Protein Alignment Klp59D and sub

DIOPT Version :9

• Sequence 1: NP_611762.1
• Gene: Klp59D / 37674
• FlyBaseID: FBgn0034827
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_001286548.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Alignment Length: 656
• Identity: 174/656 - (26%)
• Similarity: 256/656 - (39%)
• Gaps: 176/656 - (26%)

  Fly   169 VNRMKEQREKRRARQAEQLQEKDALRRNNPGNPNWEVSVMLRQYRSTLIFSPLRCL-----DPNG 228
            ::|....|..::.|..:.:||.:....:...:...|.     :|:|:.......|.     ..|.
  Fly    25 IDRRFRPRPNKKMRLFDNIQESEEESFSEYSDTESEY-----KYQSSEATEGASCATSAADSSNV 84

  Fly   229 GTVQQITVCVRKRPMSRKEENSKNLDIITVPSADSLIVHELRLKVDLT----KFLEHHKFRFDYT 289
            .|..|  |.:|.||:   ::.||  ..|....|:.||.   ..|||.|    ..:|.| |.|...
  Fly    85 ETGPQ--VFLRLRPV---KDASK--AYIVSEEANVLIT---SCKVDSTSNNVNRMEKH-FGFTSI 138

  Fly   290 FDEECSNALVYDHTARPLIRTMFEGGNATCFAYGQTGSGKTHTMGGEFFGKVQDCGTGIYAMAAR 354
            ||.......:||....|.|   .|....|...||.:|||||:|:.|:      |...||...|..
  Fly   139 FDSTVGQRDIYDTCVGPKI---MEEECVTIMTYGTSGSGKTYTLLGD------DVRAGIIPRALE 194

  Fly   355 DVF----EEVSR-PEYRQMGAKIT--------------------C-------------------- 374
            ::|    :.|.| |:.:.:...|.                    |
  Fly   195 NIFTIYQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMF 259

  Fly   375 --------------SFFEIYGTKVFDLL-----------LPNKPMLRVLEDARQQVVVVGLTEMP 414
                          ||.|||...|:|||           :|.| .|:::.: :..|.:.|||.:.
  Fly   260 ETKASTDVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRK-NLKIVGN-KGHVFIKGLTSVF 322

  Fly   415 VTKVEDVLRLIEHGSKERTSGQTSANAKSSRSHAVFQIALHFPDSWG--PHGKCSFVDLAGNERG 477
            ||..|:.|||:..|.:..|...||.||.|||||.||.:.:...:..|  ......|.||||:||.
  Fly   323 VTSSEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSGITTQSSYKFCDLAGSERV 387

  Fly   478 ADTQSADRQTRIEGAEINKSLLALKECIRALS-----RQSSHLPFRGSKLTQVLRDSFVGGKKNK 537
            .:|.::..:.: |...||.||:.|..|:.|.|     :.:..:|:|.||||.:|:.:.:|  |.|
  Fly   388 NNTGTSGLRLK-EAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAALLG--KEK 449

  Fly   538 TCMIAMISPSMSCVENTLNTLRYADRVKELIAKE---DEHLQSVEGDGEKSPDLNEESEPEMMAD 599
            ..||..::|.....|..||.|.:|...|.:|.||   .:|..|..|..|.|         :|...
  Fly   450 LAMIVTVTPLDKYYEENLNVLNFASIAKNIIFKEPVIKQHRVSYCGFMEFS---------KMSTC 505

  Fly   600 EEGD--EEPEDEDNQHLTISSEEASSYNNMSYDMSFNHTLNILGPSRNVDIQEVAEQHALLVENL 662
            |.||  :|.||| |..|.:..|:          :.::|.|                |..||.|.|
  Fly   506 EGGDYTKELEDE-NVRLQLEIEQ----------LKYDHVL----------------QMQLLEEKL 543

  Fly   663 ETYAHNFRQL-KTDKEI-----EQYTQNSESALMKLLAMVNRTRDVTHNYNTQKLLKEENQNAYK 721
            .      |:| .|.:||     :||....|..|  |:|.    |:.....::|:...|| |....
  Fly   544 R------RELTATYQEIIQNNKKQYEDECEKKL--LIAQ----RESEFMLSSQRRRYEE-QIEDL 595

  Fly   722 KGELDE 727
            |.|::|
  Fly   596 KDEIEE 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	117/412 (28%)
		Kinesin	239..566	CDD:278646	115/407 (28%)
sub	NP_001286548.1	KISc	89..477	CDD:276812	117/412 (28%)
		Kinesin	93..479	CDD:278646	116/408 (28%)
		GBP_C	<512..603	CDD:303769	33/130 (25%)
		coiled coil	576..586	CDD:293879	1/9 (11%)
		coiled coil	592..603	CDD:293879	3/10 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437785
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940