Protein Alignment side-V and side

DIOPT Version :10

• Sequence 1: NP_611765.2
• Gene: side-V / 37679
• FlyBaseID: FBgn0085400
• Length: 1174
• Species: Drosophila melanogaster
• Sequence 2: XP_061499735.1
• Gene: side / 1281499
• VectorBaseID: AGAMI1_000974
• Length: 949
• Species: Anopheles gambiae
• Alignment Length: 1042
• Identity: 247/1042 - (23%)
• Similarity: 398/1042 - (38%)
• Gaps: 317/1042 - (30%)

  Fly    34 ATADEGPLSEILTAVGSEVALPCDLVPGTGIVDKVQLVIWYRQGNVKPIYTFDAR-GRPLNLGIP 97
            ||.|..|...:..|:..:..||||:...:. .|.|:||:|::.....|:|:.|:| |.|::....
Mosquito   150 ATVDTIPARIVWAAIDHDAELPCDITAPSS-QDGVKLVLWFKDSTGIPLYSLDSRSGVPISAAQH 213

  Fly    98 WADESVFNKKAHFHHDTDP--PALRIKNIQTSDAGLYKCRVDFHKSPTRNWRINVTVLVPPTALT 160
            ....:...::..|.....|  ..|:|:||:|||.|:|:||||:..|||||:|:|:|:.|||....
Mosquito   214 STIANDLGQRLFFSVGATPKEARLQIRNIKTSDGGVYRCRVDYFNSPTRNYRVNLTLAVPPEEPR 278

  Fly   161 ILDHHGAEIRDQTAGPYLEGDSIDLTCLSSGGVPPPRVSWWREHALIDDSFQ---VLPDGSVRNV 222
            |.|..|.|| ...|||:.||..:.|:|..|||.|||||:|||:...|..:..   |....::.|.
Mosquito   279 IFDAQGKEI-STVAGPFREGHELFLSCQVSGGRPPPRVTWWRDGVEISSTSHPSAVEGTSAMVNQ 342

  Fly   223 LRLKNIQRKDLLTMYTCQASNGHVVPALTKKVILDMNLPPLSLLLQGLNHAVIAGTRSHVTCTAI 287
            |.:..:.|....:...|:|:....|||::|:|.:.::|.||.:.:...|..:.||....:.|.|.
Mosquito   343 LFISTVTRDFFGSKLQCRAAGSKQVPAVSKEVAIQVHLKPLRVKIISPNELLTAGRPVPIRCEAW 407

  Fly   288 GARPPPEIIWSKAGQIVRGA---TSSTSSDGNTTISELMLIPVPEDNERQVVCSISLNAGITSQQ 349
            |:.|..:|:|...|:.:|.|   ..:.|:|.|.|.|.|.|....|::..::.|..|
Mosquito   408 GSFPAAKIVWLLDGEPLRSADITVHTDSNDANLTSSILTLRVTAENDGAELTCRAS--------- 463

  Fly   350 LHEGHTTVMTTLGNGHTGLYLKDSRVLNVTHAPIVNLNLGAPLDPDNLL---KGTDVYLECDVKA 411
                        ....:|..::|.|:::|.:.|:|:::|... ||..::   :|.:|.|:|...|
Mosquito   464 ------------NPWFSGGSIEDKRIISVAYEPVVSVHLSNE-DPSRVITRAEGENVTLKCRADA 515

  Fly   412 NPAITRVEWYHSDKQLHSSRGIIISNQTLVLQGISKSSHGQYFCRASNLQGSVSSNEVYLDVKYP 476
            .|.:|...||.::.::....|     :||.|..:.:.|.|.|.|.|||.:|...|:.:.|.:::.
Mosquito   516 RPPVTSFSWYKNNMRMSGENG-----ETLYLTQLERESAGSYACAASNTEGETRSSSLTLKIQFA 575

  Fly   477 PVCK--SESTIIRAALKQTINITCEVDANPVDNLNYKWHFNNSLESLIELPQLGQGAPVMLASGS 539
            |.||  :|.|.:.:....::::.|||:|:|.|.:.:.|.:||:...          :||:
Mosquito   576 PRCKPGTEQTSVGSLNMHSLHVKCEVEADPPDGVRFSWTYNNTRNV----------SPVL----- 625

