Protein Alignment LS2 and U2af50

DIOPT Version :9

• Sequence 1: NP_611769.2
• Gene: LS2 / 37681
• FlyBaseID: FBgn0034834
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001245708.1
• Gene: U2af50 / 32602
• FlyBaseID: FBgn0005411
• Length: 427
• Species: Drosophila melanogaster
• Alignment Length: 437
• Identity: 240/437 - (54%)
• Similarity: 297/437 - (67%)
• Gaps: 33/437 - (7%)

  Fly    12 NALRSRSRSRSRSRSPFRSQSITRSRPTRSDTIYTERTRLQRRFSRPPSSWDIPPEGYNHLTPQQ 76
            |..|.|.|.|.|.||..|.:...|||..|       ..|..||  :|...||:||.|:.|:||.|
  Fly    14 NKDRERDRERRRHRSRSRDRHRERSRDRR-------HHRNSRR--KPSLYWDVPPPGFEHITPMQ 69

  Fly    77 YKAMLASGQIASRILSDGVHGGESAAISMITRQARRLYVGNIPFGVTDEEMMQFFNHQIMALGFE 141
            ||||.|||||.:.::.|..........|.||||||||||||||||||:||||:|||.|:..:|..
  Fly    70 YKAMQASGQIPASVVPDTPQTAVPVVGSTITRQARRLYVGNIPFGVTEEEMMEFFNQQMHLVGLA 134

  Fly   142 AKSSHYMDGNAVLTCQTNLEKNFAFLEFRSIDEASQALNFDGMVFRGQTLKIRRPHDYQPVPSIS 206
            ..:     |:.||.||.||:|||||||||||||.:||:.|||:..:||:|||||||||||:|.|:
  Fly   135 QAA-----GSPVLACQINLDKNFAFLEFRSIDETTQAMAFDGINLKGQSLKIRRPHDYQPMPGIT 194

  Fly   207 VSAMESYRSFRVPAINVAQQPAVTLP--VTTIVPDSPNKIYVGGLPTCLNQDQVKELLQSFGELK 269
                      ..|||    :|||...  ::|:|||||:||::||||..||.|||||||.|||:|:
  Fly   195 ----------DTPAI----KPAVVSSGVISTVVPDSPHKIFIGGLPNYLNDDQVKELLLSFGKLR 245

  Fly   270 GLNLVMDTNTNLNKGFAFFEYCDPSVTDHAIAGLHGMLLGDRRLVVQRSIPGGKNAFPGHLPT-- 332
            ..|||.|..|.|:||:||.||.|.|:||.:||||:||.|||::|:|||:..|.|||......|
  Fly   246 AFNLVKDAATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAKNAQNAANTTQS 310

  Fly   333 -VLQVPGISTLQDPGSPTETLCLLNMVRPEELLDDEEFEDIRTDIKQECAKFGEVRSIKIPRPIG 396
             :|||||:|.:...|.|||.|||||||.|:||.|:||:|||..|||:||.|:|.|||::|||||.
  Fly   311 VMLQVPGLSNVVTSGPPTEVLCLLNMVTPDELRDEEEYEDILEDIKEECTKYGVVRSVEIPRPIE 375

  Fly   397 QFPKRGCGKVFVQFESVEDSQKALKALSGRKFSGRIVMTSYYDPEKY 443
            .....|||||||:|.||.|.|||.:||:|||||.|:|:|||:||:||
  Fly   376 GVEVPGCGKVFVEFNSVLDCQKAQQALTGRKFSDRVVVTSYFDPDKY 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LS2	NP_611769.2	RRM1_U2AF65	110..196	CDD:240676	54/85 (64%)
		RRM2_U2AF65	242..318	CDD:240677	47/75 (63%)
		RRM3_U2AF65	349..436	CDD:240678	56/86 (65%)
U2af50	NP_001245708.1	RRM1_U2AF65	103..184	CDD:240676	54/85 (64%)
		RRM2_U2AF65	218..294	CDD:240677	47/75 (63%)
		RRM3_U2AF65	328..415	CDD:240678	56/86 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446147
Domainoid	1	1.000	47	1.000	Domainoid score	I4540
eggNOG	1	0.900	-	-		E1_KOG0120
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	282	1.000	Inparanoid score	I867
Isobase	1	0.950	-	0	Normalized mean entropy	S1673
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391481at33208
OrthoFinder	1	1.000	-	-		FOG0003153
OrthoInspector	1	1.000	-	-		mtm1083
orthoMCL	1	0.900	-	-		OOG6_101356
Panther	1	1.100	-	-	P	PTHR23139
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2550
	12	11.750