Sequence 1: | NP_066292.2 | Gene: | KCNJ12 / 3768 | HGNCID: | 6258 | Length: | 433 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001287485.1 | Gene: | Irk2 / 42770 | FlyBaseID: | FBgn0039081 | Length: | 454 | Species: | Drosophila melanogaster |
Alignment Length: | 407 | Identity: | 181/407 - (44%) |
---|---|---|---|
Similarity: | 254/407 - (62%) | Gaps: | 31/407 - (7%) |
- Green bases have known domain annotations that are detailed below.
Human 9 PYSIVSSEEDGLHLVTMSG----------ANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANMDEK 63
Human 64 SQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEP------AEGRGRTP 122
Human 123 CVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARP 187
Human 188 KKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDID 252
Human 253 VGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYL 317
Human 318 ANEILWGHRFEPVLFEEKN--QYKIDYSHFHKTYEVPSTPRCSAKDL-----VENKFLLPSANSF 375
Human 376 CYENELAFLSRDEEDEA 392 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
KCNJ12 | NP_066292.2 | IRK_N | 3..46 | CDD:312087 | 9/46 (20%) |
IRK | 47..374 | CDD:307239 | 166/339 (49%) | ||
Interaction with phosphatidylinositides. /evidence=ECO:0000250 | 79..81 | 0/1 (0%) | |||
Selectivity filter. /evidence=ECO:0000250 | 143..148 | 4/4 (100%) | |||
Interaction with phosphatidylinositides. /evidence=ECO:0000250 | 183..190 | 4/6 (67%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 387..433 | 2/6 (33%) | |||
PDZ-binding. /evidence=ECO:0000255 | 431..433 | ||||
Irk2 | NP_001287485.1 | IRK | 100..434 | CDD:279361 | 165/334 (49%) |
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 1 | 1.000 | 196 | 1.000 | Domainoid score | I3114 |
eggNOG | 1 | 0.900 | - | - | E1_KOG3827 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 1 | 1.000 | - | - | H7793 | |
Inparanoid | 1 | 1.050 | 363 | 1.000 | Inparanoid score | I2176 |
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 1 | 1.010 | - | - | QHG59160 | |
OrthoDB | 1 | 1.010 | - | - | D289862at33208 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 1 | 1.000 | - | - | mtm8489 | |
orthoMCL | 1 | 0.900 | - | - | OOG6_101017 | |
Panther | 1 | 1.100 | - | - | O | PTHR11767 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 1 | 1.000 | - | - | X128 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
11 | 10.880 |