  Fly   540 DQSGYYQRSKRKHSHGMQQRLLHGRHGRMAAVRFEDEDEDGYGEFEEYGDEVGQPFTQMVYSNMV 604
                    :.|..|||:                                      .:.|.|
Mosquito   626 --------NSRISSHGL--------------------------------------VSTMTY---- 640

  Fly   605 HKNHVESSKQQQRKQLSPQQQQQQQQMASGGSSGDSHTPSGGVILERKRLVALHKQHHRGGVATP 669
                            .||...:                          ||.|
Mosquito   641 ----------------LPQSDSE--------------------------LVTL------------ 651

  Fly   670 PTTTAAPPLNNVYSYHVESYESFGAISCVASSPMG-HSAPCWYHIQPADLPEPVKNCTAYNATAN 733
                                      :|.|.:.:| .:.||..||.||.:|:..:||..:|.|.
Mosquito   652 --------------------------ACWAINNVGRQTVPCLIHILPAKIPDTPRNCELHNDTV- 689

  Fly   734 SLQIQCIPGYDGGIPQHFHAQI--------YD---------ELNRQI-----------LYNASYK 770
             |::.|..|.|||:.|.|..::        |:         |.:.:|           |:....:
Mosquito   690 -LEVVCSAGSDGGLMQSFLLEVVGGVAPPAYNLDYTRGPPTEFDNEISTMNDQATLAPLFRIQEQ 753

  Fly   771 YSEFTVKRLPSDSVFVIRITAVNAQGASK---VAYRLR-GRTLSAPLLRTASSTAVLVQLTP--- 828
            ..:|.:..|.....:.:.:.||||:|.|.   |..::| |..|..|.:   ..|.:....||
Mosquito   754 IPQFKLHSLEPGRDYQLLVYAVNAKGKSDPPFVIDKVRVGSALVPPYV---DETIISEDPTPAET 815

  Fly   829 ----------------LLGALVGVIATLILVAICVVIVIKFRSKRGGRRHGSGADATTTEADKGS 877
                            .:.|.||||...|:||..|.|.   |.||
Mosquito   816 SHQDKQKQQSQMVMFAAVAAAVGVIIASIIVAGFVAIC---RLKR-------------------- 857

  Fly   878 AEPLSRNMGSHSSLEDKNPDVVPQEANSE--------DEFHQEEKAFDRLNMESQRILYTPPTRI 934
                           .|.|:  |||....        ...:.|:..||.   |.||.|....:|.
Mosquito   858 ---------------QKPPE--PQEVRKRMRPARTDVPSMYAEDDVFDD---EYQRQLDVRCSRA 902

  Fly   935 NTASPPPPSLSPTFGKQYGELSLTTNPAFSLYNTPQRAPAVQRPVYTAPPPLLSTRTPPNIYTRI 999
            ::.......:|..| .||.:.||.                    ||.|.|.|:..|.....:|.:
Mosquito   903 SSTIRSSRYVSEGF-VQYSQPSLN--------------------VYIADPDLILPRGGDIEFTTL 946

  Fly  1000 PG 1001
            .|
Mosquito   947 SG 948

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
side-V	NP_611765.2	V-set	42..153	CDD:462230	39/113 (35%)
		Ig_3	178..243	CDD:464046	22/67 (33%)
		Ig	274..359	CDD:472250	21/87 (24%)
		Ig strand B	280..284	CDD:409353	0/3 (0%)
		Ig strand C	294..298	CDD:409353	1/3 (33%)
		Ig strand E	320..324	CDD:409353	2/3 (67%)
		Ig strand F	334..345	CDD:409353	2/10 (20%)
		Ig strand G	355..358	CDD:409353	0/2 (0%)
		Ig	400..466	CDD:472250	21/65 (32%)
		Ig strand B	403..407	CDD:409353	2/3 (67%)
		Ig strand C	416..421	CDD:409353	1/4 (25%)
		Ig strand E	438..442	CDD:409353	2/3 (67%)
		Ig strand F	452..457	CDD:409353	2/4 (50%)
		Ig strand G	465..468	CDD:409353	1/2 (50%)
		FN3	719..798	CDD:214495	24/106 (23%)
side	XP_061499735.1	None