Protein Alignment Klp59D and cmet

DIOPT Version :9

• Sequence 1: NP_611762.1
• Gene: Klp59D / 37674
• FlyBaseID: FBgn0034827
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_524993.3
• Gene: cmet / 53561
• FlyBaseID: FBgn0040232
• Length: 2189
• Species: Drosophila melanogaster
• Alignment Length: 620
• Identity: 168/620 - (27%)
• Similarity: 264/620 - (42%)
• Gaps: 183/620 - (29%)

  Fly   227 NGGTVQQITVCVRKRPMSRKEENSKNLDIITVPSADSLIVHELRLKVDLTKFLEHH--KFRFDYT 289
            |..::|   ||::.||..              |...||...:.|..:.|.   :.|  .:.|||.
  Fly     5 NASSIQ---VCIKVRPCE--------------PGLTSLWQVKERRSIHLA---DSHAEPYVFDYV 49

  Fly   290 FDEECSNALVYDHTARPLIRTMFEGGNATCFAYGQTGSGKTHTMGGEFFGKVQDCGTGIYAMAAR 354
            |||..||..|:|..|:.::....:|.|.|.||||||.||||:||.|:      :...|:..:||:
  Fly    50 FDEGASNQEVFDRMAKHIVHACMQGFNGTIFAYGQTSSGKTYTMMGD------EQNPGVMVLAAK 108

  Fly   355 DVFEEVSRPEYRQMGAKITCSFFEIYGTKVFDLLLPNKPMLRVLEDARQQVVVVGLTEMPVTKVE 419
            ::|:::|....|....::  .:.|||..|::|||......|::.|.. ..:|.|...|..:|...
  Fly   109 EIFQQISSETERDFLLRV--GYIEIYNEKIYDLLNKKNQDLKIHESG-NGIVNVNCEECIITSEV 170

  Fly   420 DVLRLIEHGSKERTSGQTSANAKSSRSHAVFQIAL------HFPDSWGPHGKCSFVDLAGNERGA 478
            |:|||:..|:||||.|:|:.|.:||||||:|:|.:      |..|........:.|||||:|| |
  Fly   171 DLLRLLCLGNKERTVGETNMNERSSRSHAIFKIIIESRKSDHSDDDAVIQSVLNLVDLAGSER-A 234

  Fly   479 DTQSADRQTRI-EGAEINKSLLALKECIRALSRQSSH--LPFRGSKLTQVLRDSFVGGKKNKTCM 540
            | |:..|..|: ||..||||||.|...|::||..:.:  ..:|.||||::|:.| :||.. .|.:
  Fly   235 D-QTGARGARLKEGGHINKSLLFLSNVIKSLSENADNRFTNYRDSKLTRILQAS-LGGNA-FTSI 296

  Fly   541 IAMISPSMSCVENTLNTLRYADRVKELIAKEDEHLQSVEGDGEKSPDLNE-----------ESEP 594
            |..|.||:  :|.:.:||.:|.|.|::..|               |.:||           |.|.
  Fly   297 ICTIKPSI--MEESQSTLSFATRAKKIRIK---------------PQVNEMVSDATMMKRLEREI 344

  Fly   595 EMMADEEGDEEPEDEDNQ-----------------------------------------HLTISS 618
            :::.|:..:||.::|:.|                                         ||.: :
  Fly   345 KVLKDKLAEEERKNENQQKVEHLERQIKHDMHKIICGHSLSDKGQQKRRRTWCPTASGSHLEL-A 408

  Fly   619 EEASSYNNMSYDMSFNH---------------------TLNILGPSRNVDIQEVAEQHALLVENL 662
            |..::.:.:......:|                     |:||||   ::||.  .|.:::..|.|
  Fly   409 ETGTTEDRIDQFPKVSHLPKPVFFHTSNAGKRWDNIPKTINILG---SLDIG--TESNSISEEFL 468

  Fly   663 ETYAHNF--------------RQ-----------LKTDK------EIEQYTQ---------NSES 687
            .....:|              ||           |.|||      :::.:|.         ....
  Fly   469 PAECIDFGSPRPDVLKPMLTIRQLPDLPLTPKGPLTTDKIKKEIQDLQMFTSLEKHFEVECEEVQ 533

  Fly   688 ALMKLLAMVNRTRDVTHNYNTQKLLKEENQNAYKK 722
            .|.:.||.|...||   |...:.|.::|..:|.:|
  Fly   534 GLKEKLAEVTAQRD---NLEQESLAEKERYDALEK 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	121/342 (35%)
		Kinesin	239..566	CDD:278646	119/337 (35%)
cmet	NP_524993.3	KISc	8..328	CDD:214526	125/369 (34%)
		Motor_domain	8..321	CDD:277568	123/347 (35%)
		Smc	<680..1449	CDD:224117
		TMPIT	779..>867	CDD:285135
		Smc	1042..1910	CDD:224117

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437833
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930