Protein Alignment LS2 and MUD2

DIOPT Version :10

• Sequence 1: NP_611769.2
• Gene: LS2 / 37681
• FlyBaseID: FBgn0034834
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_012849.1
• Gene: MUD2 / 853788
• SGDID: S000001557
• Length: 527
• Species: Saccharomyces cerevisiae
• Alignment Length: 474
• Identity: 104/474 - (21%)
• Similarity: 174/474 - (36%)
• Gaps: 124/474 - (26%)

  Fly     3 RFRPMNRSWNALRSR-SRSRSRSRSPFRSQSITRSRPT-RSDTIYTERTRLQRRFSRPPSSWDIP 65
            ||....|:.|....| :..|....|.|......|...| :.|..|..:..:.     |.||:| .
Yeast   136 RFDRRGRNGNGNYDRFNYQRKNEGSKFNGDRDKRQLQTNKYDMNYNSQNVMY-----PGSSFD-S 194

  Fly    66 PEGYNHLTPQQYKAMLASGQIASRILSDGVHGGESAAISMITRQARRL--YVGNIPFGVTDEEMM 128
            |..||          :||.:..||::..|:  .:|:..|::.|....|  ::..:....::.|..
Yeast   195 PAYYN----------MASSKANSRLVISGL--SQSSDPSIVARLKDLLENFISGLQKTESNAEDF 247

  Fly   129 QFFNHQIMALGFEAKSSHYMDGNAVLTCQTNLEKNFAFLEFRSIDEASQALNFDGMVFRGQTLKI 193
            :..|..|    .|.:..|.:...:...|.|.:      |..||...|... .||        ||.
Yeast   248 KISNFYI----GEGRPDHIIVEFSSQICSTMV------LACRSFFNAKLG-TFD--------LKW 293

  Fly   194 RRPHDY-QPVPSI------SVSAMESYRSFRVPAINVAQQPAVTLPVTTIVPDSPNKIYVGGLPT 251
            |||:|| |.:..:      :|.|:|:..       |:.:
Yeast   294 RRPNDYVQQLDHLVDFCRGTVIALENLE-------NIGE-------------------------- 325

  Fly   252 CLNQD-QVKELLQSF----GELKGLNLVMDTNTNLNKGFAFFEYCDPSVTDHAIAGLHGMLLGDR 311
              .:| ::|||..|.    |..|.|.....:|||.....:.|..|              :||...
Yeast   326 --GEDYRMKELFSSLNVTNGTAKPLFYKCSSNTNNTGKESEFTKC--------------ILLSFE 374

  Fly   312 RLVVQRSIPGGKNAFPGHLPT---VLQVPGISTLQD-PGSPTET-------LCLLNMVRPEELLD 365
              ||.:.|......:....|.   :.||....|.|. |...|::       |.|||.:.|.:|.|
Yeast   375 --VVTQDILDKLKPYKWFKPNDGKISQVTSWITFQSLPNLVTQSVRVESRVLLLLNCLDPLDLKD 437

  Fly   366 DEEFEDIRTDIKQECAKFGEVRSIKIPRPIGQFP------KRGCGKVFVQFESVEDSQKALKALS 424
            :....:|:..:|...|   ...:|||.:|...:.      ..|.|.::::|:::|.::.|::.|.
Yeast   438 ETFITEIKETLKYSIA---GADTIKICQPGVDYRLNFENLASGAGNIYIKFKTLEAAKHAMEELP 499

  Fly   425 GRKFSGRIVMTSYYDPEKY 443
            |.:|:.|.|:.:|.|.:.:
Yeast   500 GTQFNDRTVLCTYIDEDDF 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LS2	NP_611769.2	U2AF_lg	35..447	CDD:273727	96/441 (22%)
MUD2	NP_012849.1	PRK12678	<46..>156	CDD:237171	5/19 (26%)
		RRM_1	436..511	CDD:214637	18/77 (23%)