Protein Alignment side-V and Skint1

DIOPT Version :10

• Sequence 1: NP_611765.2
• Gene: side-V / 37679
• FlyBaseID: FBgn0085400
• Length: 1174
• Species: Drosophila melanogaster
• Sequence 2: NP_001129388.1
• Gene: Skint1 / 689801
• RGDID: 1587579
• Length: 377
• Species: Rattus norvegicus
• Alignment Length: 508
• Identity: 91/508 - (17%)
• Similarity: 151/508 - (29%)
• Gaps: 208/508 - (40%)

  Fly    14 VAFVLVLATALSLVQGEQHPATADEGPLSEILTAVGSEVALPCDLVPGTGIVDKVQ--LVIWYRQ 76
            |.|:|.:.||.|    |....|..:.|   :|.::|..:.|.|.|.|    ..:.|  .:.|:|.
  Rat    14 VMFLLQMNTANS----ELFTVTGSDVP---VLASLGGNLELSCQLSP----PQQAQHMEIRWFRN 67

  Fly    77 GNVKPIYTF----DARGRPLNLGIPWADESVFNKKAHFHHD---TDPPALRIKNIQTSDAGLYKC 134
            ...:|::.:    |..|..:         |.:.::.....|   .....|||.|:...|.|.|.|
  Rat    68 LYREPVHLYRDGKDMFGEII---------SKYVERTELLKDGIGEGKVTLRIYNVTVDDDGFYHC 123

  Fly   135 ---RVDF---HKSPTRNWRINVTVLV---PPTALTILDHHGAEIRDQTAGPYLEGDSIDLTCLSS 190
               ..||   |.:..:...||:.|.:   ||               .|.|..:|       |.|.
  Rat   124 VFKEGDFYEEHITEVKVTAINLRVQIHVHPP---------------NTKGVIVE-------CHSG 166

  Fly   191 GGVPPPRVSWWREHALIDDSFQVLPDGSVRNVLRLKNIQRKDLLTMYTCQASNGHVVPALTKK-- 253
            |..|.|.:.|                                       :.|.|.|:||.:|.
  Rat   167 GWFPRPLMEW---------------------------------------RDSRGEVIPAASKSHS 192

  Fly   254 -------------VILDMNLPPLSLLLQGLNHAVIAGTRSHVTCTAIGARPPPEIIWSKAGQIVR 305
                         :|.|.:...::..||.    .:.|.....:.....|.....|||    :::.
  Rat   193 QGGDRLFNMKISLLISDSSFQKITCCLQN----PLTGQEGRTSVILSDAFFSWNIIW----KMIL 249

  Fly   306 GATSSTSSDGNTTISELMLIPV--------PEDNERQVVCSISLNAGITSQQLHEGHTTVMTTLG 362
            |           .|..:|::.:        ||.|..:..|......||
  Rat   250 G-----------IILFVMVLSILVSSFLLHPEHNRCRCTCDAPWVTGI----------------- 286

  Fly   363 NGHTGLYLKDSRVLNVTHAPIVNLNLGAPLDPDNLLKGTDVYLECD---------------VKAN 412
                 |.:..|.|:.::....::|....|:        :|.:.|.|               |.|.
  Rat   287 -----LIMISSVVIVISIMGYLHLKQRVPV--------SDAHFELDILWVEDLSVILCSLMVSAT 338

  Fly   413 PAITRV-----EWYHSDKQLHSSRGIIISNQTLVLQGISKSSHGQYFCRASNL 460
            ..|:..     :|.|.                ::|:|.|.::.|.. |:..:|
  Rat   339 MLISYTYFKLRDWCHK----------------IILRGTSSATDGNR-CKEPHL 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
side-V	NP_611765.2	V-set	42..153	CDD:462230	27/125 (22%)
		Ig_3	178..243	CDD:464046	7/64 (11%)
		Ig	274..359	CDD:472250	14/92 (15%)
		Ig strand B	280..284	CDD:409353	0/3 (0%)
		Ig strand C	294..298	CDD:409353	2/3 (67%)
		Ig strand E	320..324	CDD:409353	0/3 (0%)
		Ig strand F	334..345	CDD:409353	1/10 (10%)
		Ig strand G	355..358	CDD:409353	0/2 (0%)
		Ig	400..466	CDD:472250	14/81 (17%)
		Ig strand B	403..407	CDD:409353	0/3 (0%)
		Ig strand C	416..421	CDD:409353	0/9 (0%)
		Ig strand E	438..442	CDD:409353	0/3 (0%)
		Ig strand F	452..457	CDD:409353	1/4 (25%)
		Ig strand G	465..468	CDD:409353
		FN3	719..798	CDD:214495
Skint1	NP_001129388.1	IGv domain	27..141		27/129 (21%)
		IgV_MOG_like	28..141	CDD:409378	27/128 (21%)
		FR1	28..51	CDD:409378	6/25 (24%)
		Ig strand A	29..33	CDD:409378	1/3 (33%)
		Ig strand A'	36..40	CDD:409378	2/6 (33%)
		Ig strand B	43..51	CDD:409378	2/7 (29%)
		CDR1	52..60	CDD:409378	2/11 (18%)
		Ig strand C	60..65	CDD:409378	0/4 (0%)
		FR2	61..65	CDD:409378	0/3 (0%)
		CDR2	66..84	CDD:409378	3/17 (18%)
		Ig strand C'	70..78	CDD:409378	1/7 (14%)
		Ig strand C'	79..82	CDD:409378	0/2 (0%)
		FR3	86..126	CDD:409378	10/48 (21%)
		Ig strand D	93..98	CDD:409378	0/4 (0%)
		Ig strand E	104..112	CDD:409378	3/7 (43%)
		Ig strand F	119..127	CDD:409378	3/7 (43%)
		CDR3	127..129	CDD:409378	0/1 (0%)
		Ig strand G	129..141	CDD:409378	3/11 (27%)
		FR4	130..141	CDD:409378	2/10 (20%)
		IGc domain	142..228		25/150 (17%)
		transmembrane domain 1	247..269		3/32 (9%)
		transmembrane domain 2	282..304		5/43 (12%)
		transmembrane domain 3	326..348		3/21 (14%)