DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Klp59D and AT3G16060

DIOPT Version :9

Sequence 1:	NP_611762.1	Gene:	Klp59D / 37674	FlyBaseID:	FBgn0034827	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_566534.1	Gene:	AT3G16060 / 820851	AraportID:	AT3G16060	Length:	684	Species:	Arabidopsis thaliana

Alignment Length:	762	Identity:	261/762 - (34%)
Similarity:	358/762 - (46%)	Gaps:	155/762 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 HQVVCTAKNLERDSITGEWTEGTVVKGKEVPLSTLIGINHHIFAENQPPISKPPSSLLPKPRGSS 84
            ||...:...|:..|..|.|.:.|             |:.|...:.|....           ....
plant    14 HQRQLSDNPLDMSSSNGRWLQST-------------GLQHFQSSANDYGY-----------YAGG 54

  Fly    85 PTGGPKTHTGNPYAERMRVQDGRSKIATRKTDPAAVGAGNHELGRAHTPRVPAGRPDRDASPTQG 149
            ..||.:...|...|:|                      ||...|...||:.       .|.||..
plant    55 QGGGGQAARGYQNAQR----------------------GNEFFGEPTTPQY-------GARPTNQ 90

  Fly   150 RKSQGGNNSNQRFSSVVREVNR----------MKEQREKRRARQAEQLQEKDALRRNNPGNPNWE 204
            ||    ||....||..:.:::.          :..|.:........|.|..|.....|. .||
plant    91 RK----NNDESEFSPGLLDLHSFDTELLPEIPVSNQLDGPSLFNPSQGQSFDDFEAYNK-QPN-- 148

  Fly   205 VSVMLRQYRSTLIFSPLRCLDPNGGTVQQITVCVRKRPMSRKEENSKNLDIITVPSADSLIVHEL 269
                    ||.::...|.........|.:|.|.|||||:::| |::||.:.|....|:.|.|||.
plant   149 --------RSRVLAENLAAEKERMNAVAKIKVVVRKRPLNKK-ESTKNEEDIVDTHANCLTVHET 204

  Fly   270 RLKVDLTKFLEHHKFRFDYTFDEECSNALVYDHTARPLIRTMFEGGNATCFAYGQTGSGKTHTMG 334
            :||||||.::|.|:|.||...|||.||..||..|..|::..:|:...||||||||||||||:||
plant   205 KLKVDLTAYVEKHEFVFDAVLDEEVSNDEVYRETVEPVVPLIFQRIKATCFAYGQTGSGKTYTM- 268

  Fly   335 GEFFGKVQDCGTGIYAMAARDVFEEVSRPEYRQMGAKITCSFFEIYGTKVFDLLLPNKPMLRVLE 399
                       ..:...|:||:. .:....||..|.::..|||||||.|::|||...| .|.:.|
plant   269 -----------KPLPLKASRDIL-RLMHHTYRNQGFQLFVSFFEIYGGKLYDLLSERK-KLCMRE 320

  Fly   400 DARQQVVVVGLTEMPVTKVEDVLRLIEHGSKERTSGQTSANAKSSRSHAVFQIAL----HFPDSW 460
            |.:|||.:|||.|..|:..:.::.|||.||..|::|.|.||.:||||||:.|:|:    ....|.
plant   321 DGKQQVCIVGLQEYRVSDTDAIMELIERGSATRSTGTTGANEESSRSHAILQLAIKKSVEGNQSK 385

  Fly   461 GPH--GKCSFVDLAGNERGADTQSADRQTRIEGAEINKSLLALKECIRALSRQSSHLPFRGSKLT 523
            .|.  ||.||:||||:||||||...|:|||:|||||||||||||||||||.....|:||||||||
plant   386 PPRLVGKLSFIDLAGSERGADTTDNDKQTRLEGAEINKSLLALKECIRALDNDQGHIPFRGSKLT 450

  Fly   524 QVLRDSFVGGKKNKTCMIAMISPSMSCVENTLNTLRYADRVKEL----IAKEDEHLQSVE-GDGE 583
            :||||||:|  .::|.||:.||||....|:||||||||||||.|    .:|:|....::. .:..
plant   451 EVLRDSFMG--NSRTVMISCISPSSGSCEHTLNTLRYADRVKSLSKGNASKKDVSSSTMNLREST 513

  Fly   584 KSP-------------DLNEESEPEMMADEEGDE---EPEDEDNQHLTISSEEASSYNNMSYDMS 632
            |.|             |:||      |..||.||   ...::|.|....:.:...|||.|:.:..
plant   514 KIPLSSALPTPSNFDDDVNE------MWTEENDEFDASDYEQDKQMWKKNGKLEPSYNGMAQERI 572

  Fly   633 FNHTLNILGPSRNVDIQEVAEQ------HALLVENLE-TYAHNFRQLKTDKEIEQYTQNSESALM 690
            ...|:.:  .||::...::.:.      :|||.|..: ..||.       |::|. |.|.....|
plant   573 PKPTIQM--KSRDMPRPDMKKSNSDDNLNALLQEEEDLVNAHR-------KQVED-TMNIVKEEM 627

  Fly   691 KLLAMVNRTRDVTHNY----NT---QK---LLKEENQNAYKKGELDE 727
            .||...::..:....|    ||   ||   :|:.:|:.|:.:..|.|
plant   628 NLLVEADQPGNQLDGYISRLNTILSQKAAGILQLQNRLAHFQKRLRE 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	174/337 (52%)
Klp59D	NP_611762.1	Kinesin	239..566	CDD:278646	172/332 (52%)
AT3G16060	NP_566534.1	KISc_KIF2_like	169..490	CDD:276818	174/337 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	319	1.000	Domainoid score	I283
eggNOG	1	0.900	-	-		E2759_KOG0246
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	329	1.000	Inparanoid score	I681
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D418348at2759
OrthoFinder	1	1.000	-	-		FOG0001531
OrthoInspector	1	1.000	-	-		mtm1030
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X866
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.830