIE--SVNVSSSVYAMDVLKHTILVGTKDRKIFMYDSR-------KLREP----LQVRDSPL 193

  Fly   201 -HQNRDL------TSWLIAKTNGMV----FDQS---MAHRTVSFPIRCHR-RENSGILDVYAVNE 250
             :|.|.:      .:::::...|.|    .|||   |..|..:|  :||| ::..|...::.|:.
 Worm   194 KYQTRAVQFFPTGEAFVVSSIEGRVAVEYVDQSGEEMMKRKYAF--KCHREKDTDGTELIHPVHT 256

  Fly   251 VKVNMVTQHIATVGSDGVFCFWDSQMRSKLLESKVHPQPITKCAISGDGKLFAYALGYDWSK 312
            |..:......||.|:||:...||...|.::::.......|:..:.:.||...|.|..|.:.|
 Worm   257 VAFHPKYGTFATGGADGIVNIWDPFNRKRIIQLHKFETSISSLSFNEDGSQLAIATSYQYEK 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12782	NP_611772.2	WD40	25..303	CDD:475233	80/300 (27%)
		WD40 repeat	26..64	CDD:293791	10/37 (27%)
		WD40 repeat	71..101	CDD:293791	9/30 (30%)
		WD40 repeat	109..146	CDD:293791	14/43 (33%)
		WD40 repeat	195..235	CDD:293791	13/53 (25%)
		WD40 repeat	242..272	CDD:293791	7/29 (24%)
bub-3	NP_496879.1	WD40	37..309	CDD:475233	76/288 (26%)
		WD40 repeat	73..107	CDD:293791	8/33 (24%)
		WD40 repeat	112..148	CDD:293791	12/38 (32%)
		WD40 repeat	156..190	CDD:293791	14/44 (32%)
		WD40 repeat	197..238	CDD:293791	9/42 (21%)
		WD40 repeat	254..288	CDD:293791	10/33 (30%)